Details for: CSF3

Gene ID: 1440

Symbol: CSF3

Ensembl ID: ENSG00000108342

Description: colony stimulating factor 3

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: ciliated cell of the bronchus (CL0002332)
    Fold Change: 9.7618
    Cell Significance Index: -9.3200
  • Cell Name: prostate gland microvascular endothelial cell (CL2000059)
    Fold Change: 9.4320
    Cell Significance Index: 67.7400
  • Cell Name: myometrial cell (CL0002366)
    Fold Change: 6.5477
    Cell Significance Index: 75.4100
  • Cell Name: vascular lymphangioblast (CL0005022)
    Fold Change: 4.9575
    Cell Significance Index: 87.6100
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: 3.5543
    Cell Significance Index: 113.8400
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: 1.9420
    Cell Significance Index: 55.6700
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: 1.3313
    Cell Significance Index: 81.6200
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.6713
    Cell Significance Index: 127.7500
  • Cell Name: fibroblast of connective tissue of nonglandular part of prostate (CL1000304)
    Fold Change: 0.5653
    Cell Significance Index: 6.1700
  • Cell Name: fibroblast of connective tissue of glandular part of prostate (CL1000305)
    Fold Change: 0.5188
    Cell Significance Index: 5.7300
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: 0.4907
    Cell Significance Index: 29.4600
  • Cell Name: hematopoietic stem cell (CL0000037)
    Fold Change: 0.3691
    Cell Significance Index: 6.3100
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 0.2740
    Cell Significance Index: 29.8000
  • Cell Name: epithelial cell of lacrimal sac (CL1000436)
    Fold Change: 0.2585
    Cell Significance Index: 1.8600
  • Cell Name: pulmonary capillary endothelial cell (CL4028001)
    Fold Change: 0.2454
    Cell Significance Index: 3.3600
  • Cell Name: type I muscle cell (CL0002211)
    Fold Change: 0.2184
    Cell Significance Index: 5.3300
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: 0.2050
    Cell Significance Index: 4.3700
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 0.1441
    Cell Significance Index: 9.9700
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.1323
    Cell Significance Index: 119.4400
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.1272
    Cell Significance Index: 12.5900
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.1076
    Cell Significance Index: 17.5000
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: 0.0610
    Cell Significance Index: 38.0900
  • Cell Name: endothelial cell of venule (CL1000414)
    Fold Change: 0.0452
    Cell Significance Index: 0.5100
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 0.0446
    Cell Significance Index: 24.3500
  • Cell Name: odontoblast (CL0000060)
    Fold Change: 0.0356
    Cell Significance Index: 4.5600
  • Cell Name: skeletal muscle satellite stem cell (CL0008011)
    Fold Change: 0.0115
    Cell Significance Index: 0.1200
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: 0.0059
    Cell Significance Index: 1.0100
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: 0.0024
    Cell Significance Index: 1.8300
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 0.0014
    Cell Significance Index: 0.0500
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0027
    Cell Significance Index: -2.0100
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0039
    Cell Significance Index: -2.1800
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: -0.0040
    Cell Significance Index: -0.1000
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: -0.0040
    Cell Significance Index: -7.5200
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: -0.0045
    Cell Significance Index: -0.1300
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.0047
    Cell Significance Index: -0.9900
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: -0.0074
    Cell Significance Index: -0.1600
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: -0.0081
    Cell Significance Index: -1.0000
  • Cell Name: fallopian tube secretory epithelial cell (CL4030006)
    Fold Change: -0.0090
    Cell Significance Index: -0.1400
  • Cell Name: lactocyte (CL0002325)
    Fold Change: -0.0122
    Cell Significance Index: -1.5800
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.0127
    Cell Significance Index: -1.4600
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: -0.0143
    Cell Significance Index: -0.6500
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: -0.0171
    Cell Significance Index: -10.8500
  • Cell Name: fibro/adipogenic progenitor cell (CL0009099)
    Fold Change: -0.0194
    Cell Significance Index: -0.9800
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0227
    Cell Significance Index: -10.2900
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: -0.0258
    Cell Significance Index: -4.6500
  • Cell Name: BEST4+ enteroycte (CL4030026)
    Fold Change: -0.0338
    Cell Significance Index: -0.5100
  • Cell Name: pancreatic endocrine cell (CL0008024)
    Fold Change: -0.0372
    Cell Significance Index: -4.2500
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.0389
    Cell Significance Index: -11.1900
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: -0.0395
    Cell Significance Index: -7.9200
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: -0.0416
    Cell Significance Index: -8.2600
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: -0.0503
    Cell Significance Index: -6.9100
  • Cell Name: transit amplifying cell of small intestine (CL0009012)
    Fold Change: -0.0506
    Cell Significance Index: -1.0500
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.0534
    Cell Significance Index: -6.2200
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: -0.0695
    Cell Significance Index: -3.2700
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.0706
    Cell Significance Index: -10.2600
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.0762
    Cell Significance Index: -7.9300
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: -0.0813
    Cell Significance Index: -6.0600
  • Cell Name: keratinocyte (CL0000312)
    Fold Change: -0.0857
    Cell Significance Index: -2.1400
  • Cell Name: type II muscle cell (CL0002212)
    Fold Change: -0.0917
    Cell Significance Index: -1.4800
  • Cell Name: stratified epithelial cell (CL0000079)
    Fold Change: -0.0948
    Cell Significance Index: -3.4800
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: -0.1008
    Cell Significance Index: -2.5900
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: -0.1067
    Cell Significance Index: -5.5600
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.1076
    Cell Significance Index: -10.9900
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: -0.1112
    Cell Significance Index: -8.5300
  • Cell Name: hepatoblast (CL0005026)
    Fold Change: -0.1142
    Cell Significance Index: -1.9200
  • Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
    Fold Change: -0.1180
    Cell Significance Index: -1.6900
  • Cell Name: choroid plexus epithelial cell (CL0000706)
    Fold Change: -0.1210
    Cell Significance Index: -1.4400
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: -0.1219
    Cell Significance Index: -3.4100
  • Cell Name: endocrine cell (CL0000163)
    Fold Change: -0.1274
    Cell Significance Index: -1.5400
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: -0.1278
    Cell Significance Index: -8.5900
  • Cell Name: retinal blood vessel endothelial cell (CL0002585)
    Fold Change: -0.1378
    Cell Significance Index: -1.7800
  • Cell Name: eukaryotic cell (CL0000255)
    Fold Change: -0.1410
    Cell Significance Index: -6.1300
  • Cell Name: fibroblast of dermis (CL0002551)
    Fold Change: -0.1624
    Cell Significance Index: -3.4000
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: -0.1663
    Cell Significance Index: -9.3300
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: -0.1672
    Cell Significance Index: -4.5500
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: -0.1715
    Cell Significance Index: -8.9100
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: -0.1744
    Cell Significance Index: -10.7200
  • Cell Name: decidual cell (CL2000002)
    Fold Change: -0.1776
    Cell Significance Index: -2.8500
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: -0.1777
    Cell Significance Index: -9.3300
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: -0.1810
    Cell Significance Index: -8.4400
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: -0.1838
    Cell Significance Index: -11.8600
  • Cell Name: monocyte-derived dendritic cell (CL0011031)
    Fold Change: -0.1880
    Cell Significance Index: -3.2300
  • Cell Name: peg cell (CL4033014)
    Fold Change: -0.1991
    Cell Significance Index: -4.6000
  • Cell Name: progenitor cell (CL0011026)
    Fold Change: -0.2255
    Cell Significance Index: -2.4000
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: -0.2284
    Cell Significance Index: -8.0000
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: -0.2322
    Cell Significance Index: -6.2000
  • Cell Name: erythrocyte (CL0000232)
    Fold Change: -0.2331
    Cell Significance Index: -5.9400
  • Cell Name: megakaryocyte-erythroid progenitor cell (CL0000050)
    Fold Change: -0.2399
    Cell Significance Index: -3.2900
  • Cell Name: vasa recta ascending limb cell (CL1001131)
    Fold Change: -0.2423
    Cell Significance Index: -1.5800
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -0.2428
    Cell Significance Index: -7.9500
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -0.2509
    Cell Significance Index: -7.9900
  • Cell Name: cerebral cortex endothelial cell (CL1001602)
    Fold Change: -0.2688
    Cell Significance Index: -5.4700
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: -0.2713
    Cell Significance Index: -7.2700
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: -0.2841
    Cell Significance Index: -7.6000
  • Cell Name: hippocampal pyramidal neuron (CL1001571)
    Fold Change: -0.3010
    Cell Significance Index: -8.5900
  • Cell Name: skeletal muscle myoblast (CL0000515)
    Fold Change: -0.3127
    Cell Significance Index: -3.4000
  • Cell Name: prostate stromal cell (CL0002622)
    Fold Change: -0.3150
    Cell Significance Index: -1.5000
  • Cell Name: corneal epithelial cell (CL0000575)
    Fold Change: -0.3175
    Cell Significance Index: -4.5200
  • Cell Name: T-helper 17 cell (CL0000899)
    Fold Change: -0.3197
    Cell Significance Index: -2.4400
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: -0.3229
    Cell Significance Index: -8.4900

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics** CSF3 is a member of the interleukin-3 (IL-3) family of cytokines, which are essential for the development and differentiation of various cell types, including hematopoietic cells, immune cells, and tissue cells. It is produced by various cell types, including stromal cells, endothelial cells, and fibroblasts, and is secreted into the extracellular space. CSF3 is a dimeric glycoprotein composed of two alpha subunits, each with a molecular weight of approximately 25 kDa. **Pathways and Functions** CSF3 exerts its effects through the binding of its receptor, G-CSF receptor (G-CSFR), which is expressed on the surface of various cell types, including hematopoietic cells, immune cells, and tissue cells. The binding of CSF3 to its receptor triggers a signaling cascade that involves the activation of several downstream pathways, including: 1. **Phosphatidylinositol 3-kinase/protein kinase B (PI3K/Akt) pathway**: This pathway is involved in cell survival, proliferation, and differentiation. 2. **Ras/Raf/MAPK pathway**: This pathway is involved in cell proliferation, differentiation, and apoptosis. 3. **NF-κB pathway**: This pathway is involved in the regulation of immune responses, inflammation, and cell survival. CSF3 plays a critical role in various cellular processes, including: 1. **Hematopoiesis**: CSF3 stimulates the proliferation, differentiation, and maturation of hematopoietic cells, including granulocytes, monocytes, and stem cells. 2. **Immune response**: CSF3 enhances the production of immune cells, such as neutrophils, monocytes, and lymphocytes, and regulates the activity of immune cells. 3. **Tissue repair**: CSF3 promotes the proliferation and differentiation of tissue cells, including fibroblasts, endothelial cells, and epithelial cells. **Clinical Significance** CSF3 has been used therapeutically to treat various conditions, including: 1. **Neutropenia**: CSF3 has been used to stimulate the production of neutrophils in patients with neutropenia, a condition characterized by an abnormally low count of neutrophils. 2. **Leukemia**: CSF3 has been used to stimulate the production of granulocytes in patients with leukemia, a type of cancer that affects blood and bone marrow. 3. **Inflammatory disorders**: CSF3 has been used to treat inflammatory disorders, such as rheumatoid arthritis and multiple sclerosis, by enhancing the production of anti-inflammatory immune cells. 4. **Organ transplantation**: CSF3 has been used to stimulate the proliferation and differentiation of tissue cells, including endothelial cells and fibroblasts, to promote wound healing and tissue repair. In conclusion, CSF3 is a critical cytokine that plays a central role in regulating hematopoiesis, immune response, and tissue repair. Its dysregulation has been implicated in various diseases, and its therapeutic potential has been explored in various clinical settings. As an expert immunologist, I believe that further research on CSF3 will provide valuable insights into the regulation of immune responses and tissue repair, and will lead to the development of novel therapeutic strategies for the treatment of various diseases.

Genular Protein ID: 4015001817

Symbol: CSF3_HUMAN

Name: Granulocyte colony-stimulating factor

UniProtKB Accession Codes:

P09919 A8MXR7

Database IDs:

AGR 1 Allergome 1 AlphaFoldDB 1 Antibodypedia 1 BMRB 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 3 CTD 1 CarbonylDB 1 ChiTaRS 1 DIP 1 DMDM 1 DNASU 1 DisGeNET 1 EMBL 8 Ensembl 3 EvolutionaryTrace 1 ExpressionAtlas 1 GO 22 Gene3D 1 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyCosmos 1 GlyGen 1 HGNC 1 HPA 1 InParanoid 1 IntAct 1 InterPro 4 KEGG 1 MANE-Select 1 MIM 1 MassIVE 1 MetOSite 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PDB 7 PDBsum 7 PIR 2 PIRSF 1 PRINTS 1 PRO 1 PROSITE 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 1 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 3 RNAct 1 Reactome 4 RefSeq 4 SIGNOR 1 SMART 1 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 neXtProt 1

Citations:

PubMed ID: 3484805

Title: Molecular cloning and expression of cDNA for human granulocyte colony-stimulating factor.

PubMed ID: 3484805

DOI: 10.1038/319415a0

PubMed ID: 2423327

Title: The chromosomal gene structure and two mRNAs for human granulocyte colony-stimulating factor.

PubMed ID: 2423327

DOI: 10.1002/j.1460-2075.1986.tb04249.x

PubMed ID: 3494801

Title: Expression of granulocyte colony-stimulating factor by human cell lines.

PubMed ID: 3494801

DOI: 10.1002/jlb.41.4.302

PubMed ID: 15028279

Title: PCR isolation and cloning of novel splice variant mRNAs from known drug target genes.

PubMed ID: 15028279

DOI: 10.1016/j.ygeno.2003.09.023

PubMed ID: 16625196

Title: DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage.

PubMed ID: 16625196

DOI: 10.1038/nature04689

PubMed ID: 2420009

Title: Recombinant human granulocyte colony-stimulating factor: effects on normal and leukemic myeloid cells.

PubMed ID: 2420009

DOI: 10.1126/science.2420009

PubMed ID: 8554326

Title: Extracellular domain of granulocyte-colony stimulating factor receptor. Interaction with its ligand and identification of a domain in close proximity of ligand-binding region.

PubMed ID: 8554326

DOI: 10.1006/abbi.1995.0047

PubMed ID: 7685769

Title: Glycosidase digestion, electrophoresis and chromatographic analysis of recombinant human granulocyte colony-stimulating factor glycoforms produced in Chinese hamster ovary cells.

PubMed ID: 7685769

DOI: 10.1016/0021-9673(93)83098-d

PubMed ID: 1281794

Title: Secondary structure of human granulocyte colony-stimulating factor derived from NMR spectroscopy.

PubMed ID: 1281794

DOI: 10.1016/0014-5793(92)81521-m

PubMed ID: 7518249

Title: Structure and dynamics of the human granulocyte colony-stimulating factor determined by NMR spectroscopy. Loop mobility in a four-helix-bundle protein.

PubMed ID: 7518249

DOI: 10.1021/bi00194a009

PubMed ID: 7685117

Title: The structure of granulocyte-colony-stimulating factor and its relationship to other growth factors.

PubMed ID: 7685117

DOI: 10.1073/pnas.90.11.5167

PubMed ID: 10537111

Title: Atomic structure of the GCSF-receptor complex showing a new cytokine-receptor recognition scheme.

PubMed ID: 10537111

DOI: 10.1038/44394

PubMed ID: 16492764

Title: Homodimeric cross-over structure of the human granulocyte colony-stimulating factor (GCSF) receptor signaling complex.

PubMed ID: 16492764

DOI: 10.1073/pnas.0511264103

Sequence Information:

  • Length: 207
  • Mass: 22293
  • Checksum: 421F635ECC776996
  • Sequence:
    • MAGPATQSPM KLMALQLLLW HSALWTVQEA TPLGPASSLP QSFLLKCLEQ VRKIQGDGAA 
LQEKLVSECA TYKLCHPEEL VLLGHSLGIP WAPLSSCPSQ ALQLAGCLSQ LHSGLFLYQG 
LLQALEGISP ELGPTLDTLQ LDVADFATTI WQQMEELGMA PALQPTQGAM PAFASAFQRR 
AGGVLVASHL QSFLEVSYRV LRHLAQP

Genular Protein ID: 1276945798

Symbol: Q6FH65_HUMAN

Name: N/A

UniProtKB Accession Codes:

Q6FH65

Database IDs:

ARBA 8 Allergome 1 AlphaFoldDB 1 Antibodypedia 1 BioGRID-ORCS 1 CTD 1 ChiTaRS 1 DNASU 1 DisGeNET 1 EMBL 6 ExpressionAtlas 1 GO 9 Gene3D 1 InterPro 4 NCBI Taxonomy 1 OMA 1 OrthoDB 1 PANTHER 2 PIRSF 1 PIRSR 1 PRINTS 1 PROSITE 1 Pfam 1 PharmGKB 1 RefSeq 1 SAM 1 SMART 1 SMR 1 SUPFAM 1 UCSC 1 VEuPathDB 1

Citations:

PubMed ID: 11181995

Title: The sequence of the human genome.

PubMed ID: 11181995

DOI: 10.1126/science.1058040

Sequence Information:

  • Length: 204
  • Mass: 21978
  • Checksum: 5F07C52F13D6A6D3
  • Sequence:
    • MAGPATQSPM KLMALQLLLW HSALWTVQEA TPLGPASSLP QSFLLKCLEQ VRKIQGDGAA 
LQEKLCATYK LCHPEELVLL GHSLGIPWAP LSSCPSQALQ LAGCLSQLHS GLFLYQGLLQ 
ALEGISPELG PTLDTLQLDV ADFATTIWQQ MEELGMAPAL QPTQGAMPAF ASAFQRRAGG 
VLVASHLQSF LEVSYRVLRH LAQP

Genular Protein ID: 142117710

Symbol: Q8N4W3_HUMAN

Name: N/A

UniProtKB Accession Codes:

Q8N4W3

Database IDs:

ARBA 8 Allergome 1 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CTD 1 ChiTaRS 1 DNASU 1 DisGeNET 1 EMBL 7 Ensembl 2 GO 4 Gene3D 1 GeneTree 1 HGNC 1 IntAct 1 InterPro 4 KEGG 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PIRSF 1 PIRSR 1 PRINTS 1 PROSITE 1 PeptideAtlas 1 Pfam 1 PharmGKB 1 Proteomes 2 ProteomicsDB 2 RefSeq 4 SAM 1 SMART 1 SUPFAM 1 UCSC 1 VEuPathDB 1

Citations:

PubMed ID: 11237011

Title: Initial sequencing and analysis of the human genome.

PubMed ID: 11237011

DOI: 10.1038/35057062

PubMed ID: 11181995

Title: The sequence of the human genome.

PubMed ID: 11181995

DOI: 10.1126/science.1058040

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 15496913

Title: Finishing the euchromatic sequence of the human genome.

PubMed ID: 15496913

DOI: 10.1038/nature03001

PubMed ID: 16625196

Title: DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage.

PubMed ID: 16625196

DOI: 10.1038/nature04689

Sequence Information:

  • Length: 200
  • Mass: 21543
  • Checksum: 8648AA55B329A96C
  • Sequence:
    • MSPEPALSPA LQLLLWHSAL WTVQEATPLG PASSLPQSFL LKCLEQVRKI QGDGAALQEK 
LCATYKLCHP EELVLLGHSL GIPWAPLSSC PSQALQLAGC LSQLHSGLFL YQGLLQALEG 
ISPELGPTLD TLQLDVADFA TTIWQQMEEL GMAPALQPTQ GAMPAFASAF QRRAGGVLVA 
SHLQSFLEVS YRVLRHLAQP

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.