Details for: CSF1

Gene ID: 1435

Symbol: CSF1

Ensembl ID: ENSG00000184371

Description: colony stimulating factor 1

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 91.4846
    Cell Significance Index: -14.2300
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 58.9804
    Cell Significance Index: -14.9600
  • Cell Name: smooth muscle fiber of ileum (CL1000278)
    Fold Change: 30.5959
    Cell Significance Index: -14.4500
  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 30.1533
    Cell Significance Index: -12.2500
  • Cell Name: ciliated cell of the bronchus (CL0002332)
    Fold Change: 13.0821
    Cell Significance Index: -12.4900
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 11.9226
    Cell Significance Index: -14.7000
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 5.6685
    Cell Significance Index: -15.1900
  • Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
    Fold Change: 4.1804
    Cell Significance Index: -12.8400
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 3.6467
    Cell Significance Index: -14.3900
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: 2.8097
    Cell Significance Index: 89.9900
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: 2.2536
    Cell Significance Index: 64.6000
  • Cell Name: microcirculation associated smooth muscle cell (CL0008035)
    Fold Change: 2.0762
    Cell Significance Index: 17.4400
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 1.6077
    Cell Significance Index: 72.8700
  • Cell Name: proerythroblast (CL0000547)
    Fold Change: 1.1727
    Cell Significance Index: 16.8100
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.8469
    Cell Significance Index: 83.7800
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.7333
    Cell Significance Index: 662.1600
  • Cell Name: preadipocyte (CL0002334)
    Fold Change: 0.6840
    Cell Significance Index: 13.3500
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: 0.6209
    Cell Significance Index: 32.3400
  • Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
    Fold Change: 0.5897
    Cell Significance Index: 17.3200
  • Cell Name: keratocyte (CL0002363)
    Fold Change: 0.5572
    Cell Significance Index: 8.8400
  • Cell Name: fibro/adipogenic progenitor cell (CL0009099)
    Fold Change: 0.5259
    Cell Significance Index: 26.5800
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.4506
    Cell Significance Index: 73.2800
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 0.3837
    Cell Significance Index: 41.7400
  • Cell Name: pancreatic endocrine cell (CL0008024)
    Fold Change: 0.2723
    Cell Significance Index: 31.0800
  • Cell Name: fallopian tube secretory epithelial cell (CL4030006)
    Fold Change: 0.2553
    Cell Significance Index: 3.9500
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.2522
    Cell Significance Index: 47.9900
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 0.1968
    Cell Significance Index: 13.6100
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: 0.1923
    Cell Significance Index: 9.0400
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.1885
    Cell Significance Index: 37.4200
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: 0.1797
    Cell Significance Index: 10.7900
  • Cell Name: vascular lymphangioblast (CL0005022)
    Fold Change: 0.1590
    Cell Significance Index: 2.8100
  • Cell Name: decidual cell (CL2000002)
    Fold Change: 0.1396
    Cell Significance Index: 2.2400
  • Cell Name: skeletal muscle satellite stem cell (CL0008011)
    Fold Change: 0.1183
    Cell Significance Index: 1.2400
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 0.1065
    Cell Significance Index: 58.1400
  • Cell Name: odontoblast (CL0000060)
    Fold Change: 0.1053
    Cell Significance Index: 13.5000
  • Cell Name: skeletal muscle fibroblast (CL0011027)
    Fold Change: 0.0952
    Cell Significance Index: 0.6500
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 0.0890
    Cell Significance Index: 39.3300
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 0.0679
    Cell Significance Index: 9.3300
  • Cell Name: lactocyte (CL0002325)
    Fold Change: 0.0376
    Cell Significance Index: 4.8600
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.0337
    Cell Significance Index: 0.9700
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: 0.0103
    Cell Significance Index: 0.7300
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: 0.0084
    Cell Significance Index: 0.2100
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: 0.0032
    Cell Significance Index: 0.5400
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: 0.0026
    Cell Significance Index: 1.6400
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: 0.0023
    Cell Significance Index: 0.0500
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: -0.0010
    Cell Significance Index: -1.8700
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.0052
    Cell Significance Index: -0.6000
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: -0.0057
    Cell Significance Index: -0.2000
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: -0.0072
    Cell Significance Index: -0.1200
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0072
    Cell Significance Index: -4.4800
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0096
    Cell Significance Index: -7.2500
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0109
    Cell Significance Index: -8.0900
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: -0.0111
    Cell Significance Index: -20.5000
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: -0.0132
    Cell Significance Index: -20.2800
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0150
    Cell Significance Index: -8.4500
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: -0.0153
    Cell Significance Index: -5.5000
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: -0.0154
    Cell Significance Index: -20.9300
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0182
    Cell Significance Index: -13.3200
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0294
    Cell Significance Index: -13.3300
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: -0.0300
    Cell Significance Index: -5.4000
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: -0.0320
    Cell Significance Index: -3.9400
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.0349
    Cell Significance Index: -10.0400
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.0397
    Cell Significance Index: -8.3600
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.0516
    Cell Significance Index: -6.0100
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: -0.0564
    Cell Significance Index: -11.3100
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.0611
    Cell Significance Index: -8.8800
  • Cell Name: perivascular cell (CL4033054)
    Fold Change: -0.0693
    Cell Significance Index: -0.3200
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.0720
    Cell Significance Index: -7.3500
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: -0.0753
    Cell Significance Index: -2.0500
  • Cell Name: endothelial cell of placenta (CL0009092)
    Fold Change: -0.0977
    Cell Significance Index: -0.5900
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: -0.1102
    Cell Significance Index: -8.2100
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: -0.1110
    Cell Significance Index: -8.5200
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: -0.1160
    Cell Significance Index: -2.4700
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: -0.1170
    Cell Significance Index: -6.0800
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: -0.1180
    Cell Significance Index: -5.5000
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: -0.1333
    Cell Significance Index: -15.7300
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.1420
    Cell Significance Index: -14.7900
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.1514
    Cell Significance Index: -9.2800
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.1774
    Cell Significance Index: -14.0500
  • Cell Name: primitive red blood cell (CL0002355)
    Fold Change: -0.1837
    Cell Significance Index: -2.0800
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: -0.1915
    Cell Significance Index: -5.1300
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: -0.2075
    Cell Significance Index: -13.9500
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: -0.2122
    Cell Significance Index: -13.6900
  • Cell Name: inflammatory cell (CL0009002)
    Fold Change: -0.2145
    Cell Significance Index: -1.2300
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: -0.2305
    Cell Significance Index: -14.1700
  • Cell Name: cortical thymic epithelial cell (CL0002364)
    Fold Change: -0.2322
    Cell Significance Index: -1.9200
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: -0.2491
    Cell Significance Index: -13.9800
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: -0.2817
    Cell Significance Index: -14.7900
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: -0.2898
    Cell Significance Index: -8.1000
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: -0.3099
    Cell Significance Index: -8.2900
  • Cell Name: epithelial cell of uterus (CL0002149)
    Fold Change: -0.3261
    Cell Significance Index: -4.5300
  • Cell Name: peg cell (CL4033014)
    Fold Change: -0.3337
    Cell Significance Index: -7.7100
  • Cell Name: stratified epithelial cell (CL0000079)
    Fold Change: -0.3552
    Cell Significance Index: -13.0400
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: -0.3579
    Cell Significance Index: -15.8300
  • Cell Name: hippocampal astrocyte (CL0002604)
    Fold Change: -0.3611
    Cell Significance Index: -5.0500
  • Cell Name: connective tissue cell (CL0002320)
    Fold Change: -0.3620
    Cell Significance Index: -3.4900
  • Cell Name: BEST4+ enteroycte (CL4030026)
    Fold Change: -0.3663
    Cell Significance Index: -5.5200
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: -0.3689
    Cell Significance Index: -12.8200
  • Cell Name: astrocyte of the cerebral cortex (CL0002605)
    Fold Change: -0.3716
    Cell Significance Index: -6.4300
  • Cell Name: cardiac endothelial cell (CL0010008)
    Fold Change: -0.3921
    Cell Significance Index: -5.6400

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics** 1. **Function**: CSF1 is a growth factor that stimulates the proliferation and differentiation of cells, including macrophages, monocytes, and osteoclasts. 2. **Receptor**: CSF1 binds to its receptor, CSF1R, which is a transmembrane receptor tyrosine kinase. 3. **Signaling pathway**: The CSF1-CSF1R complex activates a signaling cascade that regulates cell proliferation, differentiation, and survival. 4. **Tissue expression**: CSF1 is significantly expressed in various tissues, including the mammary gland, immune cells, and connective tissue. 5. **Cell types**: CSF1 regulates the development and homeostasis of macrophages, monocytes, osteoclasts, and other cell types. **Pathways and Functions** 1. **Macrophage development and homeostasis**: CSF1 regulates the proliferation, differentiation, and survival of macrophages, which are essential for immune responses and tissue repair. 2. **Immune system**: CSF1 plays a key role in the development and function of immune cells, including macrophages, monocytes, and dendritic cells. 3. **Mammary gland development**: CSF1 regulates the development and homeostasis of the mammary gland, including the growth and differentiation of alveolar cells and ductal cells. 4. **Bone remodeling**: CSF1 regulates the development and function of osteoclasts, which are essential for bone resorption and remodeling. 5. **Neuroinflammation**: CSF1 regulates the development and function of microglial cells, which are essential for neuroinflammation and neurodegenerative diseases. **Clinical Significance** 1. **Cancer**: Abnormal expression of CSF1 has been linked to various cancers, including breast cancer, where it promotes tumor growth and metastasis. 2. **Autoimmune diseases**: CSF1 plays a key role in the development of autoimmune diseases, such as multiple sclerosis, where it regulates the development and function of immune cells. 3. **Immunodeficiency disorders**: CSF1 deficiency has been linked to immunodeficiency disorders, such as macrophage deficiency, where it regulates the development and function of macrophages. 4. **Bone disorders**: CSF1 regulates the development and function of osteoclasts, which are essential for bone remodeling, and abnormalities in CSF1 signaling have been linked to bone disorders, such as osteoporosis. In conclusion, the CSF1 gene plays a crucial role in the development, growth, and homeostasis of various tissues and organs, including the immune system, reproductive system, and mammary gland. Understanding the functions and pathways of CSF1 is essential for the development of novel therapeutic strategies for various diseases, including cancer, autoimmune diseases, and immunodeficiency disorders.

Genular Protein ID: 358682337

Symbol: CSF1_HUMAN

Name: Macrophage colony-stimulating factor 1

UniProtKB Accession Codes:

P09603 A8K6J5 Q13130 Q14086 Q14806 Q5VVF3 Q5VVF4 Q9UQR8

Database IDs:

ABCD 1 AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 3 CPTC 1 CTD 1 ChEMBL 1 ChiTaRS 1 DIP 1 DMDM 1 DNASU 1 DisGeNET 1 EMBL 14 Ensembl 4 EvolutionaryTrace 1 ExpressionAtlas 1 GO 54 Gene3D 1 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyConnect 1 GlyCosmos 1 GlyGen 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 2 KEGG 1 MANE-Select 1 MIM 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PDB 8 PDBsum 8 PIR 1 PIRSF 1 PRO 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 1 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 3 RNAct 1 Reactome 5 RefSeq 4 SIGNOR 1 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 2996129

Title: Molecular cloning of a complementary DNA encoding human macrophage-specific colony-stimulating factor (CSF-1).

PubMed ID: 2996129

DOI: 10.1126/science.2996129

PubMed ID: 3493529

Title: Human CSF-1: molecular cloning and expression of 4-kb cDNA encoding the human urinary protein.

PubMed ID: 3493529

DOI: 10.1126/science.3493529

PubMed ID: 2460758

Title: Human macrophage-colony stimulating factor: alternative RNA and protein processing from a single gene.

PubMed ID: 2460758

DOI: 10.1016/0161-5890(88)90112-5

PubMed ID: 2660794

Title: Amino-terminal region of human macrophage colony-stimulating factor (M-CSF) is sufficient for its in vitro biological activity: molecular cloning and expression of carboxyl-terminal deletion mutants of human M-CSF.

PubMed ID: 2660794

DOI: 10.1016/0006-291x(89)92683-1

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 16710414

Title: The DNA sequence and biological annotation of human chromosome 1.

PubMed ID: 16710414

DOI: 10.1038/nature04727

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 3500041

Title: Human CSF-1: gene structure and alternative splicing of mRNA precursors.

PubMed ID: 3500041

DOI: 10.1002/j.1460-2075.1987.tb02561.x

PubMed ID: 1791839

Title: Expression of colony-stimulating factor-1 (CSF-1) messenger RNA in human endometrial glands during the menstrual cycle: molecular cloning of a novel transcript that predicts a cell surface form of CSF-1.

PubMed ID: 1791839

DOI: 10.1210/mend-5-12-1931

PubMed ID: 8262907

Title: The structure of recombinant human carboxy-terminal-truncated macrophage colony-stimulating factor derived from mammalian cells.

PubMed ID: 8262907

DOI: 10.1093/oxfordjournals.jbchem.a124163

PubMed ID: 3498652

Title: Macrophage colony-stimulating factor purified from normal human urine. Amino-terminal sequence and amino acid composition.

PubMed ID: 3498652

DOI: 10.1016/0014-5793(87)80398-8

PubMed ID: 8051056

Title: Structural analysis of proteoglycan macrophage colony-stimulating factor.

PubMed ID: 8051056

DOI: 10.1016/s0021-9258(17)32085-9

PubMed ID: 3259875

Title: Macrophage colony-stimulating factor is produced by human T lymphoblastoid cell line, CEM-ON: identification by amino-terminal amino acid sequence analysis.

PubMed ID: 3259875

DOI: 10.1016/s0006-291x(88)80441-8

PubMed ID: 3039346

Title: Synthesis of membrane-bound colony-stimulating factor 1 (CSF-1) and downmodulation of CSF-1 receptors in NIH 3T3 cells transformed by cotransfection of the human CSF-1 and c-fms (CSF-1 receptor) genes.

PubMed ID: 3039346

DOI: 10.1128/mcb.7.7.2378-2387.1987

PubMed ID: 3264877

Title: Differential processing of colony-stimulating factor 1 precursors encoded by two human cDNAs.

PubMed ID: 3264877

DOI: 10.1128/mcb.8.11.5026-5034.1988

PubMed ID: 1531650

Title: Identification of a high molecular weight macrophage colony-stimulating factor as a glycosaminoglycan-containing species.

PubMed ID: 1531650

DOI: 10.1016/s0021-9258(18)42841-4

PubMed ID: 8422357

Title: Assignment of the inter- and intramolecular disulfide linkages in recombinant human macrophage colony stimulating factor using fast atom bombardment mass spectrometry.

PubMed ID: 8422357

DOI: 10.1021/bi00053a012

PubMed ID: 15519852

Title: CSF-1 regulation of the wandering macrophage: complexity in action.

PubMed ID: 15519852

DOI: 10.1016/j.tcb.2004.09.016

PubMed ID: 16337366

Title: Colony-stimulating factor-1 in immunity and inflammation.

PubMed ID: 16337366

DOI: 10.1016/j.coi.2005.11.006

PubMed ID: 18687298

Title: Macrophage colony stimulating factor: not just for macrophages anymore! A gateway into complex biologies.

PubMed ID: 18687298

DOI: 10.1016/j.intimp.2008.04.016

PubMed ID: 19934330

Title: Invasion of human breast cancer cells in vivo requires both paracrine and autocrine loops involving the colony-stimulating factor-1 receptor.

PubMed ID: 19934330

DOI: 10.1158/0008-5472.can-09-1868

PubMed ID: 20829061

Title: Macrophage-colony stimulating factor and interleukin-34 induce chemokines in human whole blood.

PubMed ID: 20829061

DOI: 10.1016/j.cyto.2010.08.005

PubMed ID: 20504948

Title: Functional overlap but differential expression of CSF-1 and IL-34 in their CSF-1 receptor-mediated regulation of myeloid cells.

PubMed ID: 20504948

DOI: 10.1189/jlb.1209822

PubMed ID: 22171320

Title: Human urinary glycoproteomics; attachment site specific analysis of N- and O-linked glycosylations by CID and ECD.

PubMed ID: 22171320

DOI: 10.1074/mcp.m111.013649

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 23234360

Title: LC-MS/MS characterization of O-glycosylation sites and glycan structures of human cerebrospinal fluid glycoproteins.

PubMed ID: 23234360

DOI: 10.1021/pr300963h

PubMed ID: 26091039

Title: A single kinase generates the majority of the secreted phosphoproteome.

PubMed ID: 26091039

DOI: 10.1016/j.cell.2015.05.028

PubMed ID: 1455231

Title: Three-dimensional structure of dimeric human recombinant macrophage colony-stimulating factor.

PubMed ID: 1455231

DOI: 10.1126/science.1455231

Sequence Information:

  • Length: 554
  • Mass: 60179
  • Checksum: 656B0894F9255AED
  • Sequence:
    • MTAPGAAGRC PPTTWLGSLL LLVCLLASRS ITEEVSEYCS HMIGSGHLQS LQRLIDSQME 
TSCQITFEFV DQEQLKDPVC YLKKAFLLVQ DIMEDTMRFR DNTPNAIAIV QLQELSLRLK 
SCFTKDYEEH DKACVRTFYE TPLQLLEKVK NVFNETKNLL DKDWNIFSKN CNNSFAECSS 
QDVVTKPDCN CLYPKAIPSS DPASVSPHQP LAPSMAPVAG LTWEDSEGTE GSSLLPGEQP 
LHTVDPGSAK QRPPRSTCQS FEPPETPVVK DSTIGGSPQP RPSVGAFNPG MEDILDSAMG 
TNWVPEEASG EASEIPVPQG TELSPSRPGG GSMQTEPARP SNFLSASSPL PASAKGQQPA 
DVTGTALPRV GPVRPTGQDW NHTPQKTDHP SALLRDPPEP GSPRISSLRP QGLSNPSTLS 
AQPQLSRSHS SGSVLPLGEL EGRRSTRDRR SPAEPEGGPA SEGAARPLPR FNSVPLTDTG 
HERQSEGSFS PQLQESVFHL LVPSVILVLL AVGGLLFYRW RRRSHQEPQR ADSPLEQPEG 
SPLTQDDRQV ELPV

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.