Gabrb2 | ENSMUSG00000007653 | NCBI 14401

Details for: Gabrb2

Gene ID: 14401

Symbol: Gabrb2

Ensembl ID: ENSMUSG00000007653

Description: gamma-aminobutyric acid type A receptor subunit beta 2

Associated with

Gaba receptor activation
(R-MMU-977443)
Neuronal system
(R-MMU-112316)
Neurotransmitter receptors and postsynaptic signal transmission
(R-MMU-112314)
Transmission across chemical synapses
(R-MMU-112315)
Cellular response to histamine
(GO:0071420)
Chemical synaptic transmission
(GO:0007268)
Chemical synaptic transmission, postsynaptic
(GO:0099565)
Chloride channel activity
(GO:0005254)
Chloride channel complex
(GO:0034707)
Chloride transmembrane transport
(GO:1902476)
Chloride transport
(GO:0006821)
Cochlea development
(GO:0090102)
Cytoplasmic vesicle
(GO:0031410)
Extracellular ligand-gated monoatomic ion channel activity
(GO:0005230)
Gaba-a receptor activity
(GO:0004890)
Gaba-a receptor complex
(GO:1902711)
Gaba-ergic synapse
(GO:0098982)
Gaba-gated chloride ion channel activity
(GO:0022851)
Gaba receptor activity
(GO:0016917)
Gaba receptor complex
(GO:1902710)
Gamma-aminobutyric acid signaling pathway
(GO:0007214)
Glutamatergic synapse
(GO:0098978)
Inhibitory extracellular ligand-gated monoatomic ion channel activity
(GO:0005237)
Inhibitory synapse assembly
(GO:1904862)
Inner ear receptor cell development
(GO:0060119)
Innervation
(GO:0060384)
Ligand-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential
(GO:0099507)
Membrane
(GO:0016020)
Monoatomic ion channel activity
(GO:0005216)
Monoatomic ion transmembrane transport
(GO:0034220)
Monoatomic ion transport
(GO:0006811)
Nervous system process
(GO:0050877)
Neuron development
(GO:0048666)
Neuron projection
(GO:0043005)
Neurotransmitter receptor activity
(GO:0030594)
Plasma membrane
(GO:0005886)
Postsynaptic membrane
(GO:0045211)
Postsynaptic specialization membrane
(GO:0099634)
Presynaptic active zone membrane
(GO:0048787)
Protein binding
(GO:0005515)
Regulation of membrane potential
(GO:0042391)
Regulation of postsynaptic membrane potential
(GO:0060078)
Synapse
(GO:0045202)
Synaptic transmission, gabaergic
(GO:0051932)
Transmembrane signaling receptor activity
(GO:0004888)
Transmembrane transporter complex
(GO:1902495)
Transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential
(GO:1904315)

Other Information

Proteins

Gamma-aminobutyric acid receptor subunit beta-2

Genular Protein ID: 2446137941

Symbol: GBRB2_MOUSE

Name: Gamma-aminobutyric acid receptor subunit beta-2

UniProtKB Accession Codes:

P63137 A6H6R7 D1LYT3 P15432

Database IDs:

Citations:

PubMed ID: 7893750

Title: GABAA receptor beta 1, beta 2, and beta 3 subunits: comparisons in DBA/2J and C57BL/6J mice.

PubMed ID: 7893750

DOI: 10.1016/0167-4781(95)00009-6

PubMed ID: 19763268

Title: Alternative-splicing in the exon-10 region of GABA(A) receptor beta(2) subunit gene: relationships between novel isoforms and psychotic disorders.

PubMed ID: 19763268

DOI: 10.1371/journal.pone.0006977

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 19468303

Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.

PubMed ID: 19468303

DOI: 10.1371/journal.pbio.1000112

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 18034455

Title: Large-scale identification and evolution indexing of tyrosine phosphorylation sites from murine brain.

PubMed ID: 18034455

DOI: 10.1021/pr0701254

PubMed ID: 20400944

Title: Native GABA(B) receptors are heteromultimers with a family of auxiliary subunits.

PubMed ID: 20400944

DOI: 10.1038/nature08964

PubMed ID: 27129275

Title: Gamma-aminobutyric acid type A (GABAA) receptor subunits play a direct structural role in synaptic contact formation via their N-terminal extracellular domains.

PubMed ID: 27129275

DOI: 10.1074/jbc.m116.714790

Sequence Information:

Length: 512
Mass: 59197
Checksum: 41AC9154A438E4FF
Sequence:

MWRVRKRGYF GIWSFPLIIA AVCAQSVNDP SNMSLVKETV DRLLKGYDIR LRPDFGGPPV 
AVGMNIDIAS IDMVSEVNMD YTLTMYFQQA WRDKRLSYNV IPLNLTLDNR VADQLWVPDT 
YFLNDKKSFV HGVTVKNRMI RLHPDGTVLY GLRITTTAAC MMDLRRYPLD EQNCTLEIES 
YGYTTDDIEF YWRGDDNAVT GVTKIELPQF SIVDYKLITK KVVFSTGSYP RLSLSFKLKR 
NIGYFILQTY MPSILITILS WVSFWINYDA SAARVALGIT TVLTMTTINT HLRETLPKIP 
YVKAIDMYLM GCFVFVFMAL LEYALVNYIF FGRGPQRQKK AAEKAANANN EKMRLDVNKM 
FYKDIKQNGT QYRSLWDPTG DLSPTRRTTN YDFSLYTMDP HENILLSTLE IKNEMATSEA 
VMGLGDPRST MLAYDASSIQ YRKAGLPRHS FGRNALERHV AQKKSRLRRR ASQLKITIPD 
LTDVNAIDRW SRIFFPVVFS FFNIVYWLYY VN

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Gabrb2

Associated with

Other Information

GABAA receptor beta 1, beta 2, and beta 3 subunits: comparisons in DBA/2J and C57BL/6J mice. PubMed ID: 7893750

Alternative-splicing in the exon-10 region of GABA(A) receptor beta(2) subunit gene: relationships between novel isoforms and psychotic disorders. PubMed ID: 19763268

The transcriptional landscape of the mammalian genome. PubMed ID: 16141072

Lineage-specific biology revealed by a finished genome assembly of the mouse. PubMed ID: 19468303

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Large-scale identification and evolution indexing of tyrosine phosphorylation sites from murine brain. PubMed ID: 18034455

Native GABA(B) receptors are heteromultimers with a family of auxiliary subunits. PubMed ID: 20400944

Gamma-aminobutyric acid type A (GABAA) receptor subunits play a direct structural role in synaptic contact formation via their N-terminal extracellular domains. PubMed ID: 27129275