Genular: Defining Cellular Identity and Function

Details for: Gamt

Gene ID: 14431

Symbol: Gamt

Ensembl ID: ENSMUSG00000020150

Description: guanidinoacetate methyltransferase

Associated with

Creatine metabolism
(R-MMU-71288)
Metabolism
(R-MMU-1430728)
Metabolism of amino acids and derivatives
(R-MMU-71291)
Animal organ morphogenesis
(GO:0009887)
Cell projection
(GO:0042995)
Creatine biosynthetic process
(GO:0006601)
Cytoplasm
(GO:0005737)
Cytosol
(GO:0005829)
Guanidinoacetate n-methyltransferase activity
(GO:0030731)
Identical protein binding
(GO:0042802)
Methylation
(GO:0032259)
Methyltransferase activity
(GO:0008168)
Nucleus
(GO:0005634)
Regulation of multicellular organism growth
(GO:0040014)
S-adenosylhomocysteine metabolic process
(GO:0046498)
S-adenosylmethionine-dependent methyltransferase activity
(GO:0008757)
S-adenosylmethionine metabolic process
(GO:0046500)
Spermatogenesis
(GO:0007283)
Transferase activity
(GO:0016740)

Other Information

Proteins

Guanidinoacetate N-methyltransferase

Genular Protein ID: 2489042814

Symbol: GAMT_MOUSE

Name: Guanidinoacetate N-methyltransferase

UniProtKB Accession Codes:

O35969 Q3TZ58 Q3US90

Database IDs:

Citations:

PubMed ID: 9325156

Title: The human guanidinoacetate methyltransferase (GAMT) gene maps to a syntenic region on 19p13.3, homologous to band C of mouse chromosome 10, but GAMT is not mutated in jittery mice.

PubMed ID: 9325156

DOI: 10.1006/bbrc.1997.9992

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 8312439

Title: Guanidinoacetate methyltransferase in the mouse: extensive expression in Sertoli cells of testis and in microvilli of caput epididymis.

PubMed ID: 8312439

DOI: 10.1095/biolreprod50.1.152

PubMed ID: 15245487

Title: Distinct cellular expressions of creatine synthetic enzyme GAMT and creatine kinases uCK-Mi and CK-B suggest a novel neuron-glial relationship for brain energy homeostasis.

PubMed ID: 15245487

DOI: 10.1111/j.1460-9568.2004.03478.x

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

Sequence Information:

Length: 236
Mass: 26336
Checksum: 3D982DE5D51DF5CD
Sequence:

MSSSAASPLF APGEDCGPAW RAAPAAYDAS DTHLQILGKP VMERWETPYM HALAAAAASR 
GGRVLEVGFG MAIAASRVQQ APIEEHWIIE CNDGVFQRLQ DWALRQPHKV VPLKGLWEEV 
APTLPDGHFD GILYDTYPLS EEAWHTHQFN FIKNHAFRLL KTGGVLTYCN LTSWGELMKS 
KYTDITTMFE ETQVPALQEA GFLKENICTE VMALVPPADC RYYAFPQMIT PLVTKH

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Gamt

Associated with

Other Information

The human guanidinoacetate methyltransferase (GAMT) gene maps to a syntenic region on 19p13.3, homologous to band C of mouse chromosome 10, but GAMT is not mutated in jittery mice. PubMed ID: 9325156

The transcriptional landscape of the mammalian genome. PubMed ID: 16141072

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Guanidinoacetate methyltransferase in the mouse: extensive expression in Sertoli cells of testis and in microvilli of caput epididymis. PubMed ID: 8312439

Distinct cellular expressions of creatine synthetic enzyme GAMT and creatine kinases uCK-Mi and CK-B suggest a novel neuron-glial relationship for brain energy homeostasis. PubMed ID: 15245487