Genular: Defining Cellular Identity and Function

Details for: Gart

Gene ID: 14450

Symbol: Gart

Ensembl ID: ENSMUSG00000022962

Description: phosphoribosylglycinamide formyltransferase

Associated with

Metabolism
(R-MMU-1430728)
Metabolism of nucleotides
(R-MMU-15869)
Nucleotide biosynthesis
(R-MMU-8956320)
Purine ribonucleoside monophosphate biosynthesis
(R-MMU-73817)
'de novo' amp biosynthetic process
(GO:0044208)
'de novo' imp biosynthetic process
(GO:0006189)
'de novo' xmp biosynthetic process
(GO:0097294)
Adenine biosynthetic process
(GO:0046084)
Atp binding
(GO:0005524)
Biosynthetic process
(GO:0009058)
Catalytic activity
(GO:0003824)
Cytosol
(GO:0005829)
Glycine metabolic process
(GO:0006544)
Gmp biosynthetic process
(GO:0006177)
Ligase activity
(GO:0016874)
Metabolic process
(GO:0008152)
Metal ion binding
(GO:0046872)
Nucleotide binding
(GO:0000166)
Phosphoribosylamine-glycine ligase activity
(GO:0004637)
Phosphoribosylformylglycinamidine cyclo-ligase activity
(GO:0004641)
Phosphoribosylglycinamide formyltransferase activity
(GO:0004644)
Purine nucleobase biosynthetic process
(GO:0009113)
Purine nucleotide biosynthetic process
(GO:0006164)
Response to inorganic substance
(GO:0010035)
Response to organic substance
(GO:0010033)
Tetrahydrofolate biosynthetic process
(GO:0046654)
Transferase activity
(GO:0016740)

Other Information

Proteins

Glycinamide ribonucleotide synthetase

Genular Protein ID: 1698077136

Symbol: PUR2_MOUSE

Name: Glycinamide ribonucleotide synthetase

UniProtKB Accession Codes:

Q64737 Q3TGI3 Q6NS48

Database IDs:

Citations:

PubMed ID: 8299947

Title: Mouse cDNAs encoding a trifunctional protein of de novo purine synthesis and a related single-domain glycinamide ribonucleotide synthetase.

PubMed ID: 8299947

DOI: 10.1016/0378-1119(93)90006-o

PubMed ID: 7829519

Title: Analysis of a mouse gene encoding three steps of purine synthesis reveals use of an intronic polyadenylation signal without alternative exon usage.

PubMed ID: 7829519

DOI: 10.1074/jbc.270.4.1823

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

Sequence Information:

Length: 1010
Mass: 107503
Checksum: 894D7D07D3C258B2
Sequence:

MAARVLVIGS GGREHTLAWK LAQSPQVKQV LVAPGNAGTA CAGKISNAAV SVNDHSALAQ 
FCKDEKIELV VVGPEAPLAA GIVGDLTSAG VRCFGPTAQA AQLESSKKFA KEFMDRHEIP 
TAQWRAFTNP EDACSFITSA NFPALVVKAS GLAAGKGVIV AKSQAEACRA VQEIMQEKSF 
GAAGETVVVE EFLEGEEVSC LCFTDGKTVA EMPPAQDHKR LLDGDEGPNT GGMGAYCPAP 
QVSKDLLVKI KNTILQRAVD GMQQEGAPYT GILYAGIMLT KDGPKVLEFN CRFGDPECQV 
ILPLLKSDLY EVMQSTLDGL LSASLPVWLE NHSAVTVVMA SKGYPGAYTK GVEITGFPEA 
QALGLQVFHA GTALKDGKVV TSGGRVLTVT AVQENLMSAL AEARKGLAAL KFEGAIYRKD 
IGFRAVAFLQ RPRGLTYKDS GVDIAAGNML VKKIQPLAKA TSRPGCSVDL GGFAGLFDLK 
AAGFKDPLLA SGTDGVGTKL KIAQLCNKHD SIGQDLVAMC VNDILAQGAE PLFFLDYFSC 
GKLDLSTTEA VIAGIAAACQ QAGCALLGGE TAEMPNMYPP GEYDLAGFAV GAMERHQKLP 
QLERITEGDA VIGVASSGLH SNGFSLVRKI VERSSLQYSS PAPGGCGDQT LGDLLLTPTR 
IYSHSLLPII RSGRVKAFAH ITGGGLLENI PRVLPQKFGV DLDASTWRVP KVFSWLQQEG 
ELSEEEMART FNCGIGAALV VSKDQAEQVL HDVRRRQEEA WVIGSVVACP EDSPRVRVKN 
LIETIQTNGS LVANGFLKSN FPVQQKKARV AVLISGTGSN LQALIDSTRD PKSSSHIVLV 
ISNKAAVAGL DRAERAGIPT RVINHKLYKN RVEFDNAVDH VLEEFSVDIV CLAGFMRILS 
GPFVRKWDGK MLNIHPSLLP SFKGSNAHEQ VLEAGVTITG CTVHFVAEDV DAGQIILQEA 
VPVRRGDTVA TLSERVKVAE HKIFPAALQL VASGAVQLRE DGKIHWAKEQ

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Gart

Associated with

Other Information

Mouse cDNAs encoding a trifunctional protein of de novo purine synthesis and a related single-domain glycinamide ribonucleotide synthetase. PubMed ID: 8299947

Analysis of a mouse gene encoding three steps of purine synthesis reveals use of an intronic polyadenylation signal without alternative exon usage. PubMed ID: 7829519

The transcriptional landscape of the mammalian genome. PubMed ID: 16141072