Details for: PARP4
Associated with
Cells (max top 100)
(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: polychromatophilic erythroblast (CL0000550)
Fold Change: 213.9249
Cell Significance Index: -33.2800 - Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
Fold Change: 124.8603
Cell Significance Index: -31.6700 - Cell Name: embryonic stem cell (CL0002322)
Fold Change: 87.8510
Cell Significance Index: -36.1900 - Cell Name: mucosal type mast cell (CL0000485)
Fold Change: 69.7834
Cell Significance Index: -28.3500 - Cell Name: peripheral blood mononuclear cell (CL2000001)
Fold Change: 63.4933
Cell Significance Index: -32.6600 - Cell Name: ciliated cell of the bronchus (CL0002332)
Fold Change: 29.7358
Cell Significance Index: -28.3900 - Cell Name: orthochromatic erythroblast (CL0000552)
Fold Change: 27.4016
Cell Significance Index: -33.7900 - Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
Fold Change: 12.5016
Cell Significance Index: -33.4900 - Cell Name: epidermal Langerhans cell (CL0002457)
Fold Change: 9.9699
Cell Significance Index: -21.8200 - Cell Name: stromal cell of bone marrow (CL0010001)
Fold Change: 8.6213
Cell Significance Index: -34.0200 - Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
Fold Change: 8.4260
Cell Significance Index: -25.8800 - Cell Name: epithelial cell of small intestine (CL0002254)
Fold Change: 3.3072
Cell Significance Index: 537.8800 - Cell Name: intestinal crypt stem cell of colon (CL0009043)
Fold Change: 1.9654
Cell Significance Index: 213.7800 - Cell Name: cortical cell of adrenal gland (CL0002097)
Fold Change: 1.6178
Cell Significance Index: 43.3500 - Cell Name: preadipocyte (CL0002334)
Fold Change: 1.4874
Cell Significance Index: 29.0300 - Cell Name: neoplastic cell (CL0001063)
Fold Change: 1.4534
Cell Significance Index: 288.4400 - Cell Name: paneth cell of colon (CL0009009)
Fold Change: 1.2914
Cell Significance Index: 19.3500 - Cell Name: umbrella cell of urothelium (CL4030056)
Fold Change: 1.2803
Cell Significance Index: 11.7900 - Cell Name: centrilobular region hepatocyte (CL0019029)
Fold Change: 1.2194
Cell Significance Index: 20.5400 - Cell Name: bladder urothelial cell (CL1001428)
Fold Change: 1.1288
Cell Significance Index: 58.6400 - Cell Name: enteroendocrine cell of small intestine (CL0009006)
Fold Change: 1.1237
Cell Significance Index: 28.0900 - Cell Name: intermediate cell of urothelium (CL4030055)
Fold Change: 1.0924
Cell Significance Index: 196.9300 - Cell Name: enterocyte of epithelium of small intestine (CL1000334)
Fold Change: 1.0591
Cell Significance Index: 30.5200 - Cell Name: tuft cell of colon (CL0009041)
Fold Change: 1.0455
Cell Significance Index: 944.0100 - Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
Fold Change: 0.9944
Cell Significance Index: 27.7900 - Cell Name: basal cell of urothelium (CL1000486)
Fold Change: 0.9317
Cell Significance Index: 114.5700 - Cell Name: retinal progenitor cell (CL0002672)
Fold Change: 0.7934
Cell Significance Index: 44.5200 - Cell Name: enterocyte of epithelium of large intestine (CL0002071)
Fold Change: 0.7208
Cell Significance Index: 32.6700 - Cell Name: peg cell (CL4033014)
Fold Change: 0.7120
Cell Significance Index: 16.4500 - Cell Name: tuft cell of small intestine (CL0009080)
Fold Change: 0.7018
Cell Significance Index: 7.0800 - Cell Name: fibro/adipogenic progenitor cell (CL0009099)
Fold Change: 0.6675
Cell Significance Index: 33.7300 - Cell Name: GABAergic interneuron (CL0011005)
Fold Change: 0.6387
Cell Significance Index: 441.7400 - Cell Name: lung endothelial cell (CL1001567)
Fold Change: 0.4586
Cell Significance Index: 23.8900 - Cell Name: cell in vitro (CL0001034)
Fold Change: 0.4517
Cell Significance Index: 246.7000 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: 0.3545
Cell Significance Index: 27.2000 - Cell Name: enteroendocrine cell of colon (CL0009042)
Fold Change: 0.2907
Cell Significance Index: 55.3200 - Cell Name: early pro-B cell (CL0002046)
Fold Change: 0.2564
Cell Significance Index: 16.5400 - Cell Name: colon goblet cell (CL0009039)
Fold Change: 0.2136
Cell Significance Index: 21.1300 - Cell Name: small intestine goblet cell (CL1000495)
Fold Change: 0.1764
Cell Significance Index: 6.2000 - Cell Name: hair follicular keratinocyte (CL2000092)
Fold Change: 0.1657
Cell Significance Index: 73.2600 - Cell Name: anterior lens cell (CL0002223)
Fold Change: 0.1558
Cell Significance Index: 287.2800 - Cell Name: cardiac endothelial cell (CL0010008)
Fold Change: 0.1252
Cell Significance Index: 1.8000 - Cell Name: stromal cell of ovary (CL0002132)
Fold Change: 0.1207
Cell Significance Index: 16.5800 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: 0.0945
Cell Significance Index: 177.9500 - Cell Name: lens epithelial cell (CL0002224)
Fold Change: 0.0939
Cell Significance Index: 144.5900 - Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
Fold Change: 0.0873
Cell Significance Index: 1.8600 - Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
Fold Change: 0.0677
Cell Significance Index: 3.1800 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: 0.0649
Cell Significance Index: 18.6700 - Cell Name: pancreatic acinar cell (CL0002064)
Fold Change: 0.0454
Cell Significance Index: 7.7500 - Cell Name: ciliary muscle cell (CL1000443)
Fold Change: 0.0431
Cell Significance Index: 19.5500 - Cell Name: secondary lens fiber (CL0002225)
Fold Change: 0.0425
Cell Significance Index: 57.8200 - Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: 0.0358
Cell Significance Index: 22.7200 - Cell Name: leptomeningeal cell (CL0000708)
Fold Change: 0.0318
Cell Significance Index: 0.6800 - Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: 0.0300
Cell Significance Index: 10.7500 - Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
Fold Change: 0.0076
Cell Significance Index: 0.1400 - Cell Name: tonsil germinal center B cell (CL2000006)
Fold Change: -0.0092
Cell Significance Index: -1.0800 - Cell Name: pancreatic PP cell (CL0002275)
Fold Change: -0.0115
Cell Significance Index: -7.1700 - Cell Name: fibroblast of cardiac tissue (CL0002548)
Fold Change: -0.0129
Cell Significance Index: -0.1800 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: -0.0190
Cell Significance Index: -3.8100 - Cell Name: pancreatic A cell (CL0000171)
Fold Change: -0.0190
Cell Significance Index: -14.1100 - Cell Name: pulmonary alveolar epithelial cell (CL0000322)
Fold Change: -0.0312
Cell Significance Index: -23.6000 - Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
Fold Change: -0.0330
Cell Significance Index: -24.2300 - Cell Name: pigmented ciliary epithelial cell (CL0002303)
Fold Change: -0.0331
Cell Significance Index: -4.8100 - Cell Name: type B pancreatic cell (CL0000169)
Fold Change: -0.0450
Cell Significance Index: -25.4000 - Cell Name: abnormal cell (CL0001061)
Fold Change: -0.0524
Cell Significance Index: -5.3500 - Cell Name: pancreatic D cell (CL0000173)
Fold Change: -0.0915
Cell Significance Index: -19.2800 - Cell Name: sebum secreting cell (CL0000317)
Fold Change: -0.0916
Cell Significance Index: -6.4800 - Cell Name: odontoblast (CL0000060)
Fold Change: -0.1133
Cell Significance Index: -14.5300 - Cell Name: acinar cell of salivary gland (CL0002623)
Fold Change: -0.1542
Cell Significance Index: -7.1900 - Cell Name: forebrain neuroblast (CL1000042)
Fold Change: -0.1620
Cell Significance Index: -9.9600 - Cell Name: lactocyte (CL0002325)
Fold Change: -0.1670
Cell Significance Index: -21.5800 - Cell Name: epithelial cell of stomach (CL0002178)
Fold Change: -0.1673
Cell Significance Index: -19.5000 - Cell Name: paneth cell of epithelium of small intestine (CL1000343)
Fold Change: -0.1685
Cell Significance Index: -3.6500 - Cell Name: conjunctival epithelial cell (CL1000432)
Fold Change: -0.1759
Cell Significance Index: -2.4000 - Cell Name: periportal region hepatocyte (CL0019026)
Fold Change: -0.1762
Cell Significance Index: -2.6000 - Cell Name: pancreatic ductal cell (CL0002079)
Fold Change: -0.1795
Cell Significance Index: -20.5700 - Cell Name: Hofbauer cell (CL3000001)
Fold Change: -0.1925
Cell Significance Index: -1.5700 - Cell Name: pancreatic endocrine cell (CL0008024)
Fold Change: -0.2083
Cell Significance Index: -23.7800 - Cell Name: placental villous trophoblast (CL2000060)
Fold Change: -0.2161
Cell Significance Index: -5.7700 - Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
Fold Change: -0.2601
Cell Significance Index: -27.0800 - Cell Name: eye photoreceptor cell (CL0000287)
Fold Change: -0.3251
Cell Significance Index: -20.4900 - Cell Name: neutrophil progenitor cell (CL0000834)
Fold Change: -0.3335
Cell Significance Index: -8.9200 - Cell Name: basal cell of prostate epithelium (CL0002341)
Fold Change: -0.3362
Cell Significance Index: -9.1500 - Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
Fold Change: -0.3587
Cell Significance Index: -26.7300 - Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
Fold Change: -0.3594
Cell Significance Index: -28.4700 - Cell Name: transit amplifying cell of colon (CL0009011)
Fold Change: -0.3783
Cell Significance Index: -12.1200 - Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
Fold Change: -0.3977
Cell Significance Index: -11.6800 - Cell Name: intestinal tuft cell (CL0019032)
Fold Change: -0.4177
Cell Significance Index: -25.6100 - Cell Name: endothelial cell of placenta (CL0009092)
Fold Change: -0.4187
Cell Significance Index: -2.5300 - Cell Name: hippocampal granule cell (CL0001033)
Fold Change: -0.5019
Cell Significance Index: -33.7500 - Cell Name: glycinergic neuron (CL1001509)
Fold Change: -0.6445
Cell Significance Index: -33.8400 - Cell Name: foveolar cell of stomach (CL0002179)
Fold Change: -0.6534
Cell Significance Index: -4.2600 - Cell Name: mesenchymal cell (CL0008019)
Fold Change: -0.6555
Cell Significance Index: -10.9700 - Cell Name: corneal epithelial cell (CL0000575)
Fold Change: -0.6589
Cell Significance Index: -9.3800 - Cell Name: stratified epithelial cell (CL0000079)
Fold Change: -0.6704
Cell Significance Index: -24.6100 - Cell Name: pro-T cell (CL0000827)
Fold Change: -0.7171
Cell Significance Index: -18.3200 - Cell Name: granulosa cell (CL0000501)
Fold Change: -0.7287
Cell Significance Index: -19.1600 - Cell Name: indirect pathway medium spiny neuron (CL4023029)
Fold Change: -0.7400
Cell Significance Index: -32.7300 - Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
Fold Change: -0.7450
Cell Significance Index: -25.8900 - Cell Name: cardiac muscle cell (CL0000746)
Fold Change: -0.7519
Cell Significance Index: -11.1000
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 3982475008
Symbol: PARP4_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 10477748
Title: The 193 kDa vault protein, VPARP, is a novel poly(ADP-ribose) polymerase.
PubMed ID: 10477748
PubMed ID: 10644454
Title: Identification of a novel gene (ADPRTL1) encoding a potential poly(ADP-ribosyl)transferase protein.
PubMed ID: 10644454
PubMed ID: 8724849
Title: Prediction of the coding sequences of unidentified human genes. V. The coding sequences of 40 new genes (KIAA0161-KIAA0200) deduced by analysis of cDNA clones from human cell line KG-1.
PubMed ID: 8724849
PubMed ID: 15057823
Title: The DNA sequence and analysis of human chromosome 13.
PubMed ID: 15057823
DOI: 10.1038/nature02379
PubMed ID: 10100603
Title: The nuclear protein PH5P of the inter-alpha-inhibitor superfamily: a missing link between poly(ADP-ribose)polymerase and the inter-alpha-inhibitor family and a novel actor of DNA repair?
PubMed ID: 10100603
PubMed ID: 10551828
Title: Vaults and telomerase share a common subunit, TEP1.
PubMed ID: 10551828
PubMed ID: 15169895
Title: Vault poly(ADP-ribose) polymerase is associated with mammalian telomerase and is dispensable for telomerase function and vault structure in vivo.
PubMed ID: 15169895
PubMed ID: 18669648
Title: A quantitative atlas of mitotic phosphorylation.
PubMed ID: 18669648
PubMed ID: 20068231
Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.
PubMed ID: 20068231
PubMed ID: 20106667
Title: Toward a unified nomenclature for mammalian ADP-ribosyltransferases.
PubMed ID: 20106667
PubMed ID: 21269460
Title: Initial characterization of the human central proteome.
PubMed ID: 21269460
PubMed ID: 23186163
Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.
PubMed ID: 23186163
DOI: 10.1021/pr300630k
PubMed ID: 24275569
Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.
PubMed ID: 24275569
PubMed ID: 25043379
Title: Family-wide analysis of poly(ADP-ribose) polymerase activity.
PubMed ID: 25043379
DOI: 10.1038/ncomms5426
PubMed ID: 24129315
Title: Immunoaffinity enrichment and mass spectrometry analysis of protein methylation.
PubMed ID: 24129315
Sequence Information:
- Length: 1724
- Mass: 192595
- Checksum: DCA1DD4C001EA22F
- Sequence:
MVMGIFANCI FCLKVKYLPQ QQKKKLQTDI KENGGKFSFS LNPQCTHIIL DNADVLSQYQ LNSIQKNHVH IANPDFIWKS IREKRLLDVK NYDPYKPLDI TPPPDQKASS SEVKTEGLCP DSATEEEDTV ELTEFGMQNV EIPHLPQDFE VAKYNTLEKV GMEGGQEAVV VELQCSRDSR DCPFLISSHF LLDDGMETRR QFAIKKTSED ASEYFENYIE ELKKQGFLLR EHFTPEATQL ASEQLQALLL EEVMNSSTLS QEVSDLVEMI WAEALGHLEH MLLKPVNRIS LNDVSKAEGI LLLVKAALKN GETAEQLQKM MTEFYRLIPH KGTMPKEVNL GLLAKKADLC QLIRDMVNVC ETNLSKPNPP SLAKYRALRC KIEHVEQNTE EFLRVRKEVL QNHHSKSPVD VLQIFRVGRV NETTEFLSKL GNVRPLLHGS PVQNIVGILC RGLLLPKVVE DRGVQRTDVG NLGSGIYFSD SLSTSIKYSH PGETDGTRLL LICDVALGKC MDLHEKDFSL TEAPPGYDSV HGVSQTASVT TDFEDDEFVV YKTNQVKMKY IIKFSMPGDQ IKDFHPSDHT ELEEYRPEFS NFSKVEDYQL PDAKTSSSTK AGLQDASGNL VPLEDVHIKG RIIDTVAQVI VFQTYTNKSH VPIEAKYIFP LDDKAAVCGF EAFINGKHIV GEIKEKEEAQ QEYLEAVTQG HGAYLMSQDA PDVFTVSVGN LPPKAKVLIK ITYITELSIL GTVGVFFMPA TVAPWQQDKA LNENLQDTVE KICIKEIGTK QSFSLTMSIE MPYVIEFIFS DTHELKQKRT DCKAVISTME GSSLDSSGFS LHIGLSAAYL PRMWVEKHPE KESEACMLVF QPDLDVDLPD LASESEVIIC LDCSSSMEGV TFLQAKQIAL HALSLVGEKQ KVNIIQFGTG YKELFSYPKH ITSNTMAAEF IMSATPTMGN TDFWKTLRYL SLLYPARGSR NILLVSDGHL QDESLTLQLV KRSRPHTRLF ACGIGSTANR HVLRILSQCG AGVFEYFNAK SKHSWRKQIE DQMTRLCSPS CHSVSVKWQQ LNPDVPEALQ APAQVPSLFL NDRLLVYGFI PHCTQATLCA LIQEKEFRTM VSTTELQKTT GTMIHKLAAR ALIRDYEDGI LHENETSHEM KKQTLKSLII KLSKENSLIT QFTSFVAVEK RDENESPFPD IPKVSELIAK EDVDFLPYMS WQGEPQEAVR NQSLLASSEW PELRLSKRKH RKIPFSKRKM ELSQPEVSED FEEDGLGVLP AFTSNLERGG VEKLLDLSWT ESCKPTATEP LFKKVSPWET STSSFFPILA PAVGSYLPPT ARAHSPASLS FASYRQVASF GSAAPPRQFD ASQFSQGPVP GTCADWIPQS ASCPTGPPQN PPSSPYCGIV FSGSSLSSAQ SAPLQHPGGF TTRPSAGTFP ELDSPQLHFS LPTDPDPIRG FGSYHPSASS PFHFQPSAAS LTANLRLPMA SALPEALCSQ SRTTPVDLCL LEESVGSLEG SRCPVFAFQS SDTESDELSE VLQDSCFLQI KCDTKDDSIL CFLEVKEEDE IVCIQHWQDA VPWTELLSLQ TEDGFWKLTP ELGLILNLNT NGLHSFLKQK GIQSLGVKGR ECLLDLIATM LVLQFIRTRL EKEGIVFKSL MKMDDASISR NIPWAFEAIK QASEWVRRTE GQYPSICPRL ELGNDWDSAT KQLLGLQPIS TVSPLHRVLH YSQG
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.