Genular: Defining Cellular Identity and Function

Details for: Fth1

Gene ID: 14319

Symbol: Fth1

Ensembl ID: ENSMUSG00000024661

Description: ferritin heavy polypeptide 1

Associated with

Golgi associated vesicle biogenesis
(R-MMU-432722)
Immune system
(R-MMU-168256)
Innate immune system
(R-MMU-168249)
Iron uptake and transport
(R-MMU-917937)
Membrane trafficking
(R-MMU-199991)
Neutrophil degranulation
(R-MMU-6798695)
Trans-golgi network vesicle budding
(R-MMU-199992)
Transport of small molecules
(R-MMU-382551)
Vesicle-mediated transport
(R-MMU-5653656)
Autolysosome
(GO:0044754)
Cytoplasm
(GO:0005737)
Cytosol
(GO:0005829)
Endocytic vesicle lumen
(GO:0071682)
Extracellular region
(GO:0005576)
Ferric iron binding
(GO:0008199)
Ferrous iron binding
(GO:0008198)
Ferroxidase activity
(GO:0004322)
Identical protein binding
(GO:0042802)
Intracellular iron ion homeostasis
(GO:0006879)
Intracellular sequestering of iron ion
(GO:0006880)
Iron ion binding
(GO:0005506)
Iron ion sequestering activity
(GO:0140315)
Iron ion transport
(GO:0006826)
Membrane
(GO:0016020)
Metal ion binding
(GO:0046872)
Mitochondrion
(GO:0005739)
Negative regulation of fibroblast proliferation
(GO:0048147)
Oxidoreductase activity
(GO:0016491)

Other Information

Proteins

Ferritin heavy chain

Genular Protein ID: 254719898

Symbol: FRIH_MOUSE

Name: Ferritin heavy chain

UniProtKB Accession Codes:

P09528 Q3UI44

Database IDs:

Citations:

PubMed ID: 2798146

Title: Nucleotide sequence of the mouse ferritin H chain gene.

PubMed ID: 2798146

DOI: 10.1093/nar/17.19.8005

PubMed ID: 3194211

Title: Nucleotide sequence of cDNA encoding the heavy subunit of mouse macrophage ferritin.

PubMed ID: 3194211

DOI: 10.1093/nar/16.21.10373

PubMed ID: 3410854

Title: The molecular cloning and characterization of murine ferritin heavy chain, a tumor necrosis factor-inducible gene.

PubMed ID: 3410854

DOI: 10.1016/s0021-9258(18)37801-3

PubMed ID: 2258056

Title: Murine ferritin heavy chain: isolation and characterization of a functional gene.

PubMed ID: 2258056

DOI: 10.1016/0378-1119(90)90396-9

PubMed ID: 2708374

Title: Transcriptional regulation of ferritin H and L subunits in adult erythroid and liver cells from the mouse. Unambiguous identification of mouse ferritin subunits and in vitro formation of the ferritin shells.

PubMed ID: 2708374

DOI: 10.1016/s0021-9258(18)83262-8

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 10652280

Title: Early embryonic lethality of H ferritin gene deletion in mice.

PubMed ID: 10652280

DOI: 10.1074/jbc.275.5.3021

PubMed ID: 11468145

Title: H ferritin knockout mice: a model of hyperferritinemia in the absence of iron overload.

PubMed ID: 11468145

DOI: 10.1182/blood.v98.3.525

PubMed ID: 19154717

Title: Scara5 is a ferritin receptor mediating non-transferrin iron delivery.

PubMed ID: 19154717

DOI: 10.1016/j.devcel.2008.12.002

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

Sequence Information:

Length: 182
Mass: 21067
Checksum: 129A8887A2BC650B
Sequence:

MTTASPSQVR QNYHQDAEAA INRQINLELY ASYVYLSMSC YFDRDDVALK NFAKYFLHQS 
HEEREHAEKL MKLQNQRGGR IFLQDIKKPD RDDWESGLNA MECALHLEKS VNQSLLELHK 
LATDKNDPHL CDFIETYYLS EQVKSIKELG DHVTNLRKMG APEAGMAEYL FDKHTLGHGD 
ES

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Fth1

Associated with

Other Information

Nucleotide sequence of the mouse ferritin H chain gene. PubMed ID: 2798146

Nucleotide sequence of cDNA encoding the heavy subunit of mouse macrophage ferritin. PubMed ID: 3194211

The molecular cloning and characterization of murine ferritin heavy chain, a tumor necrosis factor-inducible gene. PubMed ID: 3410854

Murine ferritin heavy chain: isolation and characterization of a functional gene. PubMed ID: 2258056

Transcriptional regulation of ferritin H and L subunits in adult erythroid and liver cells from the mouse. Unambiguous identification of mouse ferritin subunits and in vitro formation of the ferritin shells. PubMed ID: 2708374

The transcriptional landscape of the mammalian genome. PubMed ID: 16141072

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Early embryonic lethality of H ferritin gene deletion in mice. PubMed ID: 10652280

H ferritin knockout mice: a model of hyperferritinemia in the absence of iron overload. PubMed ID: 11468145

Scara5 is a ferritin receptor mediating non-transferrin iron delivery. PubMed ID: 19154717

A tissue-specific atlas of mouse protein phosphorylation and expression. PubMed ID: 21183079