Details for: CSNK1A1

Gene ID: 1452

Symbol: CSNK1A1

Ensembl ID: ENSG00000113712

Description: casein kinase 1 alpha 1

Associated with

Other Information

Genular Protein ID: 1409055714

Symbol: KC1A_HUMAN

Name: Casein kinase I isoform alpha

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 8050587

Title: Cloning and chromosomal localization of the gene coding for human protein kinase CK1.

PubMed ID: 8050587

DOI: 10.1016/0014-5793(94)00679-2

PubMed ID: 7797465

Title: Isolation and characterization of human casein kinase I epsilon (CKI), a novel member of the CKI gene family.

PubMed ID: 7797465

DOI: 10.1074/jbc.270.25.14875

PubMed ID: 15498874

Title: Large-scale cDNA transfection screening for genes related to cancer development and progression.

PubMed ID: 15498874

DOI: 10.1073/pnas.0404089101

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 15372022

Title: The DNA sequence and comparative analysis of human chromosome 5.

PubMed ID: 15372022

DOI: 10.1038/nature02919

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 1409656

Title: Cell cycle-dependent localization of casein kinase I to mitotic spindles.

PubMed ID: 1409656

DOI: 10.1073/pnas.89.20.9454

PubMed ID: 11955436

Title: Control of beta-catenin phosphorylation/degradation by a dual-kinase mechanism.

PubMed ID: 11955436

DOI: 10.1016/s0092-8674(02)00685-2

PubMed ID: 16964243

Title: A probability-based approach for high-throughput protein phosphorylation analysis and site localization.

PubMed ID: 16964243

DOI: 10.1038/nbt1240

PubMed ID: 18305108

Title: CKIalpha is associated with and phosphorylates star-PAP and is also required for expression of select star-PAP target messenger RNAs.

PubMed ID: 18305108

DOI: 10.1074/jbc.m800656200

PubMed ID: 18691976

Title: Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle.

PubMed ID: 18691976

DOI: 10.1016/j.molcel.2008.07.007

PubMed ID: 19413330

Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.

PubMed ID: 19413330

DOI: 10.1021/ac9004309

PubMed ID: 19369195

Title: Large-scale proteomics analysis of the human kinome.

PubMed ID: 19369195

DOI: 10.1074/mcp.m800588-mcp200

PubMed ID: 19608861

Title: Lysine acetylation targets protein complexes and co-regulates major cellular functions.

PubMed ID: 19608861

DOI: 10.1126/science.1175371

PubMed ID: 20068231

Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.

PubMed ID: 20068231

DOI: 10.1126/scisignal.2000475

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 22017875

Title: mTOR drives its own activation via SCF(betaTrCP)-dependent degradation of the mTOR inhibitor DEPTOR.

PubMed ID: 22017875

DOI: 10.1016/j.molcel.2011.08.030

PubMed ID: 22017877

Title: mTOR generates an auto-amplification loop by triggering the betaTrCP- and CK1alpha-dependent degradation of DEPTOR.

PubMed ID: 22017877

DOI: 10.1016/j.molcel.2011.09.005

PubMed ID: 22814378

Title: N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.

PubMed ID: 22814378

DOI: 10.1073/pnas.1210303109

PubMed ID: 23902688

Title: A novel mechanism of keratin cytoskeleton organization through casein kinase Ialpha and FAM83H in colorectal cancer.

PubMed ID: 23902688

DOI: 10.1242/jcs.129684

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 31338967

Title: FAM83D directs protein kinase CK1alpha to the mitotic spindle for proper spindle positioning.

PubMed ID: 31338967

DOI: 10.15252/embr.201847495

PubMed ID: 17344846

Title: Patterns of somatic mutation in human cancer genomes.

PubMed ID: 17344846

DOI: 10.1038/nature05610

Sequence Information:

  • Length: 337
  • Mass: 38915
  • Checksum: 1B2085AE33CAFAC2
  • Sequence:
  • MASSSGSKAE FIVGGKYKLV RKIGSGSFGD IYLAINITNG EEVAVKLESQ KARHPQLLYE 
    SKLYKILQGG VGIPHIRWYG QEKDYNVLVM DLLGPSLEDL FNFCSRRFTM KTVLMLADQM 
    ISRIEYVHTK NFIHRDIKPD NFLMGIGRHC NKLFLIDFGL AKKYRDNRTR QHIPYREDKN 
    LTGTARYASI NAHLGIEQSR RDDMESLGYV LMYFNRTSLP WQGLKAATKK QKYEKISEKK 
    MSTPVEVLCK GFPAEFAMYL NYCRGLRFEE APDYMYLRQL FRILFRTLNH QYDYTFDWTM 
    LKQKAAQQAA SSSGQGQQAQ TPTGKQTDKT KSNMKGF

Genular Protein ID: 4000886458

Symbol: B4DER9_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Sequence Information:

  • Length: 276
  • Mass: 32111
  • Checksum: E70965BC2ACCEC20
  • Sequence:
  • MDLLGPSLED LFNFCSRRFT MKTVLMLADQ MISRIEYVHT KNFIHRDIKP DNFLMGIGRH 
    CNKCLESPVG KRKRSMTVST SQDPSFSGLN QLFLIDFGLA KKYRDNRTRQ HIPYREDKNL 
    TGTARYASIN AHLGIEQSRR DDMESLGYVL MYFNRTSLPW QGLKAATKKQ KYEKISEKKM 
    STPVEVLCKG FPAEFAMYLN YCRGLRFEEA PDYMYLRQLF RILFRTLNHQ YDYTFDWTML 
    KQKAAQQAAS SSGQGQQAQT PTGKQTDKTK SNMKGF

Genular Protein ID: 3412915521

Symbol: Q6PJ06_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

Sequence Information:

  • Length: 261
  • Mass: 29825
  • Checksum: 593D1C33EAFF6C43
  • Sequence:
  • MASSSGSKAE FIVGGKYKLV RKIGSGSFGD IYLAINITNG EEVAVKLESQ KARHPQLLYE 
    SKLYKILQGG VGIPHIRWYG QEKDYNVLVM DLLGPSLEDL FNFCSRRFTM KTVLMLADQM 
    ISRIEYVHTK NFIHRDIKPD NFLMGIGRHC NKCLESPVGK RKRSMTVSTS QDPSFSGLNQ 
    LFLIDFGLAK KYRDNRTRQH IPYREDKNLT GTARYASINA HLGIEQSRRD DMESLGYVLM 
    YFNRTSLPWQ GLKAATKKKK K

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.