Genular: Defining Cellular Identity and Function

Details for: Fnta

Gene ID: 14272

Symbol: Fnta

Ensembl ID: ENSMUSG00000015994

Description: farnesyltransferase, CAAX box, alpha

Associated with

Apoptosis
(R-MMU-109581)
Apoptotic cleavage of cellular proteins
(R-MMU-111465)
Apoptotic execution phase
(R-MMU-75153)
Inactivation, recovery and regulation of the phototransduction cascade
(R-MMU-2514859)
Mapk1/mapk3 signaling
(R-MMU-5684996)
Mapk family signaling cascades
(R-MMU-5683057)
Programmed cell death
(R-MMU-5357801)
Raf/map kinase cascade
(R-MMU-5673001)
Ras processing
(R-MMU-9648002)
Sensory perception
(R-MMU-9709957)
Signal transduction
(R-MMU-162582)
The phototransduction cascade
(R-MMU-2514856)
Visual phototransduction
(R-MMU-2187338)
Alpha-tubulin binding
(GO:0043014)
Caax-protein geranylgeranyltransferase activity
(GO:0004662)
Caax-protein geranylgeranyltransferase complex
(GO:0005953)
Cytoplasm
(GO:0005737)
Enzyme-linked receptor protein signaling pathway
(GO:0007167)
Heterocyclic compound binding
(GO:1901363)
Microtubule associated complex
(GO:0005875)
Microtubule binding
(GO:0008017)
Molecular adaptor activity
(GO:0060090)
Negative regulation of apoptotic process
(GO:0043066)
Negative regulation of nitric-oxide synthase biosynthetic process
(GO:0051771)
Peptide binding
(GO:0042277)
Positive regulation of cell cycle
(GO:0045787)
Positive regulation of cell population proliferation
(GO:0008284)
Positive regulation of deacetylase activity
(GO:0090045)
Positive regulation of nitric-oxide synthase biosynthetic process
(GO:0051770)
Positive regulation of rac protein signal transduction
(GO:0035022)
Positive regulation of skeletal muscle acetylcholine-gated channel clustering
(GO:1904395)
Positive regulation of tubulin deacetylation
(GO:0090044)
Prenyltransferase activity
(GO:0004659)
Protein farnesylation
(GO:0018343)
Protein farnesyltransferase activity
(GO:0004660)
Protein farnesyltransferase complex
(GO:0005965)
Protein geranylgeranylation
(GO:0018344)
Protein geranylgeranyltransferase activity
(GO:0004661)
Protein prenylation
(GO:0018342)
Protein prenyltransferase activity
(GO:0008318)
Rab geranylgeranyltransferase activity
(GO:0004663)
Receptor tyrosine kinase binding
(GO:0030971)
Response to cytokine
(GO:0034097)
Response to inorganic substance
(GO:0010035)
Response to organic cyclic compound
(GO:0014070)
Small molecule binding
(GO:0036094)
Transferase activity
(GO:0016740)
Zinc ion binding
(GO:0008270)

Other Information

Proteins

Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha

Genular Protein ID: 2185134865

Symbol: FNTA_MOUSE

Name: Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha

UniProtKB Accession Codes:

Q61239 Q921F7

Database IDs:

Citations:

PubMed ID: 7590362

Title: Cloning and sequencing of the murine farnesyltransferase alpha-encoding cDNA from a cell line which expresses the human papillomavirus type-16 E6 gene.

PubMed ID: 7590362

DOI: 10.1016/0378-1119(95)00445-c

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 14622576

Title: Implication of geranylgeranyltransferase I in synapse formation.

PubMed ID: 14622576

DOI: 10.1016/s0896-6273(03)00695-0

PubMed ID: 17652517

Title: HIV protease inhibitors block the zinc metalloproteinase ZMPSTE24 and lead to an accumulation of prelamin A in cells.

PubMed ID: 17652517

DOI: 10.1073/pnas.0704212104

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

Sequence Information:

Length: 377
Mass: 44013
Checksum: F3D60B9899F36D66
Sequence:

MAATEGVGES AAGGEPGQPE QPPPPPPPPP AQQPQEEEMA AEAGEAAASP MDDGFLSLDS 
PTYVLYRDRA EWADIDPVPQ NDGPNPVVQI IYSEKFRDVY DYFRAVLQRD ERSERAFKLT 
RDAIELNAAN YTVWHFRRVL LRSLQKDLQE EMNYITAIIE EQPKNYQVWH HRRVLVEWLK 
DPSQELEFIA DILSQDAKNY HAWQHRQWVI QEFRLWDNEL QYVDQLLKED VRNNSVWNQR 
HFVISNTTGY SDRAVLEREV QYTLEMIKLV PHNESAWNYL KGILQDRGLS RYPNLLNQLL 
DLQPSHSSPY LIAFLVDVYE DMLENQCDNK EDILNKALEL CEILAKEKDT IRKEYWRYIG 
RSLQSKHCRE SDIPASV

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Fnta

Associated with

Other Information

Cloning and sequencing of the murine farnesyltransferase alpha-encoding cDNA from a cell line which expresses the human papillomavirus type-16 E6 gene. PubMed ID: 7590362

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Implication of geranylgeranyltransferase I in synapse formation. PubMed ID: 14622576