Genular: Defining Cellular Identity and Function

Details for: Frat1

Gene ID: 14296

Symbol: Frat1

Ensembl ID: ENSMUSG00000067199

Description: frequently rearranged in advanced T cell lymphomas

Associated with

Beta-catenin phosphorylation cascade
(R-MMU-196299)
Degradation of beta-catenin by the destruction complex
(R-MMU-195253)
Disassembly of the destruction complex and recruitment of axin to the membrane
(R-MMU-4641262)
Signaling by wnt
(R-MMU-195721)
Signal transduction
(R-MMU-162582)
Tcf dependent signaling in response to wnt
(R-MMU-201681)
Beta-catenin destruction complex disassembly
(GO:1904886)
Canonical wnt signaling pathway
(GO:0060070)
Cytoplasm
(GO:0005737)
Cytosol
(GO:0005829)
Embryonic axis specification
(GO:0000578)
Intracellular membrane-bounded organelle
(GO:0043231)
Molecular function inhibitor activity
(GO:0140678)
Nucleus
(GO:0005634)
Positive regulation of canonical wnt signaling pathway
(GO:0090263)
Protein binding
(GO:0005515)
Protein export from nucleus
(GO:0006611)
Regulation of protein export from nucleus
(GO:0046825)
Wnt signaling pathway
(GO:0016055)

Other Information

Proteins

Proto-oncogene FRAT1

Genular Protein ID: 3208879058

Symbol: FRAT1_MOUSE

Name: Proto-oncogene FRAT1

UniProtKB Accession Codes:

P70339

Database IDs:

Citations:

PubMed ID: 9034327

Title: Activation of a novel proto-oncogene, Frat1, contributes to progression of mouse T-cell lymphomas.

PubMed ID: 9034327

DOI: 10.1093/emboj/16.3.441

PubMed ID: 15073180

Title: Characterization and functional analysis of the murine Frat2 gene.

PubMed ID: 15073180

DOI: 10.1074/jbc.m400439200

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

Sequence Information:

Length: 274
Mass: 28875
Checksum: 1C0482997EA95323
Sequence:

MPCRREEEEE AGDEAEGEED DDSFLLLQQS VTLGGSTDVD QLIVQIGETL QLDAAHDRPA 
SPCAAPGPPP PQVLAALPAD KTGTPARRLL RPTGSAETGN PAPPGAVRCV LGERGRVRGR 
SAPYCVAEIS PGASALPQQP GLDGPPGTGK LSTPQPLSGP CRRGWLRNAA ASRRLQQRRG 
SQPETRTGDD DDPHRLLQQL VLSGNLIKEA VRRLHSRQLQ LHAKLPAHPF LGPLSAPVHE 
PPSPGSPRAA CSDPGAFMGR AQLRTGDDLL VPGS

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.