Details for: Fgr
Associated with
Other Information
Genular Protein ID: 2205878218
Symbol: FGR_MOUSE
Name: Tyrosine-protein kinase Fgr
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 2674853
Title: Cloning of the murine c-fgr proto-oncogene cDNA and induction of c-fgr expression by proliferation and activation factors in normal bone marrow-derived monocytic cells.
PubMed ID: 2674853
PubMed ID: 2179817
Title: Molecular cloning and sequencing of the murine c-fgr gene.
PubMed ID: 2179817
PubMed ID: 16141072
Title: The transcriptional landscape of the mammalian genome.
PubMed ID: 16141072
PubMed ID: 19468303
Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.
PubMed ID: 19468303
PubMed ID: 8125254
Title: Functional overlap in the src gene family: inactivation of hck and fgr impairs natural immunity.
PubMed ID: 8125254
DOI: 10.1101/gad.8.4.387
PubMed ID: 8666673
Title: Deficiency of Src family kinases p59/61hck and p58c-fgr results in defective adhesion-dependent neutrophil functions.
PubMed ID: 8666673
PubMed ID: 9687507
Title: A beta 1 integrin signaling pathway involving Src-family kinases, Cbl and PI-3 kinase is required for macrophage spreading and migration.
PubMed ID: 9687507
PubMed ID: 10662797
Title: Negative regulation of phagocytosis in murine macrophages by the Src kinase family member, Fgr.
PubMed ID: 10662797
PubMed ID: 11672534
Title: Inhibition of beta 2 integrin receptor and Syk kinase signaling in monocytes by the Src family kinase Fgr.
PubMed ID: 11672534
PubMed ID: 15561106
Title: The proto-oncogene Fgr regulates cell migration and this requires its plasma membrane localization.
PubMed ID: 15561106
PubMed ID: 16439675
Title: Dual function for the adaptor MIST in IFN-gamma production by NK and CD4+NKT cells regulated by the Src kinase Fgr.
PubMed ID: 16439675
PubMed ID: 16684964
Title: Identification of Y589 and Y599 in the juxtamembrane domain of Flt3 as ligand-induced autophosphorylation sites involved in binding of Src family kinases and the protein tyrosine phosphatase SHP2.
PubMed ID: 16684964
PubMed ID: 19144319
Title: The phagosomal proteome in interferon-gamma-activated macrophages.
PubMed ID: 19144319
PubMed ID: 21183079
Title: A tissue-specific atlas of mouse protein phosphorylation and expression.
PubMed ID: 21183079
PubMed ID: 19903482
Title: c-Abl and Src-family kinases cross-talk in regulation of myeloid cell migration.
PubMed ID: 19903482
PubMed ID: 21746961
Title: The Src family kinase Fgr is critical for activation of mast cells and IgE-mediated anaphylaxis in mice.
PubMed ID: 21746961
Sequence Information:
- Length: 517
- Mass: 58867
- Checksum: 87DF5B19BF3F4734
- Sequence:
MGCVFCKKLE PASKEDVGLE GDFRSQTAEE RYFPDPTQGR TSSVFPQPTS PAFLNTGNMR SISGTGVTIF VALYDYEART GDDLTFTKGE KFHILNNTEY DWWEARSLSS GHRGYVPSNY VAPVDSIQAE EWYFGKISRK DAERQLLSSG NPQGAFLIRE SETTKGAYSL SIRDWDQNRG DHIKHYKIRK LDTGGYYITT RAQFDSIQDL VRHYMEVNDG LCYLLTAPCT TTKPQTLGLA KDAWEIDRNS IALERRLGTG CFGDVWLGTW NCSTKVAVKT LKPGTMSPKA FLEEAQIMKL LRHDKLVQLY AVVSEEPIYI VTEFMCYGSL LDFLKDREGQ NLMLPHLVDM AAQVAEGMAY MERMNYIHRD LRAANILVGE YLICKIADFG LARLIEDNEY NPQQGTKFPI KWTAPEAALF GRFTVKSDVW SFGILLTELI TKGRVPYPGM NNREVLEQVE HGYHMPCPPG CPASLYEVME QAWRLDPEER PTFEYLQSFL EDYFTSTEPQ YQPGDQT
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.