Details for: CRYGD

Gene ID: 1421

Symbol: CRYGD

Ensembl ID: ENSG00000118231

Description: crystallin gamma D

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 32.9808
    Cell Significance Index: -5.1300
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: 21.5778
    Cell Significance Index: 294.4000
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 4.2824
    Cell Significance Index: -5.2800
  • Cell Name: photoreceptor cell (CL0000210)
    Fold Change: 2.3054
    Cell Significance Index: 32.3800
  • Cell Name: keratocyte (CL0002363)
    Fold Change: 1.8298
    Cell Significance Index: 29.0300
  • Cell Name: lens fiber cell (CL0011004)
    Fold Change: 1.3014
    Cell Significance Index: 41.1600
  • Cell Name: thymocyte (CL0000893)
    Fold Change: 0.9086
    Cell Significance Index: 11.4800
  • Cell Name: immature innate lymphoid cell (CL0001082)
    Fold Change: 0.8161
    Cell Significance Index: 10.1000
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: 0.5479
    Cell Significance Index: 34.5300
  • Cell Name: adipocyte (CL0000136)
    Fold Change: 0.5019
    Cell Significance Index: 6.6900
  • Cell Name: pro-T cell (CL0000827)
    Fold Change: 0.4956
    Cell Significance Index: 12.6600
  • Cell Name: glioblast (CL0000030)
    Fold Change: 0.2516
    Cell Significance Index: 1.5800
  • Cell Name: lymphoid lineage restricted progenitor cell (CL0000838)
    Fold Change: 0.1918
    Cell Significance Index: 2.4300
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 0.1840
    Cell Significance Index: 283.2400
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 0.1726
    Cell Significance Index: 318.3900
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: 0.1670
    Cell Significance Index: 9.3700
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: 0.1018
    Cell Significance Index: 138.4200
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: 0.0890
    Cell Significance Index: 25.6200
  • Cell Name: intestinal epithelial cell (CL0002563)
    Fold Change: 0.0763
    Cell Significance Index: 0.7900
  • Cell Name: early promyelocyte (CL0002154)
    Fold Change: 0.0674
    Cell Significance Index: 0.4300
  • Cell Name: radial glial cell (CL0000681)
    Fold Change: 0.0202
    Cell Significance Index: 0.1200
  • Cell Name: neuron associated cell (CL0000095)
    Fold Change: -0.0009
    Cell Significance Index: -0.0400
  • Cell Name: fibroblast of dermis (CL0002551)
    Fold Change: -0.0010
    Cell Significance Index: -0.0200
  • Cell Name: odontoblast (CL0000060)
    Fold Change: -0.0077
    Cell Significance Index: -0.9900
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0098
    Cell Significance Index: -7.2500
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0125
    Cell Significance Index: -7.0300
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0141
    Cell Significance Index: -6.4000
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: -0.0168
    Cell Significance Index: -6.0300
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: -0.0174
    Cell Significance Index: -3.4900
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: -0.0202
    Cell Significance Index: -2.7800
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.0330
    Cell Significance Index: -6.9500
  • Cell Name: fibroblast of connective tissue of nonglandular part of prostate (CL1000304)
    Fold Change: -0.0339
    Cell Significance Index: -0.3700
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.0374
    Cell Significance Index: -5.4300
  • Cell Name: forebrain radial glial cell (CL0013000)
    Fold Change: -0.0399
    Cell Significance Index: -0.2900
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: -0.0403
    Cell Significance Index: -1.1000
  • Cell Name: Mueller cell (CL0000636)
    Fold Change: -0.0465
    Cell Significance Index: -0.3600
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.0559
    Cell Significance Index: -6.4000
  • Cell Name: corneal epithelial cell (CL0000575)
    Fold Change: -0.0652
    Cell Significance Index: -0.9300
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: -0.0713
    Cell Significance Index: -3.7500
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: -0.0771
    Cell Significance Index: -2.7000
  • Cell Name: paneth cell (CL0000510)
    Fold Change: -0.0783
    Cell Significance Index: -0.8100
  • Cell Name: fibroblast of connective tissue of glandular part of prostate (CL1000305)
    Fold Change: -0.0866
    Cell Significance Index: -0.9600
  • Cell Name: CD14-low, CD16-positive monocyte (CL0002396)
    Fold Change: -0.0894
    Cell Significance Index: -2.1700
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: -0.0951
    Cell Significance Index: -2.5000
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: -0.0987
    Cell Significance Index: -6.3700
  • Cell Name: smooth muscle cell of prostate (CL1000487)
    Fold Change: -0.0999
    Cell Significance Index: -1.1600
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: -0.1011
    Cell Significance Index: -4.4700
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: -0.1173
    Cell Significance Index: -4.4400
  • Cell Name: VIP GABAergic cortical interneuron (CL4023016)
    Fold Change: -0.1225
    Cell Significance Index: -2.4600
  • Cell Name: luminal cell of prostate epithelium (CL0002340)
    Fold Change: -0.1229
    Cell Significance Index: -1.2700
  • Cell Name: neural progenitor cell (CL0011020)
    Fold Change: -0.1233
    Cell Significance Index: -1.2200
  • Cell Name: myeloid lineage restricted progenitor cell (CL0000839)
    Fold Change: -0.1261
    Cell Significance Index: -1.7700
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: -0.1275
    Cell Significance Index: -4.4300
  • Cell Name: proerythroblast (CL0000547)
    Fold Change: -0.1326
    Cell Significance Index: -1.9000
  • Cell Name: CD8-positive, alpha-beta thymocyte (CL0000811)
    Fold Change: -0.1340
    Cell Significance Index: -1.2400
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: -0.1348
    Cell Significance Index: -3.8800
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -0.1359
    Cell Significance Index: -4.4500
  • Cell Name: prostate gland microvascular endothelial cell (CL2000059)
    Fold Change: -0.1406
    Cell Significance Index: -1.0100
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -0.1425
    Cell Significance Index: -4.5400
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: -0.1452
    Cell Significance Index: -2.4300
  • Cell Name: L5/6 near-projecting glutamatergic neuron (CL4030067)
    Fold Change: -0.1482
    Cell Significance Index: -0.7800
  • Cell Name: basophil mast progenitor cell (CL0002028)
    Fold Change: -0.1517
    Cell Significance Index: -1.2800
  • Cell Name: cerebral cortex GABAergic interneuron (CL0010011)
    Fold Change: -0.1552
    Cell Significance Index: -1.5600
  • Cell Name: tendon cell (CL0000388)
    Fold Change: -0.1559
    Cell Significance Index: -2.1200
  • Cell Name: Purkinje cell (CL0000121)
    Fold Change: -0.1626
    Cell Significance Index: -3.5600
  • Cell Name: primitive red blood cell (CL0002355)
    Fold Change: -0.1678
    Cell Significance Index: -1.9000
  • Cell Name: skeletal muscle myoblast (CL0000515)
    Fold Change: -0.1720
    Cell Significance Index: -1.8700
  • Cell Name: theca cell (CL0000503)
    Fold Change: -0.1736
    Cell Significance Index: -1.0200
  • Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
    Fold Change: -0.1740
    Cell Significance Index: -4.3400
  • Cell Name: kidney epithelial cell (CL0002518)
    Fold Change: -0.1757
    Cell Significance Index: -5.1800
  • Cell Name: keratinocyte (CL0000312)
    Fold Change: -0.1778
    Cell Significance Index: -4.4400
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: -0.1849
    Cell Significance Index: -8.6200
  • Cell Name: retinal astrocyte (CL4033015)
    Fold Change: -0.1870
    Cell Significance Index: -1.8300
  • Cell Name: obsolete epithelial cell of alveolus of lung (CL0010003)
    Fold Change: -0.1885
    Cell Significance Index: -4.7000
  • Cell Name: cytotoxic T cell (CL0000910)
    Fold Change: -0.1911
    Cell Significance Index: -2.7900
  • Cell Name: stratified epithelial cell (CL0000079)
    Fold Change: -0.1912
    Cell Significance Index: -7.0200
  • Cell Name: macroglial cell (CL0000126)
    Fold Change: -0.1965
    Cell Significance Index: -2.2800
  • Cell Name: epithelial cell of lacrimal sac (CL1000436)
    Fold Change: -0.1973
    Cell Significance Index: -1.4200
  • Cell Name: connective tissue cell (CL0002320)
    Fold Change: -0.1981
    Cell Significance Index: -1.9100
  • Cell Name: embryonic fibroblast (CL2000042)
    Fold Change: -0.2049
    Cell Significance Index: -0.9800
  • Cell Name: erythroid progenitor cell (CL0000038)
    Fold Change: -0.2068
    Cell Significance Index: -2.7100
  • Cell Name: endothelial cell of artery (CL1000413)
    Fold Change: -0.2069
    Cell Significance Index: -2.1800
  • Cell Name: pulmonary alveolar type 1 cell (CL0002062)
    Fold Change: -0.2077
    Cell Significance Index: -2.2800
  • Cell Name: CD14-positive monocyte (CL0001054)
    Fold Change: -0.2089
    Cell Significance Index: -4.0900
  • Cell Name: early T lineage precursor (CL0002425)
    Fold Change: -0.2104
    Cell Significance Index: -3.0600
  • Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
    Fold Change: -0.2119
    Cell Significance Index: -3.0400
  • Cell Name: fibroblast of lung (CL0002553)
    Fold Change: -0.2171
    Cell Significance Index: -2.5800
  • Cell Name: chandelier pvalb GABAergic cortical interneuron (CL4023036)
    Fold Change: -0.2185
    Cell Significance Index: -4.5600
  • Cell Name: erythrocyte (CL0000232)
    Fold Change: -0.2186
    Cell Significance Index: -5.5700
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: -0.2209
    Cell Significance Index: -5.9200
  • Cell Name: sst GABAergic cortical interneuron (CL4023017)
    Fold Change: -0.2276
    Cell Significance Index: -4.5000
  • Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
    Fold Change: -0.2314
    Cell Significance Index: -5.0000
  • Cell Name: blood vessel smooth muscle cell (CL0019018)
    Fold Change: -0.2341
    Cell Significance Index: -2.2100
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: -0.2342
    Cell Significance Index: -4.9700
  • Cell Name: mature T cell (CL0002419)
    Fold Change: -0.2394
    Cell Significance Index: -1.7200
  • Cell Name: neuroblast (sensu Nematoda and Protostomia) (CL0000338)
    Fold Change: -0.2395
    Cell Significance Index: -2.1800
  • Cell Name: interstitial cell of ovary (CL0002094)
    Fold Change: -0.2397
    Cell Significance Index: -3.0700
  • Cell Name: megakaryocyte-erythroid progenitor cell (CL0000050)
    Fold Change: -0.2436
    Cell Significance Index: -3.3400
  • Cell Name: retinal ganglion cell (CL0000740)
    Fold Change: -0.2447
    Cell Significance Index: -2.0200
  • Cell Name: eukaryotic cell (CL0000255)
    Fold Change: -0.2464
    Cell Significance Index: -10.7200

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** 1. **Expression Pattern:** CRYGD is highly expressed in lens development, lens fiber cell differentiation, and visual perception, highlighting its critical role in maintaining the structural integrity of the eye lens. 2. **Protein Structure:** The protein encoded by CRYGD, CRGD_HUMAN, is a member of the gamma-crystallin family, which consists of four subunits (A, B, C, and D). The D subunit is unique in that it does not form a stable crystal lattice structure, but rather interacts with other subunits to maintain the overall structure of the lens. 3. **Cellular Localization:** CRYGD is predominantly expressed in anterior lens cells, lens epithelial cells, and secondary lens fibers, indicating its role in lens development and maintenance. 4. **Functional Implications:** The gamma-crystallin family, including CRYGD, is essential for maintaining the transparency and refractive index of the lens, which is critical for clear vision. **Pathways and Functions:** 1. **Cellular Response to Reactive Oxygen Species (ROS):** CRYGD has been implicated in the cellular response to ROS, which are highly reactive molecules that can damage cellular components. The gamma-crystallin family, including CRYGD, plays a crucial role in protecting the lens from oxidative stress. 2. **Protein Binding:** CRGD_HUMAN interacts with other proteins, including the gamma-A-crystallin, to form a stable crystal lattice structure that maintains the transparency and refractive index of the lens. 3. **Lens Development and Differentiation:** CRYGD is essential for lens development and differentiation, as it regulates the expression of other genes involved in these processes. 4. **Visual Perception:** The gamma-crystallin family, including CRYGD, plays a critical role in maintaining the refractive index and transparency of the lens, which is essential for clear vision. **Clinical Significance:** 1. **Eye Diseases:** Mutations in the CRYGD gene have been associated with various eye diseases, including cataracts, which are a leading cause of blindness worldwide. 2. **Neurodegenerative Diseases:** The gamma-crystallin family, including CRYGD, has been implicated in neurodegenerative diseases, such as Alzheimer's disease and Parkinson's disease, where oxidative stress and protein misfolding are key mechanisms. 3. **Cancer:** CRYGD has been identified as a potential biomarker for cancer, particularly in the thymus, where it is involved in the development of immune cells. 4. **Immunological Disorders:** The gamma-crystallin family, including CRYGD, plays a critical role in the development and function of immune cells, making it a potential target for the treatment of immunological disorders. In conclusion, CRYGD is a critical gene that plays a pivotal role in the structure and function of the eye lens, as well as its development and differentiation. Its involvement in various diseases, including eye diseases, neurodegenerative diseases, cancer, and immunological disorders, highlights its importance as a potential therapeutic target. Further research is necessary to fully understand the mechanisms by which CRYGD regulates cellular processes and to explore its potential applications in human disease treatment.

Genular Protein ID: 848408585

Symbol: CRGD_HUMAN

Name: Gamma-crystallin D

UniProtKB Accession Codes:

P07320 Q17RF7 Q53R51 Q99681

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 BMRB 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 1 CTD 1 ChEMBL 1 DIP 1 DMDM 1 DNASU 1 DisGeNET 1 EMBL 6 Ensembl 2 EvolutionaryTrace 1 ExpressionAtlas 1 GO 7 Gene3D 1 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 3 KEGG 1 MANE-Select 1 MIM 3 MINT 1 MalaCards 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 Orphanet 6 OrthoDB 1 PANTHER 2 PCDDB 1 PDB 15 PDBsum 15 PIR 1 PRINTS 1 PRO 1 PROSITE 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 1 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 1 Pumba 1 RNAct 1 RefSeq 1 SIGNOR 1 SMART 1 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 4033658

Title: Structural and evolutionary relationships among five members of the human gamma-crystallin gene family.

PubMed ID: 4033658

DOI: 10.1128/mcb.5.6.1408-1414.1985

PubMed ID: 15815621

Title: Generation and annotation of the DNA sequences of human chromosomes 2 and 4.

PubMed ID: 15815621

DOI: 10.1038/nature03466

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 8999933

Title: Sequence analysis of betaA3, betaB3, and betaA4 crystallins completes the identification of the major proteins in young human lens.

PubMed ID: 8999933

DOI: 10.1074/jbc.272.4.2268

PubMed ID: 15709761

Title: Decrease in protein solubility and cataract formation caused by the Pro23 to Thr mutation in human gamma D-crystallin.

PubMed ID: 15709761

DOI: 10.1021/bi0479611

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 12729747

Title: High-resolution X-ray crystal structures of human gammaD crystallin (1.25 A) and the R58H mutant (1.15 A) associated with aculeiform cataract.

PubMed ID: 12729747

DOI: 10.1016/s0022-2836(03)00375-9

PubMed ID: 12507494

Title: Homology models of human gamma-crystallins: structural study of the extensive charge network in gamma-crystallins.

PubMed ID: 12507494

DOI: 10.1016/s0006-291x(02)02895-4

PubMed ID: 10521291

Title: The gamma-crystallins and human cataracts: a puzzle made clearer.

PubMed ID: 10521291

DOI: 10.1086/302619

PubMed ID: 9927684

Title: Progressive juvenile-onset punctate cataracts caused by mutation of the gamma-D-crystallin gene.

PubMed ID: 9927684

DOI: 10.1073/pnas.96.3.1008

PubMed ID: 10915766

Title: Link between a novel human gamma-D-crystallin allele and a unique cataract phenotype explained by protein crystallography.

PubMed ID: 10915766

DOI: 10.1093/hmg/9.12.1779

PubMed ID: 10688888

Title: Molecular basis of a progressive juvenile-onset hereditary cataract.

PubMed ID: 10688888

DOI: 10.1073/pnas.040554397

PubMed ID: 11371638

Title: Crystal cataracts: human genetic cataract caused by protein crystallization.

PubMed ID: 11371638

DOI: 10.1073/pnas.101124798

PubMed ID: 12011157

Title: Novel mutations in the gamma-crystallin genes cause autosomal dominant congenital cataracts.

PubMed ID: 12011157

DOI: 10.1136/jmg.39.5.352

PubMed ID: 12676897

Title: Gamma-D crystallin gene (CRYGD) mutation causes autosomal dominant congenital cerulean cataracts.

PubMed ID: 12676897

DOI: 10.1136/jmg.40.4.262

PubMed ID: 16943771

Title: Two affected siblings with nuclear cataract associated with a novel missense mutation in the CRYGD gene.

PubMed ID: 16943771

PubMed ID: 17564961

Title: Conversion and compensatory evolution of the gamma-crystallin genes and identification of a cataractogenic mutation that reverses the sequence of the human CRYGD gene to an ancestral state.

PubMed ID: 17564961

DOI: 10.1086/518616

PubMed ID: 18587492

Title: Crystallin gene mutations in Indian families with inherited pediatric cataract.

PubMed ID: 18587492

PubMed ID: 19390652

Title: Mutation analysis of CRYAA, CRYGC, and CRYGD associated with autosomal dominant congenital cataract in Brazilian families.

PubMed ID: 19390652

PubMed ID: 21031598

Title: A novel CRYGD mutation (p.Trp43Arg) causing autosomal dominant congenital cataract in a Chinese family.

PubMed ID: 21031598

DOI: 10.1002/humu.21386

PubMed ID: 21866213

Title: Mutation analysis of 12 genes in Chinese families with congenital cataracts.

PubMed ID: 21866213

PubMed ID: 29914532

Title: Clinical and genetic characteristics of Chinese patients with familial or sporadic pediatric cataract.

PubMed ID: 29914532

DOI: 10.1186/s13023-018-0828-0

PubMed ID: 31523120

Title: Mutation screening of crystallin genes in Chinese families with congenital cataracts.

PubMed ID: 31523120

PubMed ID: 33243271

Title: The genetic landscape of crystallins in congenital cataract.

PubMed ID: 33243271

DOI: 10.1186/s13023-020-01613-3

Sequence Information:

  • Length: 174
  • Mass: 20738
  • Checksum: 437EC83FD79F12E4
  • Sequence:
    • MGKITLYEDR GFQGRHYECS SDHPNLQPYL SRCNSARVDS GCWMLYEQPN YSGLQYFLRR 
GDYADHQQWM GLSDSVRSCR LIPHSGSHRI RLYEREDYRG QMIEFTEDCS CLQDRFRFNE 
IHSLNVLEGS WVLYELSNYR GRQYLLMPGD YRRYQDWGAT NARVGSLRRV IDFS

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.