Details for: Fyn
Associated with
Other Information
Genular Protein ID: 4170865045
Symbol: FYN_MOUSE
Name: Tyrosine-protein kinase Fyn
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 2488273
Title: Expression of a novel form of the fyn proto-oncogene in hematopoietic cells.
PubMed ID: 2488273
PubMed ID: 9895129
Title: Two species of mRNAs for the fyn proto-oncogene are produced by an alternative polyadenylation.
PubMed ID: 9895129
PubMed ID: 16141072
Title: The transcriptional landscape of the mammalian genome.
PubMed ID: 16141072
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 1361685
Title: Impaired long-term potentiation, spatial learning, and hippocampal development in fyn mutant mice.
PubMed ID: 1361685
PubMed ID: 7681396
Title: Activation of Src family kinases by colony stimulating factor-1, and their association with its receptor.
PubMed ID: 7681396
PubMed ID: 8441403
Title: Differential effects of expression of the CD45 tyrosine protein phosphatase on the tyrosine phosphorylation of the lck, fyn, and c-src tyrosine protein kinases.
PubMed ID: 8441403
PubMed ID: 8413237
Title: Palmitylation of an amino-terminal cysteine motif of protein tyrosine kinases p56lck and p59fyn mediates interaction with glycosyl-phosphatidylinositol-anchored proteins.
PubMed ID: 8413237
PubMed ID: 7980442
Title: Palmitoylation of multiple Src-family kinases at a homologous N-terminal motif.
PubMed ID: 7980442
DOI: 10.1042/bj3030749
PubMed ID: 8168489
Title: Analysis of Ig-alpha-tyrosine kinase interaction reveals two levels of binding specificity and tyrosine phosphorylated Ig-alpha stimulation of Fyn activity.
PubMed ID: 8168489
PubMed ID: 8007959
Title: Unique catalytic properties dictate the enhanced function of p59fynT, the hemopoietic cell-specific isoform of the Fyn tyrosine protein kinase, in T cells.
PubMed ID: 8007959
PubMed ID: 8655574
Title: Multiple features of the p59fyn src homology 4 domain define a motif for immune-receptor tyrosine-based activation motif (ITAM) binding and for plasma membrane localization.
PubMed ID: 8655574
PubMed ID: 9312046
Title: Sequential activation of phoshatidylinositol 3-kinase and phospholipase C-gamma2 by the M-CSF receptor is necessary for differentiation signaling.
PubMed ID: 9312046
PubMed ID: 9201723
Title: Palmitoylation of p59fyn is reversible and sufficient for plasma membrane association.
PubMed ID: 9201723
DOI: 10.1091/mbc.8.6.1159
PubMed ID: 11711534
Title: 'Srcasm: a novel Src activating and signaling molecule.
PubMed ID: 11711534
PubMed ID: 12218089
Title: Fyn is essential for tyrosine phosphorylation of Csk-binding protein/phosphoprotein associated with glycolipid-enriched microdomains in lipid rafts in resting T cells.
PubMed ID: 12218089
PubMed ID: 12681493
Title: Targeting of MIST to Src-family kinases via SKAP55-SLAP-130 adaptor complex in mast cells(1).
PubMed ID: 12681493
PubMed ID: 12640114
Title: p120 Catenin-associated Fer and Fyn tyrosine kinases regulate beta-catenin Tyr-142 phosphorylation and beta-catenin-alpha-catenin Interaction.
PubMed ID: 12640114
PubMed ID: 14645715
Title: Transmembrane phosphoprotein Cbp senses cell adhesion signaling mediated by Src family kinase in lipid rafts.
PubMed ID: 14645715
PubMed ID: 14999081
Title: Phosphorylation of tau by fyn: implications for Alzheimer's disease.
PubMed ID: 14999081
PubMed ID: 16129412
Title: Signaling by Kit protein-tyrosine kinase--the stem cell factor receptor.
PubMed ID: 16129412
PubMed ID: 16966330
Title: Phosphorylation of Tyr1214 within VEGFR-2 triggers the recruitment of Nck and activation of Fyn leading to SAPK2/p38 activation and endothelial cell migration in response to VEGF.
PubMed ID: 16966330
PubMed ID: 18034455
Title: Large-scale identification and evolution indexing of tyrosine phosphorylation sites from murine brain.
PubMed ID: 18034455
DOI: 10.1021/pr0701254
PubMed ID: 19144319
Title: The phagosomal proteome in interferon-gamma-activated macrophages.
PubMed ID: 19144319
PubMed ID: 19956733
Title: Palmitoylation regulates epidermal homeostasis and hair follicle differentiation.
PubMed ID: 19956733
PubMed ID: 21183079
Title: A tissue-specific atlas of mouse protein phosphorylation and expression.
PubMed ID: 21183079
PubMed ID: 20398064
Title: Tyrosine phosphorylation of R3 subtype receptor-type protein tyrosine phosphatases and their complex formations with Grb2 or Fyn.
PubMed ID: 20398064
PubMed ID: 21872217
Title: Decreased dendritic spine density and abnormal spine morphology in Fyn knockout mice.
PubMed ID: 21872217
PubMed ID: 22685302
Title: Down syndrome cell adhesion molecule (DSCAM) associates with uncoordinated-5C (UNC5C) in netrin-1-mediated growth cone collapse.
PubMed ID: 22685302
Sequence Information:
- Length: 537
- Mass: 60675
- Checksum: 99558702596DAEE0
- Sequence:
MGCVQCKDKE AAKLTEERDG SLNQSSGYRY GTDPTPQHYP SFGVTSIPNY NNFHAAGGQG LTVFGGVNSS SHTGTLRTRG GTGVTLFVAL YDYEARTEDD LSFHKGEKFQ ILNSSEGDWW EARSLTTGET GYIPSNYVAP VDSIQAEEWY FGKLGRKDAE RQLLSFGNPR GTFLIRESET TKGAYSLSIR DWDDMKGDHV KHYKIRKLDN GGYYITTRAQ FETLQQLVQH YSERAAGLCC RLVVPCHKGM PRLTDLSVKT KDVWEIPRES LQLIKRLGNG QFGEVWMGTW NGNTKVAIKT LKPGTMSPES FLEEAQIMKK LKHDKLVQLY AVVSEEPIYI VTEYMSKGSL LDFLKDGEGR ALKLPNLVDM AAQVAAGMAY IERMNYIHRD LRSANILVGN GLICKIADFG LARLIEDNEY TARQGAKFPI KWTAPEAALY GRFTIKSDVW SFGILLTELV TKGRVPYPGM NNREVLEQVE RGYRMPCPQD CPISLHELMI HCWKKDPEER PTFEYLQGFL EDYFTATEPQ YQPGENL
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.