Details for: CSF1
Associated with
Cells (max top 100)
(Marker Score score is uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: fibroblast of mammary gland (CL0002555)
Fold Change: 1.65
Marker Score: 56159 - Cell Name: alveolar capillary type 2 endothelial cell (CL4028003)
Fold Change: 1.57
Marker Score: 2275 - Cell Name: basophil (CL0000767)
Fold Change: 1.47
Marker Score: 699 - Cell Name: decidual natural killer cell, human (CL0002343)
Fold Change: 1.37
Marker Score: 3789 - Cell Name: enterocyte of epithelium of large intestine (CL0002071)
Fold Change: 1.32
Marker Score: 1319 - Cell Name: immature innate lymphoid cell (CL0001082)
Fold Change: 1.28
Marker Score: 2601 - Cell Name: fibroblast of connective tissue of nonglandular part of prostate (CL1000304)
Fold Change: 1.18
Marker Score: 1005 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: 1.11
Marker Score: 17396 - Cell Name: colon goblet cell (CL0009039)
Fold Change: 1.09
Marker Score: 794 - Cell Name: fibroblast of connective tissue of glandular part of prostate (CL1000305)
Fold Change: 1.09
Marker Score: 453 - Cell Name: skeletal muscle satellite stem cell (CL0008011)
Fold Change: 1.08
Marker Score: 1149 - Cell Name: vascular leptomeningeal cell (CL4023051)
Fold Change: 1.07
Marker Score: 1229 - Cell Name: fallopian tube secretory epithelial cell (CL4030006)
Fold Change: 1.04
Marker Score: 251761 - Cell Name: eurydendroid cell (CL0000253)
Fold Change: 1.03
Marker Score: 421 - Cell Name: adventitial cell (CL0002503)
Fold Change: 1.02
Marker Score: 251 - Cell Name: cerebral cortex GABAergic interneuron (CL0010011)
Fold Change: 1
Marker Score: 71779 - Cell Name: forebrain radial glial cell (CL0013000)
Fold Change: 1
Marker Score: 48004 - Cell Name: keratocyte (CL0002363)
Fold Change: 0.99
Marker Score: 228 - Cell Name: absorptive cell (CL0000212)
Fold Change: 0.98
Marker Score: 30404 - Cell Name: myoepithelial cell of mammary gland (CL0002324)
Fold Change: 0.98
Marker Score: 4802 - Cell Name: fibroblast of cardiac tissue (CL0002548)
Fold Change: 0.97
Marker Score: 5800 - Cell Name: tuft cell of colon (CL0009041)
Fold Change: 0.95
Marker Score: 490 - Cell Name: choroid plexus epithelial cell (CL0000706)
Fold Change: 0.95
Marker Score: 871 - Cell Name: intestinal crypt stem cell of colon (CL0009043)
Fold Change: 0.95
Marker Score: 2409 - Cell Name: BEST4+ intestinal epithelial cell, human (CL4030026)
Fold Change: 0.94
Marker Score: 443 - Cell Name: transit amplifying cell (CL0009010)
Fold Change: 0.92
Marker Score: 5246 - Cell Name: cortical thymic epithelial cell (CL0002364)
Fold Change: 0.92
Marker Score: 3397 - Cell Name: abnormal cell (CL0001061)
Fold Change: 0.91
Marker Score: 2726 - Cell Name: small intestine goblet cell (CL1000495)
Fold Change: 0.89
Marker Score: 358 - Cell Name: smooth muscle myoblast (CL0000514)
Fold Change: 0.87
Marker Score: 416 - Cell Name: neoplastic cell (CL0001063)
Fold Change: 0.87
Marker Score: 5267 - Cell Name: epithelial cell of small intestine (CL0002254)
Fold Change: 0.87
Marker Score: 312 - Cell Name: pancreatic ductal cell (CL0002079)
Fold Change: 0.85
Marker Score: 882 - Cell Name: lymphoid lineage restricted progenitor cell (CL0000838)
Fold Change: 0.85
Marker Score: 509 - Cell Name: astrocyte of the cerebral cortex (CL0002605)
Fold Change: 0.83
Marker Score: 17757 - Cell Name: fibroblast of lung (CL0002553)
Fold Change: 0.82
Marker Score: 2143 - Cell Name: kidney proximal straight tubule epithelial cell (CL1000839)
Fold Change: 0.79
Marker Score: 1862 - Cell Name: alveolar capillary type 1 endothelial cell (CL4028002)
Fold Change: 0.78
Marker Score: 1981 - Cell Name: intestinal epithelial cell (CL0002563)
Fold Change: 0.76
Marker Score: 1239 - Cell Name: fibroblast of connective tissue of prostate (CL1000299)
Fold Change: 0.75
Marker Score: 187 - Cell Name: early T lineage precursor (CL0002425)
Fold Change: 0.75
Marker Score: 569.5 - Cell Name: prostate stromal cell (CL0002622)
Fold Change: 0.74
Marker Score: 187 - Cell Name: preosteoblast (CL0007010)
Fold Change: 0.74
Marker Score: 210 - Cell Name: kidney capillary endothelial cell (CL1000892)
Fold Change: 0.73
Marker Score: 230 - Cell Name: Cajal-Retzius cell (CL0000695)
Fold Change: 0.73
Marker Score: 379 - Cell Name: neuroendocrine cell (CL0000165)
Fold Change: 0.72
Marker Score: 280 - Cell Name: brush cell (CL0002204)
Fold Change: 0.71
Marker Score: 650 - Cell Name: enterocyte of epithelium of small intestine (CL1000334)
Fold Change: 0.71
Marker Score: 2970 - Cell Name: B-2 B cell (CL0000822)
Fold Change: 0.69
Marker Score: 846 - Cell Name: mesenchymal lymphangioblast (CL0005021)
Fold Change: 0.67
Marker Score: 150 - Cell Name: inflammatory cell (CL0009002)
Fold Change: 0.67
Marker Score: 288 - Cell Name: neutrophil progenitor cell (CL0000834)
Fold Change: 0.67
Marker Score: 171 - Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
Fold Change: 0.63
Marker Score: 4045 - Cell Name: fibroblast (CL0000057)
Fold Change: 0.62
Marker Score: 599 - Cell Name: lung endothelial cell (CL1001567)
Fold Change: 0.6
Marker Score: 5295 - Cell Name: medullary thymic epithelial cell (CL0002365)
Fold Change: 0.59
Marker Score: 969 - Cell Name: skeletal muscle fibroblast (CL0011027)
Fold Change: 0.58
Marker Score: 383 - Cell Name: retinal blood vessel endothelial cell (CL0002585)
Fold Change: 0.58
Marker Score: 139 - Cell Name: neuronal receptor cell (CL0000006)
Fold Change: 0.57
Marker Score: 252 - Cell Name: hematopoietic cell (CL0000988)
Fold Change: 0.56
Marker Score: 372 - Cell Name: transit amplifying cell of small intestine (CL0009012)
Fold Change: 0.56
Marker Score: 231 - Cell Name: intestinal enteroendocrine cell (CL1001516)
Fold Change: 0.55
Marker Score: 435 - Cell Name: mast cell (CL0000097)
Fold Change: 0.54
Marker Score: 314 - Cell Name: alveolar macrophage (CL0000583)
Fold Change: 0.54
Marker Score: 13840 - Cell Name: leptomeningeal cell (CL0000708)
Fold Change: 0.54
Marker Score: 266 - Cell Name: common myeloid progenitor (CL0000049)
Fold Change: 0.53
Marker Score: 140 - Cell Name: myofibroblast cell (CL0000186)
Fold Change: 0.53
Marker Score: 649 - Cell Name: stromal cell (CL0000499)
Fold Change: 0.52
Marker Score: 611 - Cell Name: stromal cell of lamina propria of small intestine (CL0009022)
Fold Change: 0.52
Marker Score: 117 - Cell Name: endothelial cell of vascular tree (CL0002139)
Fold Change: 0.51
Marker Score: 748 - Cell Name: astrocyte (CL0000127)
Fold Change: 0.49
Marker Score: 428 - Cell Name: granulocyte (CL0000094)
Fold Change: 0.49
Marker Score: 221 - Cell Name: renal interstitial pericyte (CL1001318)
Fold Change: 0.49
Marker Score: 469 - Cell Name: mucus secreting cell (CL0000319)
Fold Change: 0.48
Marker Score: 123 - Cell Name: vascular associated smooth muscle cell (CL0000359)
Fold Change: 0.47
Marker Score: 217 - Cell Name: subcutaneous fat cell (CL0002521)
Fold Change: 0.47
Marker Score: 171 - Cell Name: reticular cell (CL0000432)
Fold Change: 0.45
Marker Score: 166 - Cell Name: kidney interstitial fibroblast (CL1000692)
Fold Change: 0.45
Marker Score: 874 - Cell Name: pulmonary artery endothelial cell (CL1001568)
Fold Change: 0.45
Marker Score: 389 - Cell Name: bronchus fibroblast of lung (CL2000093)
Fold Change: 0.45
Marker Score: 615 - Cell Name: endothelial cell of hepatic sinusoid (CL1000398)
Fold Change: 0.44
Marker Score: 97 - Cell Name: endothelial cell (CL0000115)
Fold Change: 0.44
Marker Score: 393 - Cell Name: fat cell (CL0000136)
Fold Change: 0.44
Marker Score: 245 - Cell Name: granulocyte monocyte progenitor cell (CL0000557)
Fold Change: 0.44
Marker Score: 278 - Cell Name: osteoblast (CL0000062)
Fold Change: 0.44
Marker Score: 235 - Cell Name: mature astrocyte (CL0002627)
Fold Change: 0.43
Marker Score: 286 - Cell Name: exhausted T cell (CL0011025)
Fold Change: 0.43
Marker Score: 249 - Cell Name: type B pancreatic cell (CL0000169)
Fold Change: 0.43
Marker Score: 426 - Cell Name: mammary gland epithelial cell (CL0002327)
Fold Change: 0.42
Marker Score: 151 - Cell Name: peritubular capillary endothelial cell (CL1001033)
Fold Change: 0.42
Marker Score: 98 - Cell Name: vascular lymphangioblast (CL0005022)
Fold Change: 0.42
Marker Score: 711 - Cell Name: mesothelial cell of epicardium (CL0011019)
Fold Change: 0.42
Marker Score: 134 - Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
Fold Change: 0.42
Marker Score: 282 - Cell Name: pericyte (CL0000669)
Fold Change: 0.42
Marker Score: 243 - Cell Name: supporting cell (CL0000630)
Fold Change: 0.41
Marker Score: 779 - Cell Name: pancreatic stellate cell (CL0002410)
Fold Change: 0.41
Marker Score: 260.5 - Cell Name: epicardial adipocyte (CL1000309)
Fold Change: 0.41
Marker Score: 199 - Cell Name: glandular epithelial cell (CL0000150)
Fold Change: 0.41
Marker Score: 1006 - Cell Name: erythroid progenitor cell, mammalian (CL0001066)
Fold Change: 0.4
Marker Score: 129 - Cell Name: primitive red blood cell (CL0002355)
Fold Change: 0.4
Marker Score: 301
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Other Information
Genular Protein ID: 358682337
Symbol: CSF1_HUMAN
Name: Macrophage colony-stimulating factor 1
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 2996129
Title: Molecular cloning of a complementary DNA encoding human macrophage-specific colony-stimulating factor (CSF-1).
PubMed ID: 2996129
PubMed ID: 3493529
Title: Human CSF-1: molecular cloning and expression of 4-kb cDNA encoding the human urinary protein.
PubMed ID: 3493529
PubMed ID: 2460758
Title: Human macrophage-colony stimulating factor: alternative RNA and protein processing from a single gene.
PubMed ID: 2460758
PubMed ID: 2660794
Title: Amino-terminal region of human macrophage colony-stimulating factor (M-CSF) is sufficient for its in vitro biological activity: molecular cloning and expression of carboxyl-terminal deletion mutants of human M-CSF.
PubMed ID: 2660794
PubMed ID: 14702039
Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.
PubMed ID: 14702039
DOI: 10.1038/ng1285
PubMed ID: 16710414
Title: The DNA sequence and biological annotation of human chromosome 1.
PubMed ID: 16710414
DOI: 10.1038/nature04727
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 3500041
Title: Human CSF-1: gene structure and alternative splicing of mRNA precursors.
PubMed ID: 3500041
PubMed ID: 1791839
Title: Expression of colony-stimulating factor-1 (CSF-1) messenger RNA in human endometrial glands during the menstrual cycle: molecular cloning of a novel transcript that predicts a cell surface form of CSF-1.
PubMed ID: 1791839
PubMed ID: 8262907
Title: The structure of recombinant human carboxy-terminal-truncated macrophage colony-stimulating factor derived from mammalian cells.
PubMed ID: 8262907
PubMed ID: 3498652
Title: Macrophage colony-stimulating factor purified from normal human urine. Amino-terminal sequence and amino acid composition.
PubMed ID: 3498652
PubMed ID: 8051056
Title: Structural analysis of proteoglycan macrophage colony-stimulating factor.
PubMed ID: 8051056
PubMed ID: 3259875
Title: Macrophage colony-stimulating factor is produced by human T lymphoblastoid cell line, CEM-ON: identification by amino-terminal amino acid sequence analysis.
PubMed ID: 3259875
PubMed ID: 3039346
Title: Synthesis of membrane-bound colony-stimulating factor 1 (CSF-1) and downmodulation of CSF-1 receptors in NIH 3T3 cells transformed by cotransfection of the human CSF-1 and c-fms (CSF-1 receptor) genes.
PubMed ID: 3039346
PubMed ID: 3264877
Title: Differential processing of colony-stimulating factor 1 precursors encoded by two human cDNAs.
PubMed ID: 3264877
PubMed ID: 1531650
Title: Identification of a high molecular weight macrophage colony-stimulating factor as a glycosaminoglycan-containing species.
PubMed ID: 1531650
PubMed ID: 8422357
Title: Assignment of the inter- and intramolecular disulfide linkages in recombinant human macrophage colony stimulating factor using fast atom bombardment mass spectrometry.
PubMed ID: 8422357
DOI: 10.1021/bi00053a012
PubMed ID: 15519852
Title: CSF-1 regulation of the wandering macrophage: complexity in action.
PubMed ID: 15519852
PubMed ID: 16337366
Title: Colony-stimulating factor-1 in immunity and inflammation.
PubMed ID: 16337366
PubMed ID: 18687298
Title: Macrophage colony stimulating factor: not just for macrophages anymore! A gateway into complex biologies.
PubMed ID: 18687298
PubMed ID: 19934330
Title: Invasion of human breast cancer cells in vivo requires both paracrine and autocrine loops involving the colony-stimulating factor-1 receptor.
PubMed ID: 19934330
PubMed ID: 20829061
Title: Macrophage-colony stimulating factor and interleukin-34 induce chemokines in human whole blood.
PubMed ID: 20829061
PubMed ID: 20504948
Title: Functional overlap but differential expression of CSF-1 and IL-34 in their CSF-1 receptor-mediated regulation of myeloid cells.
PubMed ID: 20504948
DOI: 10.1189/jlb.1209822
PubMed ID: 22171320
Title: Human urinary glycoproteomics; attachment site specific analysis of N- and O-linked glycosylations by CID and ECD.
PubMed ID: 22171320
PubMed ID: 23186163
Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.
PubMed ID: 23186163
DOI: 10.1021/pr300630k
PubMed ID: 23234360
Title: LC-MS/MS characterization of O-glycosylation sites and glycan structures of human cerebrospinal fluid glycoproteins.
PubMed ID: 23234360
DOI: 10.1021/pr300963h
PubMed ID: 26091039
Title: A single kinase generates the majority of the secreted phosphoproteome.
PubMed ID: 26091039
PubMed ID: 1455231
Title: Three-dimensional structure of dimeric human recombinant macrophage colony-stimulating factor.
PubMed ID: 1455231
Sequence Information:
- Length: 554
- Mass: 60179
- Checksum: 656B0894F9255AED
- Sequence:
MTAPGAAGRC PPTTWLGSLL LLVCLLASRS ITEEVSEYCS HMIGSGHLQS LQRLIDSQME TSCQITFEFV DQEQLKDPVC YLKKAFLLVQ DIMEDTMRFR DNTPNAIAIV QLQELSLRLK SCFTKDYEEH DKACVRTFYE TPLQLLEKVK NVFNETKNLL DKDWNIFSKN CNNSFAECSS QDVVTKPDCN CLYPKAIPSS DPASVSPHQP LAPSMAPVAG LTWEDSEGTE GSSLLPGEQP LHTVDPGSAK QRPPRSTCQS FEPPETPVVK DSTIGGSPQP RPSVGAFNPG MEDILDSAMG TNWVPEEASG EASEIPVPQG TELSPSRPGG GSMQTEPARP SNFLSASSPL PASAKGQQPA DVTGTALPRV GPVRPTGQDW NHTPQKTDHP SALLRDPPEP GSPRISSLRP QGLSNPSTLS AQPQLSRSHS SGSVLPLGEL EGRRSTRDRR SPAEPEGGPA SEGAARPLPR FNSVPLTDTG HERQSEGSFS PQLQESVFHL LVPSVILVLL AVGGLLFYRW RRRSHQEPQR ADSPLEQPEG SPLTQDDRQV ELPV
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. For the full schema, download it here.