Details for: CSNK1A1

Gene ID: 1452

Symbol: CSNK1A1

Ensembl ID: ENSG00000113712

Description: casein kinase 1 alpha 1

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 743.7708
    Cell Significance Index: -115.6900
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 458.3207
    Cell Significance Index: -116.2500
  • Cell Name: smooth muscle fiber of ileum (CL1000278)
    Fold Change: 283.4221
    Cell Significance Index: -133.8100
  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 268.9922
    Cell Significance Index: -109.2800
  • Cell Name: peripheral blood mononuclear cell (CL2000001)
    Fold Change: 244.0972
    Cell Significance Index: -125.5600
  • Cell Name: ileal goblet cell (CL1000326)
    Fold Change: 199.6953
    Cell Significance Index: -134.0000
  • Cell Name: ciliated cell of the bronchus (CL0002332)
    Fold Change: 115.1095
    Cell Significance Index: -109.9000
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 102.4611
    Cell Significance Index: -126.3300
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 46.0084
    Cell Significance Index: -123.2500
  • Cell Name: epidermal Langerhans cell (CL0002457)
    Fold Change: 35.0180
    Cell Significance Index: -76.6400
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 32.9089
    Cell Significance Index: -129.8600
  • Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
    Fold Change: 32.6360
    Cell Significance Index: -100.2400
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: 6.7453
    Cell Significance Index: 180.1100
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: 3.9243
    Cell Significance Index: 109.6700
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: 3.8229
    Cell Significance Index: 284.9200
  • Cell Name: luminal hormone-sensing cell of mammary gland (CL4033058)
    Fold Change: 3.5667
    Cell Significance Index: 21.9500
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: 3.2359
    Cell Significance Index: 44.1500
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 3.2072
    Cell Significance Index: 394.3600
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 3.0200
    Cell Significance Index: 544.4200
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 3.0016
    Cell Significance Index: 230.3400
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: 2.6551
    Cell Significance Index: 72.2700
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: 2.4015
    Cell Significance Index: 112.8700
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 2.3777
    Cell Significance Index: 471.8700
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 2.2676
    Cell Significance Index: 454.8700
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 2.0514
    Cell Significance Index: 735.7900
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 2.0449
    Cell Significance Index: 280.8200
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 1.8823
    Cell Significance Index: 832.2300
  • Cell Name: lactocyte (CL0002325)
    Fold Change: 1.8558
    Cell Significance Index: 239.7500
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: 1.8515
    Cell Significance Index: 96.4400
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 1.8203
    Cell Significance Index: 994.1300
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: 1.7159
    Cell Significance Index: 96.2900
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: 1.6914
    Cell Significance Index: 103.9600
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 1.1066
    Cell Significance Index: 50.1600
  • Cell Name: odontoblast (CL0000060)
    Fold Change: 0.9942
    Cell Significance Index: 127.4500
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 0.9893
    Cell Significance Index: 684.2300
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: 0.9227
    Cell Significance Index: 43.0200
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: 0.9120
    Cell Significance Index: 64.5000
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: 0.8027
    Cell Significance Index: 23.0100
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.7620
    Cell Significance Index: 21.9600
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: 0.7387
    Cell Significance Index: 47.6600
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.7297
    Cell Significance Index: 72.1800
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: 0.6015
    Cell Significance Index: 70.9300
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: 0.4201
    Cell Significance Index: 14.6000
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: 0.4136
    Cell Significance Index: 27.8100
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.3489
    Cell Significance Index: 656.9200
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 0.3011
    Cell Significance Index: 15.6400
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: 0.2699
    Cell Significance Index: 171.4100
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: 0.2232
    Cell Significance Index: 303.5600
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 0.2151
    Cell Significance Index: 7.5600
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: 0.2031
    Cell Significance Index: 5.2200
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: 0.1234
    Cell Significance Index: 55.9900
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 0.0983
    Cell Significance Index: 151.2900
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 0.0625
    Cell Significance Index: 115.3200
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.0580
    Cell Significance Index: 11.0400
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: 0.0519
    Cell Significance Index: 8.8600
  • Cell Name: cardiac muscle cell (CL0000746)
    Fold Change: 0.0061
    Cell Significance Index: 0.0900
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.0006
    Cell Significance Index: 0.0900
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: -0.0137
    Cell Significance Index: -0.7200
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0474
    Cell Significance Index: -34.7300
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0614
    Cell Significance Index: -46.4600
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0617
    Cell Significance Index: -45.7200
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: -0.0648
    Cell Significance Index: -58.5300
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.1094
    Cell Significance Index: -68.3400
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: -0.1147
    Cell Significance Index: -5.0700
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: -0.1354
    Cell Significance Index: -2.3200
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.1605
    Cell Significance Index: -16.3900
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.1717
    Cell Significance Index: -96.8100
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: -0.2438
    Cell Significance Index: -4.0800
  • Cell Name: umbrella cell of urothelium (CL4030056)
    Fold Change: -0.2465
    Cell Significance Index: -2.2700
  • Cell Name: peg cell (CL4033014)
    Fold Change: -0.2619
    Cell Significance Index: -6.0500
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: -0.2677
    Cell Significance Index: -7.0400
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.3089
    Cell Significance Index: -65.0700
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: -0.3742
    Cell Significance Index: -14.1700
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.3954
    Cell Significance Index: -57.4800
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.4031
    Cell Significance Index: -115.9800
  • Cell Name: type I muscle cell (CL0002211)
    Fold Change: -0.5340
    Cell Significance Index: -13.0300
  • Cell Name: cortical interneuron (CL0008031)
    Fold Change: -0.5604
    Cell Significance Index: -13.4400
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.6089
    Cell Significance Index: -70.9600
  • Cell Name: pancreatic endocrine cell (CL0008024)
    Fold Change: -0.7232
    Cell Significance Index: -82.5600
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.8434
    Cell Significance Index: -96.6200
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.8972
    Cell Significance Index: -93.4200
  • Cell Name: endothelial cell of placenta (CL0009092)
    Fold Change: -0.9716
    Cell Significance Index: -5.8700
  • Cell Name: preadipocyte (CL0002334)
    Fold Change: -1.0283
    Cell Significance Index: -20.0700
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: -1.2335
    Cell Significance Index: -85.3100
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: -1.2771
    Cell Significance Index: -80.4900
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -1.3110
    Cell Significance Index: -103.8300
  • Cell Name: leptomeningeal cell (CL0000708)
    Fold Change: -1.4009
    Cell Significance Index: -29.9500
  • Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
    Fold Change: -1.5029
    Cell Significance Index: -27.7800
  • Cell Name: fibro/adipogenic progenitor cell (CL0009099)
    Fold Change: -1.5165
    Cell Significance Index: -76.6400
  • Cell Name: basal epithelial cell of prostatic duct (CL0002236)
    Fold Change: -1.5310
    Cell Significance Index: -13.5900
  • Cell Name: fibroblast of dermis (CL0002551)
    Fold Change: -1.5465
    Cell Significance Index: -32.3700
  • Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
    Fold Change: -1.6517
    Cell Significance Index: -48.5100
  • Cell Name: hippocampal pyramidal neuron (CL1001571)
    Fold Change: -1.7427
    Cell Significance Index: -49.7300
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: -1.8002
    Cell Significance Index: -39.0000
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -1.9720
    Cell Significance Index: -120.9000
  • Cell Name: vascular lymphangioblast (CL0005022)
    Fold Change: -2.0089
    Cell Significance Index: -35.5000
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: -2.0219
    Cell Significance Index: -54.0900
  • Cell Name: pro-T cell (CL0000827)
    Fold Change: -2.0899
    Cell Significance Index: -53.3900
  • Cell Name: endothelial cell of venule (CL1000414)
    Fold Change: -2.1188
    Cell Significance Index: -24.0700
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: -2.1787
    Cell Significance Index: -46.4000

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics** CSNK1A1 is a member of the casein kinase 1 (CK1) family, which is characterized by its ability to phosphorylate serine and threonine residues on target proteins. CSNK1A1 is a multi-functional kinase that exhibits a wide range of substrate specificity, including proteins involved in cell signaling, protein degradation, and cytoskeletal organization. Its activity is tightly regulated by various post-translational modifications, including phosphorylation, ubiquitination, and proteasomal degradation. **Pathways and Functions** CSNK1A1 is involved in numerous cellular signaling pathways, including: 1. **Wnt signaling pathway**: CSNK1A1 phosphorylates and regulates key proteins involved in the Wnt signaling pathway, including beta-catenin, axin, and Gli3. This regulates the activation or inhibition of Wnt-dependent transcriptional programs. 2. **Cell cycle and cell division**: CSNK1A1 phosphorylates and regulates proteins involved in the cell cycle, including cyclin-dependent kinases and cyclin-dependent kinase inhibitors. This regulates the progression of cells through the cell cycle and prevents uncontrolled cell proliferation. 3. **Protein degradation**: CSNK1A1 regulates the activity of proteasomes, which are responsible for the degradation of ubiquitinated proteins. This regulates the levels of specific proteins within the cell and modulates cellular signaling. 4. **Cytoskeletal organization**: CSNK1A1 phosphorylates and regulates proteins involved in cytoskeletal organization, including actin and tubulin. This regulates the structure and dynamics of the cytoskeleton, which is essential for cell shape, movement, and division. **Clinical Significance** CSNK1A1 has been implicated in various diseases, including: 1. **Cancer**: CSNK1A1 has been shown to regulate the Wnt signaling pathway, which is often dysregulated in cancer. Elevated levels of CSNK1A1 have been associated with various types of cancer, including colorectal, breast, and prostate cancer. 2. **Inflammatory disorders**: CSNK1A1 has been shown to regulate the activity of proteasomes, which are involved in the degradation of inflammatory proteins. Elevated levels of CSNK1A1 have been associated with inflammatory disorders, including rheumatoid arthritis and psoriasis. 3. **Viral infections**: CSNK1A1 has been shown to regulate the activity of proteasomes, which are involved in the degradation of viral proteins. Elevated levels of CSNK1A1 have been associated with viral infections, including SARS-CoV-2 and HIV-1. In conclusion, CSNK1A1 is a multi-functional kinase that plays a critical role in various cellular signaling pathways, including the Wnt signaling pathway, cell cycle, protein degradation, and cytoskeletal organization. Its dysregulation has been implicated in various diseases, including cancer, inflammatory disorders, and viral infections, highlighting the importance of this enzyme in maintaining cellular homeostasis and preventing disease.

Genular Protein ID: 1409055714

Symbol: KC1A_HUMAN

Name: Casein kinase I isoform alpha

UniProtKB Accession Codes:

P48729 D3DQG0 D3DQG1 Q4JJA0 Q5U046 Q5U047 Q6FGA2 Q71TU5 Q96HD2 Q9UDK3

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 BRENDA 1 Bgee 1 BindingDB 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 3 CDD 1 CPTAC 2 CTD 1 ChEBI 12 ChEMBL 1 ChiTaRS 1 ComplexPortal 8 DIP 1 DMDM 1 DNASU 1 DisGeNET 1 DrugBank 1 DrugCentral 1 EC 2 EMBL 15 EMDB 1 Ensembl 3 ExpressionAtlas 1 GO 30 Gene3D 1 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyGen 1 GuidetoPHARMACOLOGY 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 5 KEGG 1 MANE-Select 1 MIM 1 MINT 1 MassIVE 1 MetOSite 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PDB 4 PDBsum 4 PIR 2 PRO 1 PROSITE 3 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 1 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 3 Pumba 1 RNAct 1 Reactome 15 RefSeq 4 Rhea 7 SIGNOR 1 SMART 1 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 SwissPalm 1 TopDownProteomics 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 8050587

Title: Cloning and chromosomal localization of the gene coding for human protein kinase CK1.

PubMed ID: 8050587

DOI: 10.1016/0014-5793(94)00679-2

PubMed ID: 7797465

Title: Isolation and characterization of human casein kinase I epsilon (CKI), a novel member of the CKI gene family.

PubMed ID: 7797465

DOI: 10.1074/jbc.270.25.14875

PubMed ID: 15498874

Title: Large-scale cDNA transfection screening for genes related to cancer development and progression.

PubMed ID: 15498874

DOI: 10.1073/pnas.0404089101

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 15372022

Title: The DNA sequence and comparative analysis of human chromosome 5.

PubMed ID: 15372022

DOI: 10.1038/nature02919

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 1409656

Title: Cell cycle-dependent localization of casein kinase I to mitotic spindles.

PubMed ID: 1409656

DOI: 10.1073/pnas.89.20.9454

PubMed ID: 11955436

Title: Control of beta-catenin phosphorylation/degradation by a dual-kinase mechanism.

PubMed ID: 11955436

DOI: 10.1016/s0092-8674(02)00685-2

PubMed ID: 16964243

Title: A probability-based approach for high-throughput protein phosphorylation analysis and site localization.

PubMed ID: 16964243

DOI: 10.1038/nbt1240

PubMed ID: 18305108

Title: CKIalpha is associated with and phosphorylates star-PAP and is also required for expression of select star-PAP target messenger RNAs.

PubMed ID: 18305108

DOI: 10.1074/jbc.m800656200

PubMed ID: 18691976

Title: Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle.

PubMed ID: 18691976

DOI: 10.1016/j.molcel.2008.07.007

PubMed ID: 19413330

Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.

PubMed ID: 19413330

DOI: 10.1021/ac9004309

PubMed ID: 19369195

Title: Large-scale proteomics analysis of the human kinome.

PubMed ID: 19369195

DOI: 10.1074/mcp.m800588-mcp200

PubMed ID: 19608861

Title: Lysine acetylation targets protein complexes and co-regulates major cellular functions.

PubMed ID: 19608861

DOI: 10.1126/science.1175371

PubMed ID: 20068231

Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.

PubMed ID: 20068231

DOI: 10.1126/scisignal.2000475

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 22017875

Title: mTOR drives its own activation via SCF(betaTrCP)-dependent degradation of the mTOR inhibitor DEPTOR.

PubMed ID: 22017875

DOI: 10.1016/j.molcel.2011.08.030

PubMed ID: 22017877

Title: mTOR generates an auto-amplification loop by triggering the betaTrCP- and CK1alpha-dependent degradation of DEPTOR.

PubMed ID: 22017877

DOI: 10.1016/j.molcel.2011.09.005

PubMed ID: 22814378

Title: N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.

PubMed ID: 22814378

DOI: 10.1073/pnas.1210303109

PubMed ID: 23902688

Title: A novel mechanism of keratin cytoskeleton organization through casein kinase Ialpha and FAM83H in colorectal cancer.

PubMed ID: 23902688

DOI: 10.1242/jcs.129684

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 31338967

Title: FAM83D directs protein kinase CK1alpha to the mitotic spindle for proper spindle positioning.

PubMed ID: 31338967

DOI: 10.15252/embr.201847495

PubMed ID: 17344846

Title: Patterns of somatic mutation in human cancer genomes.

PubMed ID: 17344846

DOI: 10.1038/nature05610

Sequence Information:

  • Length: 337
  • Mass: 38915
  • Checksum: 1B2085AE33CAFAC2
  • Sequence:
    • MASSSGSKAE FIVGGKYKLV RKIGSGSFGD IYLAINITNG EEVAVKLESQ KARHPQLLYE 
SKLYKILQGG VGIPHIRWYG QEKDYNVLVM DLLGPSLEDL FNFCSRRFTM KTVLMLADQM 
ISRIEYVHTK NFIHRDIKPD NFLMGIGRHC NKLFLIDFGL AKKYRDNRTR QHIPYREDKN 
LTGTARYASI NAHLGIEQSR RDDMESLGYV LMYFNRTSLP WQGLKAATKK QKYEKISEKK 
MSTPVEVLCK GFPAEFAMYL NYCRGLRFEE APDYMYLRQL FRILFRTLNH QYDYTFDWTM 
LKQKAAQQAA SSSGQGQQAQ TPTGKQTDKT KSNMKGF

Genular Protein ID: 4000886458

Symbol: B4DER9_HUMAN

Name: N/A

UniProtKB Accession Codes:

B4DER9

Database IDs:

ARBA 8 AlphaFoldDB 1 BioGRID-ORCS 1 CTD 1 ChEBI 5 DNASU 1 DisGeNET 1 EC 1 EMBL 2 GO 6 Gene3D 1 InterPro 4 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PROSITE 3 PeptideAtlas 1 Pfam 1 RefSeq 1 Rhea 3 SAM 1 SUPFAM 1

Sequence Information:

  • Length: 276
  • Mass: 32111
  • Checksum: E70965BC2ACCEC20
  • Sequence:
    • MDLLGPSLED LFNFCSRRFT MKTVLMLADQ MISRIEYVHT KNFIHRDIKP DNFLMGIGRH 
CNKCLESPVG KRKRSMTVST SQDPSFSGLN QLFLIDFGLA KKYRDNRTRQ HIPYREDKNL 
TGTARYASIN AHLGIEQSRR DDMESLGYVL MYFNRTSLPW QGLKAATKKQ KYEKISEKKM 
STPVEVLCKG FPAEFAMYLN YCRGLRFEEA PDYMYLRQLF RILFRTLNHQ YDYTFDWTML 
KQKAAQQAAS SSGQGQQAQT PTGKQTDKTK SNMKGF

Genular Protein ID: 3412915521

Symbol: Q6PJ06_HUMAN

Name: N/A

UniProtKB Accession Codes:

Q6PJ06

Database IDs:

ARBA 8 AlphaFoldDB 1 BioGRID-ORCS 1 CTD 1 ChEBI 6 ChiTaRS 1 DNASU 1 DisGeNET 1 EC 1 EMBL 4 GO 6 Gene3D 1 InterPro 5 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PROSITE 4 PROSITE-ProRule 1 PeptideAtlas 1 Pfam 1 PharmGKB 1 RefSeq 1 Rhea 3 RuleBase 1 SMART 1 SUPFAM 1

Citations:

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

Sequence Information:

  • Length: 261
  • Mass: 29825
  • Checksum: 593D1C33EAFF6C43
  • Sequence:
    • MASSSGSKAE FIVGGKYKLV RKIGSGSFGD IYLAINITNG EEVAVKLESQ KARHPQLLYE 
SKLYKILQGG VGIPHIRWYG QEKDYNVLVM DLLGPSLEDL FNFCSRRFTM KTVLMLADQM 
ISRIEYVHTK NFIHRDIKPD NFLMGIGRHC NKCLESPVGK RKRSMTVSTS QDPSFSGLNQ 
LFLIDFGLAK KYRDNRTRQH IPYREDKNLT GTARYASINA HLGIEQSRRD DMESLGYVLM 
YFNRTSLPWQ GLKAATKKKK K

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.