Details for: Gbx2

Gene ID: 14472

Symbol: Gbx2

Ensembl ID: ENSMUSG00000034486

Description: gastrulation brain homeobox 2

Associated with

  • Autonomic nervous system development
    (GO:0048483)
  • Axon guidance
    (GO:0007411)
  • Branching involved in blood vessel morphogenesis
    (GO:0001569)
  • Cerebellar granule cell precursor proliferation
    (GO:0021930)
  • Cerebellum development
    (GO:0021549)
  • Dna-binding transcription activator activity, rna polymerase ii-specific
    (GO:0001228)
  • Dna-binding transcription factor activity, rna polymerase ii-specific
    (GO:0000981)
  • Dna binding
    (GO:0003677)
  • Forebrain neuron development
    (GO:0021884)
  • Hindbrain development
    (GO:0030902)
  • Inner ear morphogenesis
    (GO:0042472)
  • Midbrain-hindbrain boundary development
    (GO:0030917)
  • Midbrain-hindbrain boundary morphogenesis
    (GO:0021555)
  • Neural crest cell migration
    (GO:0001755)
  • Nucleoplasm
    (GO:0005654)
  • Nucleus
    (GO:0005634)
  • Positive regulation of transcription by rna polymerase ii
    (GO:0045944)
  • Regulation of dna-templated transcription
    (GO:0006355)
  • Regulation of nervous system development
    (GO:0051960)
  • Regulation of transcription by rna polymerase ii
    (GO:0006357)
  • Rhombomere 2 development
    (GO:0021568)
  • Rna polymerase ii-specific dna-binding transcription factor binding
    (GO:0061629)
  • Rna polymerase ii core promoter sequence-specific dna binding
    (GO:0000979)
  • Rna polymerase ii transcription regulatory region sequence-specific dna binding
    (GO:0000977)
  • Sequence-specific double-stranded dna binding
    (GO:1990837)
  • Thalamus development
    (GO:0021794)
  • Tube morphogenesis
    (GO:0035239)

Other Information

Genular Protein ID: 2731585288

Symbol: GBX2_MOUSE

Name: Homeobox protein GBX-2

UniProtKB Accession Codes:

P48031 Q14A66

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CCDS 1 CDD 1 CTD 1 ChiTaRS 1 DNASU 1 EMBL 6 Ensembl 1 GO 24 Gene3D 1 GeneTree 1 Genevisible 1 HOGENOM 1 InParanoid 1 InterPro 5 KEGG 1 MGI 1 NCBI Taxonomy 1 OMA 1 OrthoDB 1 PANTHER 2 PIR 1 PRINTS 1 PRO 1 PROSITE 2 PROSITE-ProRule 1 PaxDb 1 Pfam 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 RNAct 1 RefSeq 1 SAM 1 SMART 1 SMR 1 STRING 1 SUPFAM 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1

Citations:

PubMed ID: 8601031

Title: Sequence and expression pattern of the Stra7 (Gbx-2) homeobox-containing gene induced by retinoic acid in P19 embryonal carcinoma cells.

PubMed ID: 8601031

DOI: 10.1002/aja.1002040404

PubMed ID: 9417909

Title: The mouse homeobox gene, Gbx2: genomic organization and expression in pluripotent cells in vitro and in vivo.

PubMed ID: 9417909

DOI: 10.1006/geno.1997.4969

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 7758585

Title: Sequence and evolutionary conservation of the murine Gbx-2 homeobox gene.

PubMed ID: 7758585

DOI: 10.1016/0014-5793(95)00410-b

PubMed ID: 1720547

Title: Detection of homeobox genes in development and evolution.

PubMed ID: 1720547

DOI: 10.1073/pnas.88.23.10711

Sequence Information:

  • Length: 348
  • Mass: 37359
  • Checksum: CF8594653EA8295B
  • Sequence:
    • MSAAFPPSLM MMQRPLGSST AFSIDSLIGS PPQPSPGHFV YTGYPMFMPY RPVVLPPPPP 
PPPALPQAAL QPALPPAHPH HQIPSLPTGF CSSLAQGMAL TSTLMATLPG GFSASPQHQE 
AAAARKFAPQ PLPGGGNFDK AEALQADAED GKAFLAKEGS LLAFSAAEAV QASLVGAVRG 
QGKDESKVED DPKGKEESFS LESDVDYSSD DNLPGQTAHK EEDPGHALEE TPQSGGAAGS 
TTSTGKNRRR RTAFTSEQLL ELEKEFHCKK YLSLTERSQI AHALKLSEVQ VKIWFQNRRA 
KWKRVKAGNA NSKTGEPSRN PKIVVPIPVH VSRFAIRSQH QQLEQARP

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.