Genular: Defining Cellular Identity and Function

Details for: Usp15

Gene ID: 14479

Symbol: Usp15

Ensembl ID: ENSMUSG00000020124

Description: ubiquitin specific peptidase 15

Associated with

Deubiquitination
(R-MMU-5688426)
Metabolism of proteins
(R-MMU-392499)
Post-translational protein modification
(R-MMU-597592)
Ub-specific processing proteases
(R-MMU-5689880)
Bmp signaling pathway
(GO:0030509)
Catalytic activity
(GO:0003824)
Cysteine-type deubiquitinase activity
(GO:0004843)
Cysteine-type endopeptidase activity
(GO:0004197)
Cysteine-type peptidase activity
(GO:0008234)
Cytoplasm
(GO:0005737)
Cytosol
(GO:0005829)
Deubiquitinase activity
(GO:0101005)
Hydrolase activity
(GO:0016787)
Identical protein binding
(GO:0042802)
K48-linked deubiquitinase activity
(GO:1990380)
Mitochondrion
(GO:0005739)
Monoubiquitinated protein deubiquitination
(GO:0035520)
Negative regulation of antifungal innate immune response
(GO:1905035)
Negative regulation of transforming growth factor beta receptor signaling pathway
(GO:0030512)
Nuclear body
(GO:0016604)
Nucleoplasm
(GO:0005654)
Nucleus
(GO:0005634)
Peptidase activity
(GO:0008233)
Positive regulation of rig-i signaling pathway
(GO:1900246)
Protein deubiquitination
(GO:0016579)
Protein k27-linked deubiquitination
(GO:1990167)
Proteolysis
(GO:0006508)
Regulation of intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator
(GO:1902238)
Smad binding
(GO:0046332)
Transcription elongation-coupled chromatin remodeling
(GO:0140673)
Transforming growth factor beta receptor binding
(GO:0005160)
Transforming growth factor beta receptor signaling pathway
(GO:0007179)
Ubiquitin modification-dependent histone binding
(GO:0061649)

Other Information

Proteins

Ubiquitin carboxyl-terminal hydrolase 15
Q3TSV9_MOUSE

Genular Protein ID: 3264134471

Symbol: UBP15_MOUSE

Name: Ubiquitin carboxyl-terminal hydrolase 15

UniProtKB Accession Codes:

Q8R5H1 Q3TGF5 Q3TTB2 Q3UL25 Q3UZH0 Q80TY6 Q80UK9

Database IDs:

Citations:

PubMed ID: 12532266

Title: Isolation and characterization of the mouse ubiquitin-specific protease Usp15.

PubMed ID: 12532266

DOI: 10.1007/s00335-002-3035-0

PubMed ID: 12693553

Title: Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

PubMed ID: 12693553

DOI: 10.1093/dnares/10.1.35

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 17242355

Title: Large-scale phosphorylation analysis of mouse liver.

PubMed ID: 17242355

DOI: 10.1073/pnas.0609836104

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

PubMed ID: 24852371

Title: The deubiquitinase USP15 antagonizes Parkin-mediated mitochondrial ubiquitination and mitophagy.

PubMed ID: 24852371

DOI: 10.1093/hmg/ddu244

Sequence Information:

Length: 981
Mass: 112325
Checksum: 6D5377C3FEA6E40A
Sequence:

MAEGGAADLD TQRSDIATLL KTSLRKGDTW YLVDSRWFKQ WKKYVGFDSW DKYQMGDQNV 
YPGPIDNSGL LKDGDAQSLK EHLIDELDYI LLPTEGWNKL VSWYTLMEGQ EPIARKVVEQ 
GMFVKHCKVE VYLTELKLCE NGNMNNVVTR RFSKADTIDT IEKEIRKIFN IPDEKEARLW 
NKYMSNTFEP LNKPDSTIQD AGLYQGQVLV IEQKNEDGTW PRGPSTPKSP GASNFSTLPK 
ISPSSLSNNY NNINNRNVKN SNYCLPSYTA YKNYDYSEPG RNNEQPGLCG LSNLGNTCFM 
NSAIQCLSNT PPLTEYFLND KYQEELNFDN PLGMRGEIAK SYAELIKQMW SGKFSYVTPR 
AFKTQVGRFA PQFSGYQQQD CQELLAFLLD GLHEDLNRIR KKPYIQLKDA DGRPDKVVAE 
EAWENHLKRN DSIIVDIFHG LFKSTLVCPE CAKISVTFDP FCYLTLPLPM KKERSLEVYL 
VRMDPLAKPM QYKVIVPKIG NILDLCTALS ALSGVPADKM IVTDIYNHRF HRIFAVDENL 
SSIMERDDIY VFEININRAE DTEHVVIPVC LREKFRHSSY THHTGSSLFG QPFLMAIPRN 
NTEDKLYNLL LLRMCRYVKM STETEETDGH LRCCEDQNIN GNGPNGLHEE GSPSEMETDE 
PDDESSQDQE LPSENENSQS EDSVGGDNDS ENGLCTEETC KGQLTGHKKR LFTFQFNNLG 
NNDINYIKDD TSHIRFDDRQ LRLDERSFLA LDWDPDLKKR YFDENAAEDF EKHESVEYKP 
PKRPFVKLKD CIELFTTKEK LGAEDPWYCP NCKEHQQATK KLDLWSLPPV LVVHLKRFSY 
SRYMRDKLDT LVDFPISDLD MSEFLINPNA GPCRYNLIAV SNHYGGMGGG HYTAFAKNKD 
DGKWYYFDDS SVSTASEDQI VSKAAYVLFY QRQDTFSGTG FFPLDRETKG ASAATGIPLE 
SDEDSNDNDN DLENENCMHT N

Genular Protein ID: 4172816758

Symbol: Q3TSV9_MOUSE

Name: N/A

UniProtKB Accession Codes:

Q3TSV9

Database IDs:

Citations:

PubMed ID: 10349636

Title: High-efficiency full-length cDNA cloning.

PubMed ID: 10349636

DOI: 10.1016/S0076-6879(99)03004-9

PubMed ID: 11042159

Title: Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes.

PubMed ID: 11042159

DOI: 10.1101/gr.145100

PubMed ID: 11076861

Title: RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer.

PubMed ID: 11076861

DOI: 10.1101/gr.152600

PubMed ID: 11217851

Title: Functional annotation of a full-length mouse cDNA collection.

PubMed ID: 11217851

DOI: 10.1038/35055500

PubMed ID: 12466851

Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.

PubMed ID: 12466851

DOI: 10.1038/nature01266

PubMed ID: 16141073

Title: Antisense Transcription in the Mammalian Transcriptome.

PubMed ID: 16141073

DOI: 10.1126/science.1112009

Sequence Information:

Length: 306
Mass: 35098
Checksum: 1E1C89B3B6C910F2
Sequence:

KNSQSEDSVG GDNDSENGLC TEETCKGQLT GHKKRLFTFQ FNNLGNNDIN YIKDDTSHIR 
FDDRQLRLDE RSFLALDWDP DLKKRYFDEN AAEDFEKHES VEYKPPKRPF VKLKDCIELF 
TTKEKLGAED PWYCPNCKEH QQATKKLDLW SLPPVLVVHL KRFSYSRYMR DKLDTLVDFP 
ISDLDMSEFL INPNAGPCRY NLIAVSNHYG GMGGGHYTAF AKNKDDGKWY YFDDSSVSTA 
SEDQIVSKAA YVLFYQRQDT FSGTGFFPLD RETKGASAAT GIPLESDEDS NDNDNDLENE 
NCMHTN

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Usp15

Associated with

Other Information

Isolation and characterization of the mouse ubiquitin-specific protease Usp15. PubMed ID: 12532266

Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries. PubMed ID: 12693553

The transcriptional landscape of the mammalian genome. PubMed ID: 16141072

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Large-scale phosphorylation analysis of mouse liver. PubMed ID: 17242355

A tissue-specific atlas of mouse protein phosphorylation and expression. PubMed ID: 21183079

The deubiquitinase USP15 antagonizes Parkin-mediated mitochondrial ubiquitination and mitophagy. PubMed ID: 24852371

High-efficiency full-length cDNA cloning. PubMed ID: 10349636

Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes. PubMed ID: 11042159

RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer. PubMed ID: 11076861

Functional annotation of a full-length mouse cDNA collection. PubMed ID: 11217851

Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. PubMed ID: 12466851

Antisense Transcription in the Mammalian Transcriptome. PubMed ID: 16141073