Genular: Defining Cellular Identity and Function

Details for: Flot1

Gene ID: 14251

Symbol: Flot1

Ensembl ID: ENSMUSG00000059714

Description: flotillin 1

Associated with

Neuronal system
(R-MMU-112316)
Programmed cell death
(R-MMU-5357801)
Protein-protein interactions at synapses
(R-MMU-6794362)
Regulated necrosis
(R-MMU-5218859)
Regulation of necroptotic cell death
(R-MMU-5675482)
Rhoa gtpase cycle
(R-MMU-8980692)
Rhob gtpase cycle
(R-MMU-9013026)
Rhoc gtpase cycle
(R-MMU-9013106)
Rho gtpase cycle
(R-MMU-9012999)
Ripk1-mediated regulated necrosis
(R-MMU-5213460)
Signaling by rho gtpases
(R-MMU-194315)
Signaling by rho gtpases, miro gtpases and rhobtb3
(R-MMU-9716542)
Signal transduction
(R-MMU-162582)
Synaptic adhesion-like molecules
(R-MMU-8849932)
Adherens junction
(GO:0005912)
Axon guidance
(GO:0007411)
Axonogenesis
(GO:0007409)
Basolateral plasma membrane
(GO:0016323)
Caveola
(GO:0005901)
Cell-cell contact zone
(GO:0044291)
Cell-cell junction
(GO:0005911)
Cellular response to exogenous dsrna
(GO:0071360)
Centriolar satellite
(GO:0034451)
Cop9 signalosome
(GO:0008180)
Cortical actin cytoskeleton
(GO:0030864)
Cytoplasmic vesicle
(GO:0031410)
Dopaminergic synapse
(GO:0098691)
Dsrna transport
(GO:0033227)
Early endosome
(GO:0005769)
Endocytosis
(GO:0006897)
Endosome
(GO:0005768)
External side of plasma membrane
(GO:0009897)
Extracellular matrix disassembly
(GO:0022617)
Flotillin complex
(GO:0016600)
Gaba-ergic synapse
(GO:0098982)
Glutamatergic synapse
(GO:0098978)
Ionotropic glutamate receptor binding
(GO:0035255)
Lamellipodium
(GO:0030027)
Membrane
(GO:0016020)
Membrane raft
(GO:0045121)
Microtubule organizing center
(GO:0005815)
Plasma membrane
(GO:0005886)
Plasma membrane raft
(GO:0044853)
Plasma membrane raft assembly
(GO:0044854)
Plasma membrane raft organization
(GO:0044857)
Positive regulation of canonical nf-kappab signal transduction
(GO:0043123)
Positive regulation of cell-cell adhesion mediated by cadherin
(GO:2000049)
Positive regulation of cell junction assembly
(GO:1901890)
Positive regulation of cytokine production
(GO:0001819)
Positive regulation of endocytosis
(GO:0045807)
Positive regulation of heterotypic cell-cell adhesion
(GO:0034116)
Positive regulation of interferon-beta production
(GO:0032728)
Positive regulation of myoblast fusion
(GO:1901741)
Positive regulation of protein binding
(GO:0032092)
Positive regulation of protein phosphorylation
(GO:0001934)
Positive regulation of skeletal muscle tissue development
(GO:0048643)
Positive regulation of synaptic transmission, dopaminergic
(GO:0032226)
Positive regulation of toll-like receptor 3 signaling pathway
(GO:0034141)
Presynapse
(GO:0098793)
Presynaptic active zone
(GO:0048786)
Protease binding
(GO:0002020)
Protein binding
(GO:0005515)
Protein kinase c signaling
(GO:0070528)
Protein localization to plasma membrane
(GO:0072659)
Protein stabilization
(GO:0050821)
Regulation of neurotransmitter uptake
(GO:0051580)
Regulation of receptor internalization
(GO:0002090)
Regulation of rho protein signal transduction
(GO:0035023)
Response to endoplasmic reticulum stress
(GO:0034976)
Sarcolemma
(GO:0042383)
Synapse
(GO:0045202)
Uropod
(GO:0001931)

Other Information

Proteins

Flotillin-1

Genular Protein ID: 399814603

Symbol: FLOT1_MOUSE

Name: Flotillin-1

UniProtKB Accession Codes:

O08917

Database IDs:

Citations:

PubMed ID: 9153235

Title: Flotillin and epidermal surface antigen define a new family of caveolae-associated integral membrane proteins.

PubMed ID: 9153235

DOI: 10.1074/jbc.272.21.13793

PubMed ID: 10212252

Title: Flotillins/cavatellins are differentially expressed in cells and tissues and form a hetero-oligomeric complex with caveolins in vivo. Characterization and epitope-mapping of a novel flotillin-1 monoclonal antibody probe.

PubMed ID: 10212252

DOI: 10.1074/jbc.274.18.12702

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

Sequence Information:

Length: 428
Mass: 47513
Checksum: 4B17C7EA1263F52C
Sequence:

MFFTCGPNEA MVVSGFCRSP PVMVAGGRVF VLPCIQQIQR ISLNTLTLNV KSEKVYTRHG 
VPISVTGIAQ VKIQGQNKEM LAAACQMFLG KTEAEIAHIA LETLEGHQRA IMAHMTVEEI 
YKDRQKFSEQ VFKVASSDLV NMGISVVSYT LKDIHDDQDY LHSLGKARTA QVQKDARIGE 
AEAKRDAGIR EAKAKQEKVS AQCLSEIEMA KAQRDYELKK ATYDIEVNTR RAQADLAYQL 
QVAKTKQQIE EQRVQVQVVE RAQQVAVQEQ EIARREKELE ARVRKPAEAE RYRLERLAEA 
EKAQLIMQAE AEAESVRMRG EAEAFAIGAR ARAEAEQMAK KAEAFQMYQE AAQLDMLLEK 
LPQVAEEISG PLTSANKITL VSSGSGTMGA AKVTGEVLDI LSRLPESVER LTGVSISQVN 
HNKPLRTA

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Flot1

Associated with

Other Information

Flotillin and epidermal surface antigen define a new family of caveolae-associated integral membrane proteins. PubMed ID: 9153235

Flotillins/cavatellins are differentially expressed in cells and tissues and form a hetero-oligomeric complex with caveolins in vivo. Characterization and epitope-mapping of a novel flotillin-1 monoclonal antibody probe. PubMed ID: 10212252

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

A tissue-specific atlas of mouse protein phosphorylation and expression. PubMed ID: 21183079

Database document:

PubMed ID: 9153235

PubMed ID: 10212252

PubMed ID: 15489334

PubMed ID: 21183079