Genular: Defining Cellular Identity and Function

Details for: G6pdx

Gene ID: 14381

Symbol: G6pdx

Ensembl ID: ENSMUSG00000031400

Description: glucose-6-phosphate dehydrogenase X-linked

Associated with

Gene expression (transcription)
(R-MMU-74160)
Generic transcription pathway
(R-MMU-212436)
Metabolism
(R-MMU-1430728)
Metabolism of carbohydrates
(R-MMU-71387)
Pentose phosphate pathway
(R-MMU-71336)
Rna polymerase ii transcription
(R-MMU-73857)
Tp53 regulates metabolic genes
(R-MMU-5628897)
Transcriptional regulation by tp53
(R-MMU-3700989)
Angiotensin-mediated vasoconstriction involved in regulation of systemic arterial blood pressure
(GO:0001998)
Angiotensin-mediated vasodilation involved in regulation of systemic arterial blood pressure
(GO:0002033)
Carbohydrate binding
(GO:0030246)
Carbohydrate metabolic process
(GO:0005975)
Cellular response to oxidative stress
(GO:0034599)
Centriolar satellite
(GO:0034451)
Cholesterol biosynthetic process
(GO:0006695)
Cytokine production
(GO:0001816)
Cytoplasm
(GO:0005737)
Cytoplasmic side of plasma membrane
(GO:0009898)
Cytosol
(GO:0005829)
Erythrocyte development
(GO:0048821)
Erythrocyte maturation
(GO:0043249)
Glucose-6-phosphate dehydrogenase activity
(GO:0004345)
Glucose 6-phosphate metabolic process
(GO:0051156)
Glucose binding
(GO:0005536)
Glucose metabolic process
(GO:0006006)
Glutathione metabolic process
(GO:0006749)
Identical protein binding
(GO:0042802)
Interleukin-10 production
(GO:0032613)
Interleukin-12 production
(GO:0032615)
Intracellular membrane-bounded organelle
(GO:0043231)
Membrane
(GO:0016020)
Nadp binding
(GO:0050661)
Nadp biosynthetic process
(GO:0006741)
Nadph regeneration
(GO:0006740)
Nadp metabolic process
(GO:0006739)
Negative regulation of cell growth involved in cardiac muscle cell development
(GO:0061052)
Negative regulation of protein glutathionylation
(GO:0010734)
Negative regulation of reactive oxygen species metabolic process
(GO:2000378)
Oxidoreductase activity
(GO:0016491)
Oxidoreductase activity, acting on ch-oh group of donors
(GO:0016614)
Pentose-phosphate shunt
(GO:0006098)
Pentose-phosphate shunt, oxidative branch
(GO:0009051)
Pentose biosynthetic process
(GO:0019322)
Positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel
(GO:1904879)
Protein homodimerization activity
(GO:0042803)
Regulation of multicellular organism growth
(GO:0040014)
Regulation of neuron apoptotic process
(GO:0043523)
Response to ethanol
(GO:0045471)
Response to oxidative stress
(GO:0006979)
Ribose phosphate biosynthetic process
(GO:0046390)

Other Information

Proteins

Glucose-6-phosphate 1-dehydrogenase X

Genular Protein ID: 108261463

Symbol: G6PD1_MOUSE

Name: Glucose-6-phosphate 1-dehydrogenase X

UniProtKB Accession Codes:

Q00612

Database IDs:

Citations:

PubMed ID: 8400362

Title: Sequence of mouse glucose-6-phosphate dehydrogenase cDNA.

PubMed ID: 8400362

DOI: 10.3109/10425179309020830

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 1874446

Title: The CpG island in the 5' region of the G6PD gene of man and mouse.

PubMed ID: 1874446

DOI: 10.1016/0378-1119(91)90078-p

PubMed ID: 9330624

Title: Somatic mutation of the glucose-6-phosphate dehydrogenase (g6pd) gene in colonic stem cells and crypt restricted loss of G6PD activity.

PubMed ID: 9330624

DOI: 10.1016/s0027-5107(97)00109-7

PubMed ID: 12831846

Title: Murine hexose-6-phosphate dehydrogenase: a bifunctional enzyme with broad substrate specificity and 6-phosphogluconolactonase activity.

PubMed ID: 12831846

DOI: 10.1016/s0003-9861(03)00229-7

PubMed ID: 17947660

Title: Quantitative time-resolved phosphoproteomic analysis of mast cell signaling.

PubMed ID: 17947660

DOI: 10.4049/jimmunol.179.9.5864

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

PubMed ID: 35122041

Title: Aldolase B suppresses hepatocellular carcinogenesis by inhibiting G6PD and pentose phosphate pathways.

PubMed ID: 35122041

DOI: 10.1038/s43018-020-0086-7

Sequence Information:

Length: 515
Mass: 59263
Checksum: C8AF0D4099B7AEC3
Sequence:

MAEQVALSRT QVCGILREEL YQGDAFHQAD THIFIIMGAS GDLAKKKIYP TIWWLFRDGL 
LPEDTFIVGY ARSRLTVDDI RKQSEPFFKA TPEERPKLEE FFARNSYVAG QYDDAASYKH 
LNSHMNALHQ GMQANRLFYL ALPPTVYEAV TKNIQETCMS QTGWNRIIVE KPFGRDLQSS 
NQLSNHISSL FREDQIYRID HYLGKEMVQN LMVLRFANRI FGPIWNRDNI ACVILTFKEP 
FGTEGRGGYF DEFGIIRDVM QNHLLQMLCL VAMEKPATTG SDDVRDEKVK VLKCISEVET 
DNVVLGQYVG NPNGEGEAAN GYLDDPTVPH GSTTATFAAA VLYVENERWD GVPFILRCGK 
ALNERKAEVR LQFRDVAGDI FHQQCKRNEL VIRVQPNEAV YTKMMTKKPG MFFNPEESEL 
DLTYGNRYKN VKLPDAYERL ILDVFCGSQM HFVRSDELRE AWRIFTPLLH KIDREKPQPI 
PYVYGSRGPT EADELMKRVG FQYEGTYKWV NPHKL

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: G6pdx

Associated with

Other Information

Sequence of mouse glucose-6-phosphate dehydrogenase cDNA. PubMed ID: 8400362

The transcriptional landscape of the mammalian genome. PubMed ID: 16141072

The CpG island in the 5' region of the G6PD gene of man and mouse. PubMed ID: 1874446

Somatic mutation of the glucose-6-phosphate dehydrogenase (g6pd) gene in colonic stem cells and crypt restricted loss of G6PD activity. PubMed ID: 9330624

Murine hexose-6-phosphate dehydrogenase: a bifunctional enzyme with broad substrate specificity and 6-phosphogluconolactonase activity. PubMed ID: 12831846

Quantitative time-resolved phosphoproteomic analysis of mast cell signaling. PubMed ID: 17947660

A tissue-specific atlas of mouse protein phosphorylation and expression. PubMed ID: 21183079

Aldolase B suppresses hepatocellular carcinogenesis by inhibiting G6PD and pentose phosphate pathways. PubMed ID: 35122041