Details for: Fpgs

Gene ID: 14287

Symbol: Fpgs

Ensembl ID: ENSMUSG00000009566

Description: folylpolyglutamyl synthetase

Associated with

Other Information

Genular Protein ID: 1872474990

Symbol: FOLC_MOUSE

Name: Folylpolyglutamate synthase, mitochondrial

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 7592937

Title: Different antifolate-resistant L1210 cell variants with either increased or decreased folylpolyglutamate synthetase gene expression at the level of mRNA transcription.

PubMed ID: 7592937

DOI: 10.1074/jbc.270.45.26918

PubMed ID: 8605241

Title: Molecular cloning of murine folylpoly-gamma-glutamate synthetase.

PubMed ID: 8605241

DOI: 10.1016/0167-4781(95)00193-x

PubMed ID: 8798611

Title: Organization and alternate splicing of the murine folylpolyglutamate synthetase gene. Different splice variants in L1210 cells encode mitochondrial or cytosolic forms of the enzyme.

PubMed ID: 8798611

DOI: 10.1074/jbc.271.39.23820

PubMed ID: 9038166

Title: Additional organizational features of the murine folylpolyglutamate synthetase gene. Two remotely situated exons encoding an alternate 5' end and proximal open rea ding frame under the control of a second promoter.

PubMed ID: 9038166

DOI: 10.1074/jbc.272.9.5587

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 19468303

Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.

PubMed ID: 19468303

DOI: 10.1371/journal.pbio.1000112

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 6548641

Title: Mammalian folyl polyglutamate synthetase: partial purification and properties of the mouse liver enzyme.

PubMed ID: 6548641

DOI: 10.1021/bi00315a011

PubMed ID: 10626793

Title: Tissue-specific expression of functional isoforms of mouse folypoly-gamma-glutamae synthetase: a basis for targeting folate antimetabolites.

PubMed ID: 10626793

PubMed ID: 11772020

Title: Mouse folylpoly-gamma-glutamate synthetase isoforms respond differently to feedback inhibition by folylpolyglutamate cofactors.

PubMed ID: 11772020

DOI: 10.1021/bi015644d

PubMed ID: 17998333

Title: A mouse gene that coordinates epigenetic controls and transcriptional interference to achieve tissue-specific expression.

PubMed ID: 17998333

DOI: 10.1128/mcb.01088-07

Sequence Information:

  • Length: 587
  • Mass: 64955
  • Checksum: B93261CBA110CA41
  • Sequence:
  • MSWARSRLCS TLSLAAVSAR GATTEGAARR GMSAWPAPQE PGMEYQDAVR TLNTLQTNAS 
    YLEQVKRQRS DPQAQLEAME MYLARSGLQV EDLNRLNIIH VTGTKGKGST CAFTERILRN 
    YGLKTGFFSS PHMVQVRERI RINGKPISPE LFTKHFWCLY NQLEEFKDDS HVSMPSYFRF 
    LTLMAFHVFL QEKVDLAVVE VGIGGAFDCT NIIRKPVVCG VSSLGIDHTS LLGDTVEKIA 
    WQKGGIFKPG VPAFTVVQPE GPLAVLRDRA QQIGCPLYLC PPLEALEEVG LPLSLGLEGA 
    HQRSNAALAL QLAHCWLERQ DHQDIQELKV SRPSIRWQLP LAPVFRPTPH MRRGLRDTVW 
    PGRTQILQRG PLTWYLDGAH TTSSVQACVH WYRQSLERSK RTDGGSEVHI LLFNSTGDRD 
    SAALLKLLQP CQFDYAVFCP NVTEVSSIGN ADQQNFTVTL DQVLLRCLQH QQHWNGLAEK 
    QASSNLWSSC GPDPAGPGSL LLAPHPPQPT RTSSLVFSCI SHALLWISQG RDPIFQPQSL 
    PRNLLNHPTA NSGASILREA AAIHVLVTGS LHLVGGVLKL LDPSMSQ

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.