Details for: Foxl1

Gene ID: 14241

Symbol: Foxl1

Ensembl ID: ENSMUSG00000097084

Description: forkhead box L1

Associated with

  • Anatomical structure morphogenesis
    (GO:0009653)
  • Cell differentiation
    (GO:0030154)
  • Dna-binding transcription factor activity
    (GO:0003700)
  • Dna-binding transcription factor activity, rna polymerase ii-specific
    (GO:0000981)
  • Dna binding
    (GO:0003677)
  • Heart development
    (GO:0007507)
  • Nucleus
    (GO:0005634)
  • Peyer's patch morphogenesis
    (GO:0061146)
  • Proteoglycan biosynthetic process
    (GO:0030166)
  • Regulation of dna-templated transcription
    (GO:0006355)
  • Regulation of transcription by rna polymerase ii
    (GO:0006357)
  • Regulation of wnt signaling pathway
    (GO:0030111)
  • Rna polymerase ii cis-regulatory region sequence-specific dna binding
    (GO:0000978)
  • Sequence-specific dna binding
    (GO:0043565)
  • Visceral mesoderm-endoderm interaction involved in midgut development
    (GO:0007495)

Other Information

Genular Protein ID: 2412238801

Symbol: FOXL1_MOUSE

Name: Forkhead box protein L1

UniProtKB Accession Codes:

Q64731 B2RQ86

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 CCDS 1 CDD 1 CTD 1 DNASU 1 EMBL 5 Ensembl 1 GO 15 Gene3D 1 GeneTree 1 Genevisible 1 HOGENOM 1 InParanoid 1 IntAct 1 InterPro 6 KEGG 1 MGI 1 MaxQB 1 NCBI Taxonomy 1 OMA 1 OrthoDB 1 PANTHER 2 PIR 1 PRINTS 1 PRO 1 PROSITE 3 PROSITE-ProRule 1 PaxDb 1 Pfam 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 1 RNAct 1 RefSeq 1 SAM 1 SMART 1 SMR 1 STRING 1 SUPFAM 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1

Citations:

PubMed ID: 8674414

Title: Clustered arrangement of winged helix genes fkh-6 and MFH-1: possible implications for mesoderm development.

PubMed ID: 8674414

DOI: 10.1242/dev.122.6.1751

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 7689224

Title: Six members of the mouse forkhead gene family are developmentally regulated.

PubMed ID: 7689224

DOI: 10.1073/pnas.90.16.7628

PubMed ID: 9203584

Title: The mesenchymal winged helix transcription factor Fkh6 is required for the control of gastrointestinal proliferation and differentiation.

PubMed ID: 9203584

DOI: 10.1101/gad.11.12.1583

PubMed ID: 15155178

Title: Foxl1 null mice have abnormal intestinal epithelia, postnatal growth retardation, and defective intestinal glucose uptake.

PubMed ID: 15155178

DOI: 10.1152/ajpgi.00136.2004

PubMed ID: 19049965

Title: FoxF1 and FoxL1 link hedgehog signaling and the control of epithelial proliferation in the developing stomach and intestine.

PubMed ID: 19049965

DOI: 10.1074/jbc.m808103200

Sequence Information:

  • Length: 336
  • Mass: 35793
  • Checksum: 244437F043BA7F43
  • Sequence:
    • MSHLFSPPLA ALAASPLLYV YSPERPGLPL AFAPAAALAG PGRVEPPQKP PYSYIALIAM 
AIQDAPEQRV TLNGIYQFIM DRFPFYHDNR QGWQNSIRHN LSLNECFVKV PREKGRPGKG 
SYWTLDPRCL DMFENGNYRR RKRKPKPAAG SPEAKRTRVE PPESEVGCDV GSPDLATALP 
TRAPDRSQSP AVGTARPALL PWPGPEPRDP DADLTVQGAG AVASGQLQRP AHHLGSPLCP 
APSGSPKGSK SKSFSIDSIL AVRPTPASGA EAPGIPKPVP GALGSSLLAA SSGLAPPFNA 
SLVFDAHVQG GFSQLGIPFL SYFPLQVPEA TVLRFH

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.