Details for: Fzd3

Gene ID: 14365

Symbol: Fzd3

Ensembl ID: ENSMUSG00000007989

Description: frizzled class receptor 3

Associated with

Other Information

Genular Protein ID: 3285045129

Symbol: FZD3_MOUSE

Name: Frizzled-3

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 8626800

Title: A large family of putative transmembrane receptors homologous to the product of the Drosophila tissue polarity gene frizzled.

PubMed ID: 8626800

DOI: 10.1074/jbc.271.8.4468

PubMed ID: 10395542

Title: Protein kinase C is differentially stimulated by Wnt and Frizzled homologs in a G-protein-dependent manner.

PubMed ID: 10395542

DOI: 10.1016/s0960-9822(99)80310-8

PubMed ID: 11407985

Title: Characterization of mouse frizzled-3 expression in hair follicle development and identification of the human homolog in keratinocytes.

PubMed ID: 11407985

DOI: 10.1046/j.1523-1747.2001.01336.x

PubMed ID: 12351730

Title: Frizzled-3 is required for the development of major fiber tracts in the rostral CNS.

PubMed ID: 12351730

DOI: 10.1523/jneurosci.22-19-08563.2002

PubMed ID: 14671310

Title: Anterior-posterior guidance of commissural axons by Wnt-frizzled signaling.

PubMed ID: 14671310

DOI: 10.1126/science.1089610

PubMed ID: 16407530

Title: Axonal growth and guidance defects in Frizzled3 knock-out mice: a comparison of diffusion tensor magnetic resonance imaging, neurofilament staining, and genetically directed cell labeling.

PubMed ID: 16407530

DOI: 10.1523/jneurosci.3221-05.2006

PubMed ID: 16495441

Title: The role of Frizzled3 and Frizzled6 in neural tube closure and in the planar polarity of inner-ear sensory hair cells.

PubMed ID: 16495441

DOI: 10.1523/jneurosci.4698-05.2005

PubMed ID: 16687519

Title: Asymmetric localization of Vangl2 and Fz3 indicate novel mechanisms for planar cell polarity in mammals.

PubMed ID: 16687519

DOI: 10.1523/jneurosci.4680-05.2006

PubMed ID: 21325504

Title: Frizzled3 is required for neurogenesis and target innervation during sympathetic nervous system development.

PubMed ID: 21325504

DOI: 10.1523/jneurosci.4243-10.2011

PubMed ID: 24347548

Title: Frizzled3 controls axonal development in distinct populations of cranial and spinal motor neurons.

PubMed ID: 24347548

DOI: 10.7554/elife.01482

PubMed ID: 24799694

Title: Frizzled3 is required for the development of multiple axon tracts in the mouse central nervous system.

PubMed ID: 24799694

DOI: 10.1073/pnas.1406399111

Sequence Information:

  • Length: 666
  • Mass: 76208
  • Checksum: 0920038B79A73335
  • Sequence:
  • MAVSWIVFDL WLLTVFLGQI GGHSLFSCEP ITLRMCQDLP YNTTFMPNLL NHYDQQTAAL 
    AMEPFHPMVN LDCSRDFRPF LCALYAPICM EYGRVTLPCR RLCQRAYSEC SKLMEMFGVP 
    WPEDMECSRF PDCDEPYPRL VDLNLVGDPT EGAPVAVQRD YGFWCPRELK IDPDLGYSFL 
    HVRDCSPPCP NMYFRREELS FARYFIGLIS IICLSATLFT FLTFLIDVTR FRYPERPIIF 
    YAVCYMMVSL IFFIGFLLED RVACNASSPA QYKASTVTQG SHNKACTMLF MVLYFFTMAG 
    SVWWVILTIT WFLAAVPKWG SEAIEKKALL FHASAWGIPG TLTIILLAMN KIEGDNISGV 
    CFVGLYDVDA LRYFVLAPLC LYVVVGVSLL LAGIISLNRV RIEIPLEKEN QDKLVKFMIR 
    IGVFSILYLV PLLVVIGCYF YEQAYRGIWE TTWIQERCRE YHIPCPYQVT QMSRPDLILF 
    LMKYLMALIV GIPSIFWVGS KKTCFEWASF FHGRRKKEIV NESRQVLQEP DFAQSLLRDP 
    NTPIIRKSRG TSTQGTSTHA SSTQLAMVDD QRSKAGSVHS KVSSYHGSLH RSRDGRYTPC 
    SYRGMEERLP HGSMSRLTDH SRHSSSHRLN EQSRHSSIRD LSNNPMTHIT HGTSMNRVIE 
    EDGTSA

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.