Details for: CSF2RB

Gene ID: 1439

Symbol: CSF2RB

Ensembl ID: ENSG00000100368

Description: colony stimulating factor 2 receptor subunit beta

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 58.4717
    Cell Significance Index: -9.1000
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 36.6262
    Cell Significance Index: -9.2900
  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 21.1935
    Cell Significance Index: -8.6100
  • Cell Name: peripheral blood mononuclear cell (CL2000001)
    Fold Change: 19.3046
    Cell Significance Index: -9.9300
  • Cell Name: transit amplifying cell of small intestine (CL0009012)
    Fold Change: 8.2274
    Cell Significance Index: 170.6700
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 7.9800
    Cell Significance Index: 280.4100
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 7.5631
    Cell Significance Index: -9.3300
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: 4.1855
    Cell Significance Index: 104.6300
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: 2.9566
    Cell Significance Index: 64.0600
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: 2.5799
    Cell Significance Index: 82.6300
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 2.4480
    Cell Significance Index: -9.6600
  • Cell Name: fallopian tube secretory epithelial cell (CL4030006)
    Fold Change: 2.4251
    Cell Significance Index: 37.5200
  • Cell Name: endothelial cell of venule (CL1000414)
    Fold Change: 2.4207
    Cell Significance Index: 27.5000
  • Cell Name: extravillous trophoblast (CL0008036)
    Fold Change: 2.0890
    Cell Significance Index: 12.9800
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 1.0334
    Cell Significance Index: 196.6700
  • Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
    Fold Change: 0.9311
    Cell Significance Index: 17.2100
  • Cell Name: Hofbauer cell (CL3000001)
    Fold Change: 0.7284
    Cell Significance Index: 5.9400
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.6464
    Cell Significance Index: 63.9500
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: 0.6067
    Cell Significance Index: 12.9200
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.5172
    Cell Significance Index: 467.0400
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: 0.4095
    Cell Significance Index: 21.3300
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 0.3816
    Cell Significance Index: 41.5100
  • Cell Name: primitive red blood cell (CL0002355)
    Fold Change: 0.3560
    Cell Significance Index: 4.0300
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.3478
    Cell Significance Index: 56.5700
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: 0.3330
    Cell Significance Index: 19.9900
  • Cell Name: vascular lymphangioblast (CL0005022)
    Fold Change: 0.2756
    Cell Significance Index: 4.8700
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: 0.2557
    Cell Significance Index: 30.1600
  • Cell Name: retinal blood vessel endothelial cell (CL0002585)
    Fold Change: 0.1285
    Cell Significance Index: 1.6600
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: 0.0579
    Cell Significance Index: 36.1600
  • Cell Name: basophil mast progenitor cell (CL0002028)
    Fold Change: 0.0231
    Cell Significance Index: 0.2000
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: 0.0004
    Cell Significance Index: 0.0100
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0001
    Cell Significance Index: -0.0600
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.0006
    Cell Significance Index: -0.1300
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0008
    Cell Significance Index: -0.4500
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: -0.0047
    Cell Significance Index: -8.7600
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: -0.0066
    Cell Significance Index: -0.1900
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: -0.0082
    Cell Significance Index: -15.2000
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: -0.0098
    Cell Significance Index: -1.6800
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: -0.0099
    Cell Significance Index: -15.2000
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: -0.0113
    Cell Significance Index: -15.4200
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0122
    Cell Significance Index: -9.2600
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: -0.0125
    Cell Significance Index: -7.9200
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.0131
    Cell Significance Index: -1.5100
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: -0.0161
    Cell Significance Index: -0.7300
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0228
    Cell Significance Index: -10.3700
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: -0.0258
    Cell Significance Index: -9.2700
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.0313
    Cell Significance Index: -9.0100
  • Cell Name: trophoblast giant cell (CL0002488)
    Fold Change: -0.0319
    Cell Significance Index: -0.2300
  • Cell Name: fibro/adipogenic progenitor cell (CL0009099)
    Fold Change: -0.0332
    Cell Significance Index: -1.6800
  • Cell Name: odontoblast (CL0000060)
    Fold Change: -0.0369
    Cell Significance Index: -4.7300
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: -0.0371
    Cell Significance Index: -7.3600
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: -0.0413
    Cell Significance Index: -7.4500
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: -0.0425
    Cell Significance Index: -8.5400
  • Cell Name: eukaryotic cell (CL0000255)
    Fold Change: -0.0439
    Cell Significance Index: -1.9100
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.0515
    Cell Significance Index: -3.1600
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.0526
    Cell Significance Index: -5.3700
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.0528
    Cell Significance Index: -7.6800
  • Cell Name: pancreatic endocrine cell (CL0008024)
    Fold Change: -0.0541
    Cell Significance Index: -6.1800
  • Cell Name: megakaryocyte progenitor cell (CL0000553)
    Fold Change: -0.0560
    Cell Significance Index: -0.4000
  • Cell Name: BEST4+ enteroycte (CL4030026)
    Fold Change: -0.0584
    Cell Significance Index: -0.8800
  • Cell Name: neuron associated cell (CL0000095)
    Fold Change: -0.0637
    Cell Significance Index: -2.6100
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: -0.0675
    Cell Significance Index: -1.8100
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: -0.0741
    Cell Significance Index: -9.1100
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: -0.0772
    Cell Significance Index: -10.6000
  • Cell Name: lactocyte (CL0002325)
    Fold Change: -0.0802
    Cell Significance Index: -10.3600
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.0916
    Cell Significance Index: -9.5400
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: -0.0966
    Cell Significance Index: -6.2300
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: -0.1354
    Cell Significance Index: -10.0900
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: -0.1371
    Cell Significance Index: -10.5200
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: -0.1481
    Cell Significance Index: -9.9600
  • Cell Name: myeloid leukocyte (CL0000766)
    Fold Change: -0.1562
    Cell Significance Index: -1.2700
  • Cell Name: hematopoietic cell (CL0000988)
    Fold Change: -0.1597
    Cell Significance Index: -2.3400
  • Cell Name: proerythroblast (CL0000547)
    Fold Change: -0.1647
    Cell Significance Index: -2.3600
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: -0.1848
    Cell Significance Index: -11.3600
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: -0.1881
    Cell Significance Index: -8.8400
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: -0.1909
    Cell Significance Index: -10.7100
  • Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
    Fold Change: -0.2000
    Cell Significance Index: -5.8800
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: -0.2004
    Cell Significance Index: -5.6000
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: -0.2023
    Cell Significance Index: -9.4300
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: -0.2089
    Cell Significance Index: -5.3700
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: -0.2119
    Cell Significance Index: -11.0100
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: -0.2175
    Cell Significance Index: -11.4200
  • Cell Name: helper T cell (CL0000912)
    Fold Change: -0.2224
    Cell Significance Index: -3.1600
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: -0.2337
    Cell Significance Index: -8.1200
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: -0.2443
    Cell Significance Index: -8.5600
  • Cell Name: fibroblast of dermis (CL0002551)
    Fold Change: -0.2460
    Cell Significance Index: -5.1500
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: -0.2552
    Cell Significance Index: -11.2900
  • Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
    Fold Change: -0.2591
    Cell Significance Index: -3.7100
  • Cell Name: CD14-positive monocyte (CL0001054)
    Fold Change: -0.2608
    Cell Significance Index: -5.1000
  • Cell Name: myeloid cell (CL0000763)
    Fold Change: -0.2845
    Cell Significance Index: -3.7800
  • Cell Name: immature innate lymphoid cell (CL0001082)
    Fold Change: -0.2886
    Cell Significance Index: -3.5700
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -0.2896
    Cell Significance Index: -9.4800
  • Cell Name: leukocyte (CL0000738)
    Fold Change: -0.2909
    Cell Significance Index: -4.9400
  • Cell Name: stratified epithelial cell (CL0000079)
    Fold Change: -0.2930
    Cell Significance Index: -10.7600
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -0.2992
    Cell Significance Index: -9.5300
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: -0.3003
    Cell Significance Index: -11.3700
  • Cell Name: kidney epithelial cell (CL0002518)
    Fold Change: -0.3198
    Cell Significance Index: -9.4200
  • Cell Name: CD14-low, CD16-positive monocyte (CL0002396)
    Fold Change: -0.3261
    Cell Significance Index: -7.9000
  • Cell Name: erythrocyte (CL0000232)
    Fold Change: -0.3379
    Cell Significance Index: -8.6100
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: -0.3389
    Cell Significance Index: -9.0800

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics** * CSF2RB is a gene that encodes a subunit of the GM-CSF receptor, which is essential for the production and function of granulocytes and macrophages. * The gene is significantly expressed in various cell types, including myeloid leukocytes, enterocytes, and basophils. * CSF2RB is involved in the regulation of immune responses, inflammation, and surfactant metabolism. * Mutations in the CSF2RB gene have been associated with several diseases, including surfactant metabolism disorders and immunodeficiency syndromes. **Pathways and Functions** * **Cytokine-mediated signaling pathway**: CSF2RB is involved in the signaling pathway of granulocyte-macrophage colony-stimulating factor (GM-CSF), which regulates the production and function of granulocytes and macrophages. * **Coreceptor activity**: CSF2RB acts as a coreceptor for GM-CSF, which is essential for the binding of GM-CSF to its receptor and the subsequent signaling cascade. * **Cytokine receptor activity**: CSF2RB is involved in the regulation of cytokine signaling, including the signaling pathways of interleukin-3 (IL-3), IL-5, and GM-CSF. * **Signaling by interleukins**: CSF2RB is involved in the signaling pathways of IL-3, IL-5, and GM-CSF, which regulate the production and function of granulocytes and macrophages. **Clinical Significance** * **Surfactant metabolism disorders**: Mutations in the CSF2RB gene have been associated with surfactant metabolism disorders, which are characterized by impaired surfactant production and function, leading to respiratory distress and other complications. * **Immunodeficiency syndromes**: CSF2RB mutations have also been associated with immunodeficiency syndromes, which are characterized by impaired immune function and increased susceptibility to infections. * **Inflammation and immune responses**: CSF2RB plays a crucial role in the regulation of immune responses and inflammation, making it a potential target for the treatment of inflammatory and autoimmune diseases. * **Cancer**: CSF2RB has been implicated in the development and progression of various cancers, including leukemia and lymphoma, highlighting its potential as a therapeutic target. In conclusion, the CSF2RB gene plays a crucial role in the regulation of the immune system, inflammation, and surfactant metabolism. Its significance in the development and progression of various diseases, including surfactant metabolism disorders, immunodeficiency syndromes, and cancer, highlights its importance as a therapeutic target. Further research is needed to fully understand the mechanisms of CSF2RB and its role in human disease.

Genular Protein ID: 1404934905

Symbol: IL3RB_HUMAN

Name: Cytokine receptor common subunit beta

UniProtKB Accession Codes:

P32927 Q5JZI1 Q6ICE0

Database IDs:

ABCD 1 AGR 1 AlphaFoldDB 1 Antibodypedia 1 BMRB 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 2 CDD 1 CORUM 1 CTD 1 ChEMBL 2 ChiTaRS 1 ComplexPortal 2 DIP 1 DMDM 1 DNASU 1 DisGeNET 1 DrugBank 3 DrugCentral 1 ELM 1 EMBL 6 EMDB 3 Ensembl 2 EvolutionaryTrace 1 ExpressionAtlas 1 GO 17 Gene3D 1 GeneCards 1 GeneTree 1 GenomeRNAi 1 GlyCosmos 1 GlyGen 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 6 KEGG 1 MANE-Select 1 MIM 3 MINT 1 MalaCards 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 Orphanet 1 OrthoDB 1 PANTHER 2 PDB 9 PDBsum 9 PIR 1 PIRSF 1 PRO 1 PROSITE 2 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 1 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 2 RNAct 1 Reactome 6 RefSeq 2 SIGNOR 1 SMART 1 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 1702217

Title: Molecular cloning of a second subunit of the receptor for human granulocyte-macrophage colony-stimulating factor (GM-CSF): reconstitution of a high-affinity GM-CSF receptor.

PubMed ID: 1702217

DOI: 10.1073/pnas.87.24.9655

PubMed ID: 15461802

Title: A genome annotation-driven approach to cloning the human ORFeome.

PubMed ID: 15461802

DOI: 10.1186/gb-2004-5-10-r84

PubMed ID: 10591208

Title: The DNA sequence of human chromosome 22.

PubMed ID: 10591208

DOI: 10.1038/990031

PubMed ID: 17828305

Title: CBAP interacts with the un-liganded common beta-subunit of the GM-CSF/IL-3/IL-5 receptor and induces apoptosis via mitochondrial dysfunction.

PubMed ID: 17828305

DOI: 10.1038/sj.onc.1210778

PubMed ID: 21075760

Title: Adult-onset hereditary pulmonary alveolar proteinosis caused by a single-base deletion in CSF2RB.

PubMed ID: 21075760

DOI: 10.1136/jmg.2010.082586

PubMed ID: 1495999

Title: Molecular basis of the membrane-anchored and two soluble isoforms of the human interleukin 5 receptor alpha subunit.

PubMed ID: 1495999

DOI: 10.1073/pnas.89.15.7041

PubMed ID: 9516124

Title: JAK2 and JAK1 constitutively associate with an interleukin-5 (IL-5) receptor alpha and betac subunit, respectively, and are activated upon IL-5 stimulation.

PubMed ID: 9516124

PubMed ID: 10736232

Title: The solution structure of the cytokine-binding domain of the common beta-chain of the receptors for granulocyte-macrophage colony-stimulating factor, interleukin-3 and interleukin-5.

PubMed ID: 10736232

DOI: 10.1006/jmbi.2000.3610

PubMed ID: 10753826

Title: Structure of the activation domain of the GM-CSF/IL-3/IL-5 receptor common beta-chain bound to an antagonist.

PubMed ID: 10753826

PubMed ID: 11207369

Title: Structure of the complete extracellular domain of the common beta subunit of the human GM-CSF, IL-3, and IL-5 receptors reveals a novel dimer configuration.

PubMed ID: 11207369

DOI: 10.1016/s0092-8674(01)00213-6

PubMed ID: 16754968

Title: An improved resolution structure of the human beta common receptor involved in IL-3, IL-5 and GM-CSF signalling which gives better definition of the high-affinity binding epitope.

PubMed ID: 16754968

DOI: 10.1107/s1744309106016812

PubMed ID: 18692472

Title: The structure of the GM-CSF receptor complex reveals a distinct mode of cytokine receptor activation.

PubMed ID: 18692472

DOI: 10.1016/j.cell.2008.05.053

PubMed ID: 9410898

Title: Human pulmonary alveolar proteinosis associated with a defect in GM-CSF/IL-3/IL-5 receptor common beta chain expression.

PubMed ID: 9410898

DOI: 10.1172/jci119758

Sequence Information:

  • Length: 897
  • Mass: 97336
  • Checksum: 3398E37FDB8F393A
  • Sequence:
    • MVLAQGLLSM ALLALCWERS LAGAEETIPL QTLRCYNDYT SHITCRWADT QDAQRLVNVT 
LIRRVNEDLL EPVSCDLSDD MPWSACPHPR CVPRRCVIPC QSFVVTDVDY FSFQPDRPLG 
TRLTVTLTQH VQPPEPRDLQ ISTDQDHFLL TWSVALGSPQ SHWLSPGDLE FEVVYKRLQD 
SWEDAAILLS NTSQATLGPE HLMPSSTYVA RVRTRLAPGS RLSGRPSKWS PEVCWDSQPG 
DEAQPQNLEC FFDGAAVLSC SWEVRKEVAS SVSFGLFYKP SPDAGEEECS PVLREGLGSL 
HTRHHCQIPV PDPATHGQYI VSVQPRRAEK HIKSSVNIQM APPSLNVTKD GDSYSLRWET 
MKMRYEHIDH TFEIQYRKDT ATWKDSKTET LQNAHSMALP ALEPSTRYWA RVRVRTSRTG 
YNGIWSEWSE ARSWDTESVL PMWVLALIVI FLTIAVLLAL RFCGIYGYRL RRKWEEKIPN 
PSKSHLFQNG SAELWPPGSM SAFTSGSPPH QGPWGSRFPE LEGVFPVGFG DSEVSPLTIE 
DPKHVCDPPS GPDTTPAASD LPTEQPPSPQ PGPPAASHTP EKQASSFDFN GPYLGPPHSR 
SLPDILGQPE PPQEGGSQKS PPPGSLEYLC LPAGGQVQLV PLAQAMGPGQ AVEVERRPSQ 
GAAGSPSLES GGGPAPPALG PRVGGQDQKD SPVAIPMSSG DTEDPGVASG YVSSADLVFT 
PNSGASSVSL VPSLGLPSDQ TPSLCPGLAS GPPGAPGPVK SGFEGYVELP PIEGRSPRSP 
RNNPVPPEAK SPVLNPGERP ADVSPTSPQP EGLLVLQQVG DYCFLPGLGP GPLSLRSKPS 
SPGPGPEIKN LDQAFQVKKP PGQAVPQVPV IQLFKALKQQ DYLSLPPWEV NKPGEVC

Genular Protein ID: 1864063333

Symbol: Q6NSJ8_HUMAN

Name: N/A

UniProtKB Accession Codes:

Q6NSJ8

Database IDs:

AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CDD 1 CTD 1 ChiTaRS 1 DNASU 1 DisGeNET 1 EMBL 2 ExpressionAtlas 1 GO 2 Gene3D 1 InterPro 6 KEGG 1 MassIVE 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PIRSF 1 PROSITE 3 PeptideAtlas 1 Pfam 1 PharmGKB 1 ProteomicsDB 1 RefSeq 1 SMART 1 SMR 1 SUPFAM 1 UCSC 1 VEuPathDB 1

Citations:

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

Sequence Information:

  • Length: 889
  • Mass: 96173
  • Checksum: 1BD57B91E8CC079F
  • Sequence:
    • MVLAQGLLSM ALLALCWERS LAGAEETIPL QTLRCYNDYT SHITCRWADT QDAQRLVNVT 
LIRRVNEDLL EPVSCDLSDD MPWSACPHPR CVPRRCVIPC QSFVVTDVDY FSFQPDRPLG 
TRLTVTLTQH VQPPEPRDLQ ISTDQDHFLL TWSVALGSPQ SHWLSPGDLE FEVVYKRLQD 
SWEDAAILLS NTSQATLGPE HLMPSSTYVA RVRTRLAPGS RLSGRPSKWS PEVCWDSQPG 
DEAQPQNLEC FFDGAAVLSC SWEVRKEVAS SVSFGLFYKP SPDAGEEECS PVLREGLGSL 
HTRHHCQIPV PDPATHGQYI VSVQPRRAEK HIKSSVNIQM APPSLNVTKD GDSYSLRWET 
MKMRYEHIDH TFEIQYRKDT ATWKDSKTET LQNAHSMALP ALEPSTRYWA RVRVRTSRTG 
YNGIWSEWSE ARSWDTESVL PMWVLALIVI FLTIAVLLAL RFCGIYGYRL RRKWEEKIPN 
PSKSHLFQNG SAELWPPGSM SAFTSGSPPH QGPWGSRFPE LEGVFPVGFG DSEVSPLTIE 
DPKHVCDPPS GPDTTPAASD LPTEQPPSPQ PGPPAASHTP EKQASSFDFN GPYLGPPHSR 
SLPDILGQPE PPQEGGSQKS PPPGSLEYLC LPAGGQVQLV PLAQAMGPGQ AVEVERRPSQ 
GAAGSPSLES GGGPAPPALG PRVGGQDQKD SPVAIPMSSG DTEDPGVASG YVSSADLVFT 
PNSGASSVSL VPSLGLPSDQ TPSLCPGLAS GPPGAPGPVK SGFEGYVELP PIEGRSPRSP 
RNNPVPPEAK SPVLNPGERP ADVSPTSPQP EGLLVLQQVG DYCFLPGLGP GPLSLRSKPS 
SPGPGPEIKN LDQAFQVKKP PGQAVPQVPV IQLFKALVVS VMSVGPPVP

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.