Details for: CSF3R
Associated with
Other Information
Genular Protein ID: 1665202947
Symbol: CSF3R_HUMAN
Name: Granulocyte colony-stimulating factor receptor
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 2147944
Title: Expression cloning of a human granulocyte colony-stimulating factor receptor: a structural mosaic of hematopoietin receptor, immunoglobulin, and fibronectin domains.
PubMed ID: 2147944
PubMed ID: 1701053
Title: Three different mRNAs encoding human granulocyte colony-stimulating factor receptor.
PubMed ID: 1701053
PubMed ID: 1530796
Title: Chromosomal gene organization of the human granulocyte colony-stimulating factor receptor.
PubMed ID: 1530796
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 8554326
Title: Extracellular domain of granulocyte-colony stimulating factor receptor. Interaction with its ligand and identification of a domain in close proximity of ligand-binding region.
PubMed ID: 8554326
PubMed ID: 1717255
Title: Functional domains of the granulocyte colony-stimulating factor receptor.
PubMed ID: 1717255
PubMed ID: 7514305
Title: Identification of a nonsense mutation in the granulocyte-colony-stimulating factor receptor in severe congenital neutropenia.
PubMed ID: 7514305
PubMed ID: 17127321
Title: Granulocyte colony-stimulating factor and its receptor in normal myeloid cell development, leukemia and related blood cell disorders.
PubMed ID: 17127321
DOI: 10.2741/2103
PubMed ID: 19120359
Title: Clinical implications of ELA2-, HAX1-, and G-CSF-receptor (CSF3R) mutations in severe congenital neutropenia.
PubMed ID: 19120359
PubMed ID: 9187659
Title: Solution structure of an extracellular domain containing the WSxWS motif of the granulocyte colony-stimulating factor receptor and its interaction with ligand.
PubMed ID: 9187659
DOI: 10.1038/nsb0697-498
PubMed ID: 9368043
Title: Identification of a ligand-binding site on the granulocyte colony-stimulating factor receptor by molecular modeling and mutagenesis.
PubMed ID: 9368043
PubMed ID: 16492764
Title: Homodimeric cross-over structure of the human granulocyte colony-stimulating factor (GCSF) receptor signaling complex.
PubMed ID: 16492764
PubMed ID: 10449521
Title: Novel point mutation in the extracellular domain of the granulocyte colony-stimulating factor (G-CSF) receptor in a case of severe congenital neutropenia hyporesponsive to G-CSF treatment.
PubMed ID: 10449521
PubMed ID: 19620628
Title: An activating mutation in the CSF3R gene induces a hereditary chronic neutrophilia.
PubMed ID: 19620628
DOI: 10.1084/jem.20090693
PubMed ID: 24753537
Title: Inherited biallelic CSF3R mutations in severe congenital neutropenia.
PubMed ID: 24753537
PubMed ID: 26324699
Title: GM-CSF stimulates granulopoiesis in a congenital neutropenia patient with loss-of-function biallelic heterozygous CSF3R mutations.
PubMed ID: 26324699
Sequence Information:
- Length: 836
- Mass: 92156
- Checksum: 3531ADDC979D4BC3
- Sequence:
MARLGNCSLT WAALIILLLP GSLEECGHIS VSAPIVHLGD PITASCIIKQ NCSHLDPEPQ ILWRLGAELQ PGGRQQRLSD GTQESIITLP HLNHTQAFLS CCLNWGNSLQ ILDQVELRAG YPPAIPHNLS CLMNLTTSSL ICQWEPGPET HLPTSFTLKS FKSRGNCQTQ GDSILDCVPK DGQSHCCIPR KHLLLYQNMG IWVQAENALG TSMSPQLCLD PMDVVKLEPP MLRTMDPSPE AAPPQAGCLQ LCWEPWQPGL HINQKCELRH KPQRGEASWA LVGPLPLEAL QYELCGLLPA TAYTLQIRCI RWPLPGHWSD WSPSLELRTT ERAPTVRLDT WWRQRQLDPR TVQLFWKPVP LEEDSGRIQG YVVSWRPSGQ AGAILPLCNT TELSCTFHLP SEAQEVALVA YNSAGTSRPT PVVFSESRGP ALTRLHAMAR DPHSLWVGWE PPNPWPQGYV IEWGLGPPSA SNSNKTWRME QNGRATGFLL KENIRPFQLY EIIVTPLYQD TMGPSQHVYA YSQEMAPSHA PELHLKHIGK TWAQLEWVPE PPELGKSPLT HYTIFWTNAQ NQSFSAILNA SSRGFVLHGL EPASLYHIHL MAASQAGATN STVLTLMTLT PEGSELHIIL GLFGLLLLLT CLCGTAWLCC SPNRKNPLWP SVPDPAHSSL GSWVPTIMEE DAFQLPGLGT PPITKLTVLE EDEKKPVPWE SHNSSETCGL PTLVQTYVLQ GDPRAVSTQP QSQSGTSDQV LYGQLLGSPT SPGPGHYLRC DSTQPLLAGL TPSPKSYENL WFQASPLGTL VTPAPSQEDD CVFGPLLNFP LLQGIRVHGM EALGSF
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.