Genular: Defining Cellular Identity and Function

Details for: Fzd1

Gene ID: 14362

Symbol: Fzd1

Ensembl ID: ENSMUSG00000044674

Description: frizzled class receptor 1

Associated with

Asymmetric localization of pcp proteins
(R-MMU-4608870)
Beta-catenin independent wnt signaling
(R-MMU-3858494)
Disassembly of the destruction complex and recruitment of axin to the membrane
(R-MMU-4641262)
Pcp/ce pathway
(R-MMU-4086400)
Signaling by wnt
(R-MMU-195721)
Tcf dependent signaling in response to wnt
(R-MMU-201681)
Autocrine signaling
(GO:0035425)
Canonical wnt signaling pathway
(GO:0060070)
Canonical wnt signaling pathway involved in mesenchymal stem cell differentiation
(GO:0044338)
Cell-cell signaling
(GO:0007267)
Cell surface
(GO:0009986)
Cell surface receptor signaling pathway
(GO:0007166)
Endothelial cell differentiation
(GO:0045446)
Frizzled binding
(GO:0005109)
G protein-coupled receptor activity
(GO:0004930)
G protein-coupled receptor signaling pathway
(GO:0007186)
Hard palate development
(GO:0060022)
Identical protein binding
(GO:0042802)
Membrane
(GO:0016020)
Membranous septum morphogenesis
(GO:0003149)
Multicellular organism development
(GO:0007275)
Muscular septum morphogenesis
(GO:0003150)
Negative regulation of bmp signaling pathway
(GO:0030514)
Negative regulation of canonical wnt signaling pathway
(GO:0090090)
Negative regulation of dna-templated transcription
(GO:0045892)
Negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway
(GO:1903377)
Non-canonical wnt signaling pathway
(GO:0035567)
Outflow tract morphogenesis
(GO:0003151)
Pdz domain binding
(GO:0030165)
Planar cell polarity pathway involved in neural tube closure
(GO:0090179)
Plasma membrane
(GO:0005886)
Positive regulation of dna-binding transcription factor activity
(GO:0051091)
Positive regulation of dna-templated transcription
(GO:0045893)
Positive regulation of neuron projection development
(GO:0010976)
Positive regulation of osteoblast differentiation
(GO:0045669)
Positive regulation of protein phosphorylation
(GO:0001934)
Protein heterodimerization activity
(GO:0046982)
Protein homodimerization activity
(GO:0042803)
Regulation of mesenchymal stem cell differentiation
(GO:2000739)
Regulation of presynapse assembly
(GO:1905606)
Response to xenobiotic stimulus
(GO:0009410)
Signaling receptor binding
(GO:0005102)
Signal transduction
(GO:0007165)
Transmembrane signaling receptor activity
(GO:0004888)
Ventricular septum morphogenesis
(GO:0060412)
Wnt-protein binding
(GO:0017147)
Wnt receptor activity
(GO:0042813)
Wnt signaling pathway
(GO:0016055)

Other Information

Proteins

Frizzled-1

Genular Protein ID: 3066640041

Symbol: FZD1_MOUSE

Name: Frizzled-1

UniProtKB Accession Codes:

O70421 O08974 Q7TS82

Database IDs:

Citations:

PubMed ID: 11334716

Title: Expression of frizzled genes in mouse costochondral chondrocytes.

PubMed ID: 11334716

DOI: 10.1016/s0945-053x(00)00138-4

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 15923619

Title: Wnt7b activates canonical signaling in epithelial and vascular smooth muscle cells through interactions with Fzd1, Fzd10, and LRP5.

PubMed ID: 15923619

DOI: 10.1128/mcb.25.12.5022-5030.2005

Sequence Information:

Length: 642
Mass: 71127
Checksum: 7674583F819014E2
Sequence:

MAEEAAPSES RAAGRLSLEL CAEALPGRRE EVGHEDTASH RRPRADPRRW ASGLLLLLWL 
LEAPLLLGVR AQAAGQVSGP GQQAPPPPQP QQSGQQYNGE RGISIPDHGY CQPISIPLCT 
DIAYNQTIMP NLLGHTNQED AGLEVHQFYP LVKVQCSAEL KFFLCSMYAP VCTVLEQALP 
PCRSLCERAR QGCEALMNKF GFQWPDTLKC EKFPVHGAGE LCVGQNTSDK GTPTPSLLPE 
FWTSNPQHGG GGYRGGYPGG AGTVERGKFS CPRALRVPSY LNYHFLGEKD CGAPCEPTKV 
YGLMYFGPEE LRFSRTWIGI WSVLCCASTL FTVLTYLVDM RRFSYPERPI IFLSGCYTAV 
AVAYIAGFLL EDRVVCNDKF AEDGARTVAQ GTKKEGCTIL FMMLYFFSMA SSIWWVILSL 
TWFLAAGMKW GHEAIEANSQ YFHLAAWAVP AIKTITILAL GQVDGDVLSG VCFVGLNNVD 
ALRGFVLAPL FVYLFIGTSF LLAGFVSLFR IRTIMKHDGT KTEKLEKLMV RIGVFSVLYT 
VPATIVIACY FYEQAFRDQW ERSWVAQSCK SYAIPCPHLQ GGGGVPPHPP MSPDFTVFMI 
KYLMTLIVGI TSGFWIWSGK TLNSWRKFYT RLTNSKQGET TV

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Fzd1

Associated with

Other Information

Expression of frizzled genes in mouse costochondral chondrocytes. PubMed ID: 11334716

The transcriptional landscape of the mammalian genome. PubMed ID: 16141072

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Wnt7b activates canonical signaling in epithelial and vascular smooth muscle cells through interactions with Fzd1, Fzd10, and LRP5. PubMed ID: 15923619

Database document:

PubMed ID: 11334716

PubMed ID: 16141072

PubMed ID: 15489334

PubMed ID: 15923619