Genular: Defining Cellular Identity and Function

Details for: Slc6a13

Gene ID: 14412

Symbol: Slc6a13

Ensembl ID: ENSMUSG00000030108

Description: solute carrier family 6 (neurotransmitter transporter, GABA), member 13

Associated with

Gaba synthesis, release, reuptake and degradation
(R-MMU-888590)
Na+/cl- dependent neurotransmitter transporters
(R-MMU-442660)
Neuronal system
(R-MMU-112316)
Neurotransmitter release cycle
(R-MMU-112310)
Reuptake of gaba
(R-MMU-888593)
Slc-mediated transmembrane transport
(R-MMU-425407)
Transmission across chemical synapses
(R-MMU-112315)
Transport of bile salts and organic acids, metal ions and amine compounds
(R-MMU-425366)
Transport of small molecules
(R-MMU-382551)
Amino acid:sodium symporter activity
(GO:0005283)
Amino acid binding
(GO:0016597)
Amino acid import across plasma membrane
(GO:0089718)
Amino acid transmembrane transporter activity
(GO:0015171)
Amino acid transport
(GO:0006865)
Basolateral plasma membrane
(GO:0016323)
Cell projection
(GO:0042995)
Creatine transmembrane transport
(GO:0015881)
Creatine transmembrane transporter activity
(GO:0005308)
Gamma-aminobutyric acid:sodium:chloride symporter activity
(GO:0005332)
Gamma-aminobutyric acid import
(GO:0051939)
Gamma-aminobutyric acid transmembrane transporter activity
(GO:0015185)
Membrane
(GO:0016020)
Monocarboxylic acid transmembrane transporter activity
(GO:0008028)
Monocarboxylic acid transport
(GO:0015718)
Neurotransmitter transport
(GO:0006836)
Nitrogen compound transport
(GO:0071705)
Plasma membrane
(GO:0005886)
Sodium ion transmembrane transport
(GO:0035725)
Symporter activity
(GO:0015293)
Taurine:sodium symporter activity
(GO:0005369)
Taurine transmembrane transporter activity
(GO:0005368)
Taurine transport
(GO:0015734)

Other Information

Proteins

Solute carrier family 6 member 13

Genular Protein ID: 1853389622

Symbol: S6A13_MOUSE

Name: Solute carrier family 6 member 13

UniProtKB Accession Codes:

P31649

Database IDs:

Citations:

PubMed ID: 8420981

Title: Molecular characterization of four pharmacologically distinct gamma-aminobutyric acid transporters in mouse brain.

PubMed ID: 8420981

DOI: 10.1016/s0021-9258(18)53968-5

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 17242355

Title: Large-scale phosphorylation analysis of mouse liver.

PubMed ID: 17242355

DOI: 10.1073/pnas.0609836104

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

PubMed ID: 22896705

Title: Deletion of the gamma-aminobutyric acid transporter 2 (GAT2 and SLC6A13) gene in mice leads to changes in liver and brain taurine contents.

PubMed ID: 22896705

DOI: 10.1074/jbc.m112.368175

PubMed ID: 30270321

Title: Hypotaurine Is a Substrate of GABA Transporter Family Members GAT2/Slc6a13 and TAUT/Slc6a6.

PubMed ID: 30270321

DOI: 10.1248/bpb.b18-00168

Sequence Information:

Length: 602
Mass: 68285
Checksum: 372FE77F3126ABEA
Sequence:

MENRASGTTS NGETKPVCPA MEKVEEDGTL EREHWNNKME FVLSVAGEII GLGNVWRFPY 
LCYKNGGGAF FIPYLIFLFT CGIPVFFLET ALGQYTNQGG ITAWRRICPI FEGIGYASQM 
IVSLLNVYYI VVLAWALFYL FSSFTTDLPW GSCSHEWNTE NCVEFQKAND SMNVTSENAT 
SPVIEFWERR VLKLSDGIQH LGSLRWELVL CLLLAWIICY FCIWKGVKST GKVVYFTATF 
PYLMLVVLLI RGVTLPGAAQ GIQFYLYPNI TRLWDPQVWM DAGTQIFFSF AICLGCLTAL 
GSYNKYHNNC YRDCIALCIL NSSTSFMAGF AIFSILGFMS QEQGVPISEV AESGPGLAFI 
AYPRAVVMLP FSPLWACCFF FMVVLLGLDS QFVCVESLVT ALVDMYPRVF RKKNRREVLI 
LIVSVISFFI GLIMLTEGGM YVFQLFDYYA ASGMCLLFVA IFESLCVAWV YGAGRFYDNI 
EDMIGYKPWP LIKYCWLFFT PAVCLATFLF SLIKYTPLTY NKKYTYPWWG DALGWLLALS 
SMICIPAWSI YKLRTLKGPL RERLRQLVCP AEDLPQKNQP EPTAPATPMT SLLRLTELES 
NC

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Slc6a13

Associated with

Other Information

Molecular characterization of four pharmacologically distinct gamma-aminobutyric acid transporters in mouse brain. PubMed ID: 8420981

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Large-scale phosphorylation analysis of mouse liver. PubMed ID: 17242355

A tissue-specific atlas of mouse protein phosphorylation and expression. PubMed ID: 21183079

Deletion of the gamma-aminobutyric acid transporter 2 (GAT2 and SLC6A13) gene in mice leads to changes in liver and brain taurine contents. PubMed ID: 22896705