Genular: Defining Cellular Identity and Function

Details for: Fshr

Gene ID: 14309

Symbol: Fshr

Ensembl ID: ENSMUSG00000032937

Description: follicle stimulating hormone receptor

Associated with

Class a/1 (rhodopsin-like receptors)
(R-MMU-373076)
G alpha (s) signalling events
(R-MMU-418555)
Gpcr downstream signalling
(R-MMU-388396)
Gpcr ligand binding
(R-MMU-500792)
Hormone ligand-binding receptors
(R-MMU-375281)
Signaling by gpcr
(R-MMU-372790)
Activation of adenylate cyclase activity
(GO:0007190)
Adenylate cyclase-activating g protein-coupled receptor signaling pathway
(GO:0007189)
Adenylate cyclase-inhibiting g protein-coupled receptor signaling pathway
(GO:0007193)
Adenylate cyclase-modulating g protein-coupled receptor signaling pathway
(GO:0007188)
Basement membrane organization
(GO:0071711)
Cell surface
(GO:0009986)
Cellular response to follicle-stimulating hormone stimulus
(GO:0071372)
Endosome
(GO:0005768)
Follicle-stimulating hormone receptor activity
(GO:0004963)
Follicle-stimulating hormone signaling pathway
(GO:0042699)
G protein-coupled peptide receptor activity
(GO:0008528)
G protein-coupled receptor activity
(GO:0004930)
G protein-coupled receptor signaling pathway
(GO:0007186)
Hormone-mediated signaling pathway
(GO:0009755)
Intracellular water homeostasis
(GO:0009992)
Locomotory behavior
(GO:0007626)
Male gonad development
(GO:0008584)
Membrane
(GO:0016020)
Negative regulation of bone resorption
(GO:0045779)
Neuron projection development
(GO:0031175)
Ovarian follicle development
(GO:0001541)
Ovulation cycle process
(GO:0022602)
Peptide hormone binding
(GO:0017046)
Phospholipase c-activating g protein-coupled receptor signaling pathway
(GO:0007200)
Plasma membrane
(GO:0005886)
Positive regulation of erk1 and erk2 cascade
(GO:0070374)
Positive regulation of intracellular estrogen receptor signaling pathway
(GO:0033148)
Positive regulation of phosphatidylinositol 3-kinase/protein kinase b signal transduction
(GO:0051897)
Primary ovarian follicle growth
(GO:0001545)
Protein-hormone receptor activity
(GO:0016500)
Receptor complex
(GO:0043235)
Regulation of acetylcholine metabolic process
(GO:0060408)
Regulation of chromosome organization
(GO:0033044)
Regulation of hormone metabolic process
(GO:0032350)
Regulation of intracellular estrogen receptor signaling pathway
(GO:0033146)
Regulation of mapk cascade
(GO:0043408)
Regulation of osteoclast differentiation
(GO:0045670)
Regulation of platelet-derived growth factor receptor signaling pathway
(GO:0010640)
Regulation of protein kinase a signaling
(GO:0010738)
Regulation of protein phosphorylation
(GO:0001932)
Regulation of systemic arterial blood pressure
(GO:0003073)
Sertoli cell development
(GO:0060009)
Sertoli cell proliferation
(GO:0060011)
Signal transduction
(GO:0007165)
Spermatid development
(GO:0007286)
Spermatogenesis
(GO:0007283)
Sperm dna condensation
(GO:0035092)
Transcytosis
(GO:0045056)
Uterus development
(GO:0060065)

Other Information

Proteins

Follicle-stimulating hormone receptor

Genular Protein ID: 2616681093

Symbol: FSHR_MOUSE

Name: Follicle-stimulating hormone receptor

UniProtKB Accession Codes:

P35378 Q9D4C2 Q9QWV8

Database IDs:

Citations:

PubMed ID: 10330114

Title: Molecular cloning of the mouse follicle-stimulating hormone receptor complementary deoxyribonucleic acid: functional expression of alternatively spliced variants and receptor inactivation by a C566T transition in exon 7 of the coding sequence.

PubMed ID: 10330114

DOI: 10.1095/biolreprod60.6.1515

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 1459341

Title: The murine luteinizing hormone and follicle-stimulating hormone receptor genes: transcription initiation sites, putative promoter sequences and promoter activity.

PubMed ID: 1459341

DOI: 10.1016/0303-7207(92)90009-u

Sequence Information:

Length: 692
Mass: 77769
Checksum: 4B57229180563A44
Sequence:

MALLLVSLLA FLGSGSGCHH WLCHCSNRVF LCQDSKVTEI PPDLPRNAIE LRFVLTKLRV 
IPKGSFSGFG DLEKIEISQN DVLEVIEADV FSNLPNLHEI RIEKANNLLY INPEAFQNLP 
SLRYLLISNT GIKHLPAFHK IQSLQKVLLD IQDNINIHII ARNSFMGLSF ESVILWLNKN 
GIQEIHNCAF NGTQLDELNL SDNNNLEELP DDVFQGASGP VVLDISRTKV YSLPNHGLEN 
LKKLRARSTY RLKKLPSLDK FVMLIEASLT YPSHCCAFAN WRRQTSELHP ICNKSISRQD 
IDDMTQPGDQ RVSLVDDEPS YGKGSDMLYS EFDYDLCNEF VDVTCSPKPD AFNPCEDIMG 
YNILRVLIWF ISILAITGNT TVLVVLTTSQ YKLTVPRFLM CNLAFADLCI GIYLLLIASV 
DIHTKSQYHN YAIDWQTGAG CDAAGFFTVF ASELSVYTLA AITLERWHTI THAMQLECKV 
QLCHAASIMV LGWAFAFAAA LFPIFGISSY MKVSICLPMD IDSPLSQLYV MALLVLNALA 
FVVICGCYTH IYLTVRNPNI VSSSRDTKIA KRMATLIFTD FLCMAPILFF AISASLKVPL 
ITVSKAKILL VLFYPINSCA NPFLYAIFTK NFRRDFFVLM SKFGCYEVQA QIYKTETSSI 
THNFHSRKNP CSSAPRVTNS YVLVPLNHSV QN

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.