Details for: CSE1L
Associated with
Cells (max top 100)
(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: polychromatophilic erythroblast (CL0000550)
Fold Change: 162.8465
Cell Significance Index: -25.3300 - Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
Fold Change: 120.9967
Cell Significance Index: -30.6900 - Cell Name: embryonic stem cell (CL0002322)
Fold Change: 75.6407
Cell Significance Index: -31.1600 - Cell Name: smooth muscle fiber of ileum (CL1000278)
Fold Change: 73.3072
Cell Significance Index: -34.6100 - Cell Name: mucosal type mast cell (CL0000485)
Fold Change: 69.3526
Cell Significance Index: -28.1800 - Cell Name: ciliated cell of the bronchus (CL0002332)
Fold Change: 29.7200
Cell Significance Index: -28.3800 - Cell Name: orthochromatic erythroblast (CL0000552)
Fold Change: 26.1485
Cell Significance Index: -32.2400 - Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
Fold Change: 11.9902
Cell Significance Index: -32.1200 - Cell Name: stromal cell of bone marrow (CL0010001)
Fold Change: 8.3704
Cell Significance Index: -33.0300 - Cell Name: epidermal Langerhans cell (CL0002457)
Fold Change: 5.0763
Cell Significance Index: -11.1100 - Cell Name: enteroendocrine cell of colon (CL0009042)
Fold Change: 2.8865
Cell Significance Index: 549.3200 - Cell Name: placental villous trophoblast (CL2000060)
Fold Change: 2.0182
Cell Significance Index: 53.8900 - Cell Name: epithelial cell of small intestine (CL0002254)
Fold Change: 1.9565
Cell Significance Index: 318.2100 - Cell Name: neoplastic cell (CL0001063)
Fold Change: 1.9074
Cell Significance Index: 378.5300 - Cell Name: germ cell (CL0000586)
Fold Change: 1.7608
Cell Significance Index: 13.3000 - Cell Name: decidual cell (CL2000002)
Fold Change: 1.7019
Cell Significance Index: 27.3100 - Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
Fold Change: 1.2850
Cell Significance Index: 35.9100 - Cell Name: tuft cell of colon (CL0009041)
Fold Change: 1.1122
Cell Significance Index: 1004.2300 - Cell Name: gut absorptive cell (CL0000677)
Fold Change: 0.9751
Cell Significance Index: 58.5400 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: 0.9627
Cell Significance Index: 193.1100 - Cell Name: conjunctival epithelial cell (CL1000432)
Fold Change: 0.8854
Cell Significance Index: 12.0800 - Cell Name: retinal progenitor cell (CL0002672)
Fold Change: 0.8590
Cell Significance Index: 48.2100 - Cell Name: basal cell of urothelium (CL1000486)
Fold Change: 0.5271
Cell Significance Index: 64.8200 - Cell Name: intermediate cell of urothelium (CL4030055)
Fold Change: 0.5235
Cell Significance Index: 94.3700 - Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: 0.4900
Cell Significance Index: 175.7700 - Cell Name: cell in vitro (CL0001034)
Fold Change: 0.4568
Cell Significance Index: 249.4700 - Cell Name: microfold cell of epithelium of small intestine (CL1000353)
Fold Change: 0.4295
Cell Significance Index: 29.7100 - Cell Name: basal cell of prostate epithelium (CL0002341)
Fold Change: 0.4170
Cell Significance Index: 11.3500 - Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
Fold Change: 0.3540
Cell Significance Index: 12.3000 - Cell Name: forebrain neuroblast (CL1000042)
Fold Change: 0.3513
Cell Significance Index: 21.5900 - Cell Name: bladder urothelial cell (CL1001428)
Fold Change: 0.3444
Cell Significance Index: 17.8900 - Cell Name: GABAergic interneuron (CL0011005)
Fold Change: 0.3270
Cell Significance Index: 226.1900 - Cell Name: hair follicular keratinocyte (CL2000092)
Fold Change: 0.3018
Cell Significance Index: 133.4500 - Cell Name: stromal cell of ovary (CL0002132)
Fold Change: 0.2822
Cell Significance Index: 38.7600 - Cell Name: lung endothelial cell (CL1001567)
Fold Change: 0.2766
Cell Significance Index: 14.4100 - Cell Name: tonsil germinal center B cell (CL2000006)
Fold Change: 0.2415
Cell Significance Index: 28.4800 - Cell Name: enteroendocrine cell of small intestine (CL0009006)
Fold Change: 0.2316
Cell Significance Index: 5.7900 - Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
Fold Change: 0.2016
Cell Significance Index: 9.4800 - Cell Name: cortical cell of adrenal gland (CL0002097)
Fold Change: 0.1980
Cell Significance Index: 5.3100 - Cell Name: sebum secreting cell (CL0000317)
Fold Change: 0.1953
Cell Significance Index: 13.8100 - Cell Name: skeletal muscle myoblast (CL0000515)
Fold Change: 0.1886
Cell Significance Index: 2.0500 - Cell Name: acinar cell of salivary gland (CL0002623)
Fold Change: 0.1682
Cell Significance Index: 7.8400 - Cell Name: odontoblast (CL0000060)
Fold Change: 0.1436
Cell Significance Index: 18.4100 - Cell Name: pancreatic acinar cell (CL0002064)
Fold Change: 0.1431
Cell Significance Index: 24.4300 - Cell Name: colon goblet cell (CL0009039)
Fold Change: 0.1381
Cell Significance Index: 13.6600 - Cell Name: paneth cell of epithelium of small intestine (CL1000343)
Fold Change: 0.1274
Cell Significance Index: 2.7600 - Cell Name: lactocyte (CL0002325)
Fold Change: 0.0952
Cell Significance Index: 12.3100 - Cell Name: transit amplifying cell of colon (CL0009011)
Fold Change: 0.0774
Cell Significance Index: 2.4800 - Cell Name: enterocyte of epithelium of large intestine (CL0002071)
Fold Change: 0.0715
Cell Significance Index: 3.2400 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: 0.0693
Cell Significance Index: 5.3200 - Cell Name: secondary lens fiber (CL0002225)
Fold Change: 0.0682
Cell Significance Index: 92.7900 - Cell Name: lens epithelial cell (CL0002224)
Fold Change: 0.0634
Cell Significance Index: 97.5400 - Cell Name: enterocyte of epithelium of small intestine (CL1000334)
Fold Change: 0.0521
Cell Significance Index: 1.5000 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: 0.0506
Cell Significance Index: 95.2200 - Cell Name: anterior lens cell (CL0002223)
Fold Change: 0.0376
Cell Significance Index: 69.2600 - Cell Name: cerebellar granule cell (CL0001031)
Fold Change: 0.0152
Cell Significance Index: 0.2600 - Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: 0.0107
Cell Significance Index: 6.8200 - Cell Name: ciliary muscle cell (CL1000443)
Fold Change: -0.0087
Cell Significance Index: -3.9500 - Cell Name: pancreatic A cell (CL0000171)
Fold Change: -0.0102
Cell Significance Index: -7.5400 - Cell Name: pancreatic PP cell (CL0002275)
Fold Change: -0.0112
Cell Significance Index: -7.0200 - Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
Fold Change: -0.0179
Cell Significance Index: -13.1400 - Cell Name: eye photoreceptor cell (CL0000287)
Fold Change: -0.0217
Cell Significance Index: -1.3700 - Cell Name: skeletal muscle fiber (CL0008002)
Fold Change: -0.0253
Cell Significance Index: -0.6500 - Cell Name: pulmonary alveolar epithelial cell (CL0000322)
Fold Change: -0.0257
Cell Significance Index: -19.4400 - Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
Fold Change: -0.0263
Cell Significance Index: -0.5600 - Cell Name: small intestine goblet cell (CL1000495)
Fold Change: -0.0265
Cell Significance Index: -0.9300 - Cell Name: type B pancreatic cell (CL0000169)
Fold Change: -0.0351
Cell Significance Index: -19.8000 - Cell Name: pigmented ciliary epithelial cell (CL0002303)
Fold Change: -0.0373
Cell Significance Index: -5.4200 - Cell Name: granulosa cell (CL0000501)
Fold Change: -0.0612
Cell Significance Index: -1.6100 - Cell Name: mesenchymal cell (CL0008019)
Fold Change: -0.0729
Cell Significance Index: -1.2200 - Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
Fold Change: -0.0754
Cell Significance Index: -5.6200 - Cell Name: abnormal cell (CL0001061)
Fold Change: -0.0758
Cell Significance Index: -7.7400 - Cell Name: pancreatic D cell (CL0000173)
Fold Change: -0.0814
Cell Significance Index: -17.1600 - Cell Name: Purkinje cell (CL0000121)
Fold Change: -0.0872
Cell Significance Index: -1.9100 - Cell Name: hippocampal granule cell (CL0001033)
Fold Change: -0.0889
Cell Significance Index: -5.9800 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: -0.0952
Cell Significance Index: -27.4000 - Cell Name: epithelial cell of stomach (CL0002178)
Fold Change: -0.1093
Cell Significance Index: -12.7400 - Cell Name: leptomeningeal cell (CL0000708)
Fold Change: -0.1109
Cell Significance Index: -2.3700 - Cell Name: early pro-B cell (CL0002046)
Fold Change: -0.1314
Cell Significance Index: -8.4800 - Cell Name: indirect pathway medium spiny neuron (CL4023029)
Fold Change: -0.1316
Cell Significance Index: -5.8200 - Cell Name: cortical interneuron (CL0008031)
Fold Change: -0.1347
Cell Significance Index: -3.2300 - Cell Name: endothelial cell of placenta (CL0009092)
Fold Change: -0.1473
Cell Significance Index: -0.8900 - Cell Name: fibroblast of dermis (CL0002551)
Fold Change: -0.1634
Cell Significance Index: -3.4200 - Cell Name: pancreatic ductal cell (CL0002079)
Fold Change: -0.1804
Cell Significance Index: -20.6700 - Cell Name: pancreatic endocrine cell (CL0008024)
Fold Change: -0.2021
Cell Significance Index: -23.0700 - Cell Name: direct pathway medium spiny neuron (CL4023026)
Fold Change: -0.2044
Cell Significance Index: -7.7400 - Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
Fold Change: -0.2791
Cell Significance Index: -29.0600 - Cell Name: glycinergic neuron (CL1001509)
Fold Change: -0.2988
Cell Significance Index: -15.6900 - Cell Name: pro-T cell (CL0000827)
Fold Change: -0.3347
Cell Significance Index: -8.5500 - Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
Fold Change: -0.3370
Cell Significance Index: -26.6900 - Cell Name: intestinal tuft cell (CL0019032)
Fold Change: -0.3446
Cell Significance Index: -21.1300 - Cell Name: preadipocyte (CL0002334)
Fold Change: -0.3535
Cell Significance Index: -6.9000 - Cell Name: fibroblast of mammary gland (CL0002555)
Fold Change: -0.3907
Cell Significance Index: -11.2000 - Cell Name: Hofbauer cell (CL3000001)
Fold Change: -0.4059
Cell Significance Index: -3.3100 - Cell Name: retinal rod cell (CL0000604)
Fold Change: -0.4530
Cell Significance Index: -5.4000 - Cell Name: hippocampal pyramidal neuron (CL1001571)
Fold Change: -0.4899
Cell Significance Index: -13.9800 - Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
Fold Change: -0.5715
Cell Significance Index: -12.1300 - Cell Name: L6b glutamatergic cortical neuron (CL4023038)
Fold Change: -0.5799
Cell Significance Index: -18.9900 - Cell Name: peg cell (CL4033014)
Fold Change: -0.5986
Cell Significance Index: -13.8300 - Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
Fold Change: -0.6236
Cell Significance Index: -19.8600
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 836484772
Symbol: XPO2_HUMAN
Name: Exportin-2
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 7479798
Title: Cloning and characterization of a cellular apoptosis susceptibility gene, the human homologue to the yeast chromosome segregation gene CSE1.
PubMed ID: 7479798
PubMed ID: 10331944
Title: Tissue-specific alternative splicing of the CSE1L/CAS (cellular apoptosis susceptibility) gene.
PubMed ID: 10331944
PubMed ID: 11703094
Title: IRF-1-mediated CAS expression enhances interferon-gamma-induced apoptosis of HT-29 colon adenocarcinoma cells.
PubMed ID: 11703094
PubMed ID: 14702039
Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.
PubMed ID: 14702039
DOI: 10.1038/ng1285
PubMed ID: 11780052
Title: The DNA sequence and comparative analysis of human chromosome 20.
PubMed ID: 11780052
DOI: 10.1038/414865a
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 9323134
Title: Export of importin-alpha from the nucleus is mediated by a specific nuclear transport factor.
PubMed ID: 9323134
PubMed ID: 9786944
Title: Determination of the functional domain organization of the importin alpha nuclear import factor.
PubMed ID: 9786944
PubMed ID: 14654843
Title: Proteomic characterization of the human centrosome by protein correlation profiling.
PubMed ID: 14654843
DOI: 10.1038/nature02166
PubMed ID: 19413330
Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.
PubMed ID: 19413330
DOI: 10.1021/ac9004309
PubMed ID: 19608861
Title: Lysine acetylation targets protein complexes and co-regulates major cellular functions.
PubMed ID: 19608861
PubMed ID: 20933420
Title: Cse1l is a negative regulator of CFTR-dependent fluid secretion.
PubMed ID: 20933420
PubMed ID: 21269460
Title: Initial characterization of the human central proteome.
PubMed ID: 21269460
PubMed ID: 22223895
Title: Comparative large-scale characterisation of plant vs. mammal proteins reveals similar and idiosyncratic N-alpha acetylation features.
PubMed ID: 22223895
PubMed ID: 22814378
Title: N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.
PubMed ID: 22814378
PubMed ID: 23186163
Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.
PubMed ID: 23186163
DOI: 10.1021/pr300630k
PubMed ID: 24275569
Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.
PubMed ID: 24275569
PubMed ID: 25944712
Title: N-terminome analysis of the human mitochondrial proteome.
PubMed ID: 25944712
PubMed ID: 16959974
Title: The consensus coding sequences of human breast and colorectal cancers.
PubMed ID: 16959974
Sequence Information:
- Length: 971
- Mass: 110417
- Checksum: 08E837AB5008EBFD
- Sequence:
MELSDANLQT LTEYLKKTLD PDPAIRRPAE KFLESVEGNQ NYPLLLLTLL EKSQDNVIKV CASVTFKNYI KRNWRIVEDE PNKICEADRV AIKANIVHLM LSSPEQIQKQ LSDAISIIGR EDFPQKWPDL LTEMVNRFQS GDFHVINGVL RTAHSLFKRY RHEFKSNELW TEIKLVLDAF ALPLTNLFKA TIELCSTHAN DASALRILFS SLILISKLFY SLNFQDLPEF FEDNMETWMN NFHTLLTLDN KLLQTDDEEE AGLLELLKSQ ICDNAALYAQ KYDEEFQRYL PRFVTAIWNL LVTTGQEVKY DLLVSNAIQF LASVCERPHY KNLFEDQNTL TSICEKVIVP NMEFRAADEE AFEDNSEEYI RRDLEGSDID TRRRAACDLV RGLCKFFEGP VTGIFSGYVN SMLQEYAKNP SVNWKHKDAA IYLVTSLASK AQTQKHGITQ ANELVNLTEF FVNHILPDLK SANVNEFPVL KADGIKYIMI FRNQVPKEHL LVSIPLLINH LQAESIVVHT YAAHALERLF TMRGPNNATL FTAAEIAPFV EILLTNLFKA LTLPGSSENE YIMKAIMRSF SLLQEAIIPY IPTLITQLTQ KLLAVSKNPS KPHFNHYMFE AICLSIRITC KANPAAVVNF EEALFLVFTE ILQNDVQEFI PYVFQVMSLL LETHKNDIPS SYMALFPHLL QPVLWERTGN IPALVRLLQA FLERGSNTIA SAAADKIPGL LGVFQKLIAS KANDHQGFYL LNSIIEHMPP ESVDQYRKQI FILLFQRLQN SKTTKFIKSF LVFINLYCIK YGALALQEIF DGIQPKMFGM VLEKIIIPEI QKVSGNVEKK ICAVGITKLL TECPPMMDTE YTKLWTPLLQ SLIGLFELPE DDTIPDEEHF IDIEDTPGYQ TAFSQLAFAG KKEHDPVGQM VNNPKIHLAQ SLHKLSTACP GRVPSMVSTS LNAEALQYLQ GYLQAASVTL L
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.