Details for: CRYGC

Gene ID: 1420

Symbol: CRYGC

Ensembl ID: ENSG00000163254

Description: crystallin gamma C

Associated with

Other Information

Genular Protein ID: 2849810845

Symbol: CRGC_HUMAN

Name: Gamma-crystallin C

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 4065573

Title: Two human gamma-crystallin genes are linked and riddled with Alu-repeats.

PubMed ID: 4065573

DOI: 10.1016/0378-1119(85)90218-5

PubMed ID: 4033658

Title: Structural and evolutionary relationships among five members of the human gamma-crystallin gene family.

PubMed ID: 4033658

DOI: 10.1128/mcb.5.6.1408-1414.1985

PubMed ID: 2777080

Title: Nucleotide sequence of the rat gamma-crystallin gene region and comparison with an orthologous human region.

PubMed ID: 2777080

DOI: 10.1016/0378-1119(89)90223-0

PubMed ID: 15815621

Title: Generation and annotation of the DNA sequences of human chromosomes 2 and 4.

PubMed ID: 15815621

DOI: 10.1038/nature03466

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 8999933

Title: Sequence analysis of betaA3, betaB3, and betaA4 crystallins completes the identification of the major proteins in young human lens.

PubMed ID: 8999933

DOI: 10.1074/jbc.272.4.2268

PubMed ID: 12876325

Title: Methylation and carbamylation of human gamma-crystallins.

PubMed ID: 12876325

DOI: 10.1110/ps.0305403

PubMed ID: 22876111

Title: A nonsense mutation of CRYGC associated with autosomal dominant congenital nuclear cataracts and microcornea in a Chinese pedigree.

PubMed ID: 22876111

PubMed ID: 12507494

Title: Homology models of human gamma-crystallins: structural study of the extensive charge network in gamma-crystallins.

PubMed ID: 12507494

DOI: 10.1016/s0006-291x(02)02895-4

PubMed ID: 10521291

Title: The gamma-crystallins and human cataracts: a puzzle made clearer.

PubMed ID: 10521291

DOI: 10.1086/302619

PubMed ID: 10914683

Title: A 5-base insertion in the gammaC-crystallin gene is associated with autosomal dominant variable zonular pulverulent cataract.

PubMed ID: 10914683

DOI: 10.1007/s004390000289

PubMed ID: 12011157

Title: Novel mutations in the gamma-crystallin genes cause autosomal dominant congenital cataracts.

PubMed ID: 12011157

DOI: 10.1136/jmg.39.5.352

PubMed ID: 12601044

Title: Alteration of protein-protein interactions of congenital cataract crystallin mutants.

PubMed ID: 12601044

DOI: 10.1167/iovs.02-0950

PubMed ID: 18587492

Title: Crystallin gene mutations in Indian families with inherited pediatric cataract.

PubMed ID: 18587492

PubMed ID: 21423869

Title: Mutation screening and genotype phenotype correlation of alpha-crystallin, gamma-crystallin and GJA8 gene in congenital cataract.

PubMed ID: 21423869

PubMed ID: 22052681

Title: A novel mutation impairing the tertiary structure and stability of gammaC-crystallin (CRYGC) leads to cataract formation in humans and zebrafish lens.

PubMed ID: 22052681

DOI: 10.1002/humu.21648

PubMed ID: 29386872

Title: Mutations in crystallin genes result in congenital cataract associated with other ocular abnormalities.

PubMed ID: 29386872

PubMed ID: 29914532

Title: Clinical and genetic characteristics of Chinese patients with familial or sporadic pediatric cataract.

PubMed ID: 29914532

DOI: 10.1186/s13023-018-0828-0

PubMed ID: 33243271

Title: The genetic landscape of crystallins in congenital cataract.

PubMed ID: 33243271

DOI: 10.1186/s13023-020-01613-3

Sequence Information:

  • Length: 174
  • Mass: 20879
  • Checksum: B01DC167171A7668
  • Sequence:
  • MGKITFYEDR AFQGRSYETT TDCPNLQPYF SRCNSIRVES GCWMLYERPN YQGQQYLLRR 
    GEYPDYQQWM GLSDSIRSCC LIPQTVSHRL RLYEREDHKG LMMELSEDCP SIQDRFHLSE 
    IRSLHVLEGC WVLYELPNYR GRQYLLRPQE YRRCQDWGAM DAKAGSLRRV VDLY

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.