Details for: Fgl2

Gene ID: 14190

Symbol: Fgl2

Ensembl ID: ENSMUSG00000039899

Description: fibrinogen-like protein 2

Associated with

  • Immune system
    (R-MMU-168256)
  • Innate immune system
    (R-MMU-168249)
  • Neutrophil degranulation
    (R-MMU-6798695)
  • Collagen-containing extracellular matrix
    (GO:0062023)
  • Extracellular region
    (GO:0005576)
  • Extracellular space
    (GO:0005615)
  • Immunoglobulin production involved in immunoglobulin-mediated immune response
    (GO:0002381)
  • Killing of cells of another organism
    (GO:0031640)
  • Negative regulation of defense response to virus
    (GO:0050687)
  • Negative regulation of dendritic cell antigen processing and presentation
    (GO:0002605)
  • Negative regulation of macrophage antigen processing and presentation
    (GO:0002617)
  • Negative regulation of memory t cell differentiation
    (GO:0043381)
  • T cell activation via t cell receptor contact with antigen bound to mhc molecule on antigen presenting cell
    (GO:0002291)

Other Information

Genular Protein ID: 161340181

Symbol: FGL2_MOUSE

Name: Fibroleukin

UniProtKB Accession Codes:

P12804

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CCDS 1 CDD 1 CTD 1 ChiTaRS 1 DNASU 1 EMBL 4 EPD 1 Ensembl 1 ExpressionAtlas 1 GO 8 Gene3D 1 GeneTree 1 Genevisible 1 GlyCosmos 1 GlyGen 1 HOGENOM 1 InParanoid 1 InterPro 4 KEGG 1 MGI 1 NCBI Taxonomy 1 NCBIfam 1 OMA 1 OrthoDB 1 PANTHER 2 PIR 2 PRO 1 PROSITE 2 PROSITE-ProRule 1 PaxDb 1 PeptideAtlas 1 Pfam 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 1 RNAct 1 Reactome 1 RefSeq 1 SAM 1 SMART 1 SMR 1 STRING 1 SUPFAM 1 SwissPalm 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1

Citations:

PubMed ID: 3550794

Title: Structure of a cytotoxic T-lymphocyte-specific gene shows a strong homology to fibrinogen beta and gamma chains.

PubMed ID: 3550794

DOI: 10.1073/pnas.84.6.1609

PubMed ID: 7609073

Title: Association of mouse fibrinogen-like protein with murine hepatitis virus-induced prothrombinase activity.

PubMed ID: 7609073

DOI: 10.1128/jvi.69.8.5033-5038.1995

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 10187767

Title: The nucleocapsid protein of murine hepatitis virus type 3 induces transcription of the novel fgl2 prothrombinase gene.

PubMed ID: 10187767

DOI: 10.1074/jbc.274.15.9930

Sequence Information:

  • Length: 432
  • Mass: 48951
  • Checksum: 2B297F69CCB4A782
  • Sequence:
    • MRLPGWLWLS SAVLAACRAV EEHNLTEGLE DASAQAACPA RLEGSGRCEG SQCPFQLTLP 
TLTIQLPRQL GSMEEVLKEV RTLKEAVDSL KKSCQDCKLQ ADDHRDPGGN GGNGAETAED 
SRVQELESQV NKLSSELKNA KDQIQGLQGR LETLHLVNMN NIENYVDNKV ANLTVVVNSL 
DGKCSKCPSQ EHMQSQPVQH LIYKDCSDHY VLGRRSSGAY RVTPDHRNSS FEVYCDMETM 
GGGWTVLQAR LDGSTNFTRE WKDYKAGFGN LEREFWLGND KIHLLTKSKE MILRIDLEDF 
NGLTLYALYD QFYVANEFLK YRLHIGNYNG TAGDALRFSR HYNHDLRFFT TPDRDNDRYP 
SGNCGLYYSS GWWFDSCLSA NLNGKYYHQK YKGVRNGIFW GTWPGINQAQ PGGYKSSFKQ 
AKMMIRPKNF KP

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.