Genular: Defining Cellular Identity and Function

Details for: Fpr1

Gene ID: 14293

Symbol: Fpr1

Ensembl ID: ENSMUSG00000045551

Description: formyl peptide receptor 1

Associated with

Class a/1 (rhodopsin-like receptors)
(R-MMU-373076)
Formyl peptide receptors bind formyl peptides and many other ligands
(R-MMU-444473)
G alpha (i) signalling events
(R-MMU-418594)
Gpcr downstream signalling
(R-MMU-388396)
Gpcr ligand binding
(R-MMU-500792)
Immune system
(R-MMU-168256)
Innate immune system
(R-MMU-168249)
Neutrophil degranulation
(R-MMU-6798695)
Peptide ligand-binding receptors
(R-MMU-375276)
Signaling by gpcr
(R-MMU-372790)
Chemotaxis
(GO:0006935)
Complement receptor activity
(GO:0004875)
Complement receptor mediated signaling pathway
(GO:0002430)
Cytoplasm
(GO:0005737)
G protein-coupled receptor activity
(GO:0004930)
G protein-coupled receptor binding
(GO:0001664)
G protein-coupled receptor signaling pathway
(GO:0007186)
Inflammatory response
(GO:0006954)
Membrane
(GO:0016020)
N-formyl peptide receptor activity
(GO:0004982)
Phospholipase c-activating g protein-coupled receptor signaling pathway
(GO:0007200)
Plasma membrane
(GO:0005886)
Positive regulation of cytosolic calcium ion concentration
(GO:0007204)
Rage receptor binding
(GO:0050786)
Scavenger receptor binding
(GO:0005124)
Signal transduction
(GO:0007165)

Other Information

Proteins

fMet-Leu-Phe receptor

Genular Protein ID: 3988949162

Symbol: FPR1_MOUSE

Name: fMet-Leu-Phe receptor

UniProtKB Accession Codes:

P33766 Q3UV01

Database IDs:

Citations:

PubMed ID: 8244972

Title: Species and subtype variants of the N-formyl peptide chemotactic receptor reveal multiple important functional domains.

PubMed ID: 8244972

DOI: 10.1016/s0021-9258(19)74405-6

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 17084101

Title: Formyl peptide receptors: a promiscuous subfamily of G protein-coupled receptors controlling immune responses.

PubMed ID: 17084101

DOI: 10.1016/j.cytogfr.2006.09.009

PubMed ID: 19497865

Title: Formyl peptide receptors are candidate chemosensory receptors in the vomeronasal organ.

PubMed ID: 19497865

DOI: 10.1073/pnas.0904464106

Sequence Information:

Length: 364
Mass: 40327
Checksum: 2F59193CF1D74DB2
Sequence:

MDTNMSLLMN KSAVNLMNVS GSTQSVSAGY IVLDVFSYLI FAVTFVLGVL GNGLVIWVAG 
FRMKHTVTTI SYLNLAIADF CFTSTLPFYI ASMVMGGHWP FGWFMCKFIY TVIDINLFGS 
VFLIALIALD RCICVLHPVW AQNHRTVSLA KKVIIVPWIC AFLLTLPVII RLTTVPNSRL 
GPGKTACTFD FSPWTKDPVE KRKVAVTMLT VRGIIRFIIG FSTPMSIVAI CYGLITTKIH 
RQGLIKSSRP LRVLSFVVAA FFLCWCPFQV VALISTIQVR ERLKNMTPGI VTALKITSPL 
AFFNSCLNPM LYVFMGQDFR ERLIHSLPAS LERALTEDSA QTSDTGTNLG TNSTSLSENT 
LNAM

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Fpr1

Associated with

Other Information

Species and subtype variants of the N-formyl peptide chemotactic receptor reveal multiple important functional domains. PubMed ID: 8244972

The transcriptional landscape of the mammalian genome. PubMed ID: 16141072

Formyl peptide receptors: a promiscuous subfamily of G protein-coupled receptors controlling immune responses. PubMed ID: 17084101

Formyl peptide receptors are candidate chemosensory receptors in the vomeronasal organ. PubMed ID: 19497865

Database document:

PubMed ID: 8244972

PubMed ID: 16141072

PubMed ID: 17084101

PubMed ID: 19497865