Genular: Defining Cellular Identity and Function

Details for: Fkbp4

Gene ID: 14228

Symbol: Fkbp4

Ensembl ID: ENSMUSG00000030357

Description: FK506 binding protein 4

Associated with

Attenuation phase
(R-MMU-3371568)
Cellular responses to stimuli
(R-MMU-8953897)
Cellular responses to stress
(R-MMU-2262752)
Cellular response to heat stress
(R-MMU-3371556)
Esr-mediated signaling
(R-MMU-8939211)
Estrogen-dependent gene expression
(R-MMU-9018519)
Hsf1-dependent transactivation
(R-MMU-3371571)
Hsp90 chaperone cycle for steroid hormone receptors (shr) in the presence of ligand
(R-MMU-3371497)
Signaling by nuclear receptors
(R-MMU-9006931)
Signal transduction
(R-MMU-162582)
Androgen receptor signaling pathway
(GO:0030521)
Atp binding
(GO:0005524)
Axonal growth cone
(GO:0044295)
Chaperone-mediated protein folding
(GO:0061077)
Copper-dependent protein binding
(GO:0032767)
Copper ion transport
(GO:0006825)
Cytoplasm
(GO:0005737)
Cytoskeleton
(GO:0005856)
Cytosol
(GO:0005829)
Embryo implantation
(GO:0007566)
Gtp binding
(GO:0005525)
Heat shock protein binding
(GO:0031072)
Isomerase activity
(GO:0016853)
Male sex differentiation
(GO:0046661)
Microtubule
(GO:0005874)
Mitochondrion
(GO:0005739)
Negative regulation of microtubule polymerization
(GO:0031115)
Neuronal cell body
(GO:0043025)
Nuclear glucocorticoid receptor binding
(GO:0035259)
Nucleoplasm
(GO:0005654)
Nucleus
(GO:0005634)
Peptidyl-prolyl cis-trans isomerase activity
(GO:0003755)
Perinuclear region of cytoplasm
(GO:0048471)
Phosphoprotein binding
(GO:0051219)
Prostate gland development
(GO:0030850)
Protein-containing complex
(GO:0032991)
Protein-containing complex localization
(GO:0031503)
Protein binding
(GO:0005515)
Protein peptidyl-prolyl isomerization
(GO:0000413)
Reproductive structure development
(GO:0048608)
Steroid hormone receptor complex assembly
(GO:0006463)
Tau protein binding
(GO:0048156)

Other Information

Proteins

Peptidyl-prolyl cis-trans isomerase FKBP4

Genular Protein ID: 3698859655

Symbol: FKBP4_MOUSE

Name: Peptidyl-prolyl cis-trans isomerase FKBP4

UniProtKB Accession Codes:

P30416 Q3TVC9

Database IDs:

Citations:

PubMed ID: 7693550

Title: Cloning and expression of a mouse cDNA encoding p59, an immunophilin that associates with the glucocorticoid receptor.

PubMed ID: 7693550

DOI: 10.1016/0378-1119(93)90206-i

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 8341706

Title: Overexpression, characterization, and purification of a recombinant mouse immunophilin FKBP-52 and identification of an associated phosphoprotein.

PubMed ID: 8341706

DOI: 10.1073/pnas.90.14.6839

PubMed ID: 9195923

Title: Protein phosphatase 5 is a major component of glucocorticoid receptor.hsp90 complexes with properties of an FK506-binding immunophilin.

PubMed ID: 9195923

DOI: 10.1074/jbc.272.26.16224

PubMed ID: 11278753

Title: Evidence that the peptidylprolyl isomerase domain of the hsp90-binding immunophilin FKBP52 is involved in both dynein interaction and glucocorticoid receptor movement to the nucleus.

PubMed ID: 11278753

DOI: 10.1074/jbc.m010809200

PubMed ID: 11751894

Title: A new first step in activation of steroid receptors: hormone-induced switching of FKBP51 and FKBP52 immunophilins.

PubMed ID: 11751894

DOI: 10.1074/jbc.c100531200

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

PubMed ID: 24129315

Title: Immunoaffinity enrichment and mass spectrometry analysis of protein methylation.

PubMed ID: 24129315

DOI: 10.1074/mcp.o113.027870

Sequence Information:

Length: 458
Mass: 51572
Checksum: CFB2ED49E9B6BA7A
Sequence:

MTAEEMKAAE NGAQSAPLPL EGVDISPKQD EGVLKVIKRE GTGTETPMIG DRVFVHYTGW 
LLDGTKFDSS LDRKDKFSFD LGKGEVIKAW DIAVATMKVG EVCHITCKPE YAYGAAGSPP 
KIPPNATLVF EVELFEFKGE DLTEEEDGGI IRRIRTRGEG YARPNDGAMV EVALEGYHKD 
RLFDQRELCF EVGEGESLDL PCGLEEAIQR MEKGEHSIVY LKPSYAFGSV GKERFQIPPH 
AELRYEVRLK SFEKAKESWE MSSAEKLEQS NIVKERGTAY FKEGKYKQAL LQYKKIVSWL 
EYESSFSGEE MQKVHALRLA SHLNLAMCHL KLQAFSAAIE SCNKALELDS NNEKGLFRRG 
EAHLAVNDFD LARADFQKVL QLYPSNKAAK TQLAVCQQRT RRQLAREKKL YANMFERLAE 
EEHKVKAEVA AGDHPTDAEM KGERNNVAEN QSRVETEA

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Fkbp4

Associated with

Other Information

Cloning and expression of a mouse cDNA encoding p59, an immunophilin that associates with the glucocorticoid receptor. PubMed ID: 7693550

The transcriptional landscape of the mammalian genome. PubMed ID: 16141072

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Overexpression, characterization, and purification of a recombinant mouse immunophilin FKBP-52 and identification of an associated phosphoprotein. PubMed ID: 8341706

Protein phosphatase 5 is a major component of glucocorticoid receptor.hsp90 complexes with properties of an FK506-binding immunophilin. PubMed ID: 9195923

Evidence that the peptidylprolyl isomerase domain of the hsp90-binding immunophilin FKBP52 is involved in both dynein interaction and glucocorticoid receptor movement to the nucleus. PubMed ID: 11278753

A new first step in activation of steroid receptors: hormone-induced switching of FKBP51 and FKBP52 immunophilins. PubMed ID: 11751894

A tissue-specific atlas of mouse protein phosphorylation and expression. PubMed ID: 21183079

Immunoaffinity enrichment and mass spectrometry analysis of protein methylation. PubMed ID: 24129315