Details for: Gcm1

Gene ID: 14531

Symbol: Gcm1

Ensembl ID: ENSMUSG00000023333

Description: glial cells missing homolog 1

Associated with

  • Astrocyte fate commitment
    (GO:0060018)
  • Branching involved in labyrinthine layer morphogenesis
    (GO:0060670)
  • Cell differentiation involved in embryonic placenta development
    (GO:0060706)
  • Dna-binding transcription activator activity, rna polymerase ii-specific
    (GO:0001228)
  • Dna-binding transcription factor activity
    (GO:0003700)
  • Dna-binding transcription factor activity, rna polymerase ii-specific
    (GO:0000981)
  • Dna binding
    (GO:0003677)
  • Gliogenesis
    (GO:0042063)
  • Histone deacetylase binding
    (GO:0042826)
  • Metal ion binding
    (GO:0046872)
  • Multicellular organism development
    (GO:0007275)
  • Nucleus
    (GO:0005634)
  • Positive regulation of dna-templated transcription
    (GO:0045893)
  • Positive regulation of syncytium formation by plasma membrane fusion
    (GO:0060143)
  • Positive regulation of transcription by rna polymerase ii
    (GO:0045944)
  • Protein binding
    (GO:0005515)
  • Regulation of cell differentiation involved in embryonic placenta development
    (GO:0060800)
  • Regulation of dna-templated transcription
    (GO:0006355)
  • Regulation of transcription by rna polymerase ii
    (GO:0006357)
  • Rna polymerase ii cis-regulatory region sequence-specific dna binding
    (GO:0000978)
  • Sequence-specific double-stranded dna binding
    (GO:1990837)
  • Syncytium formation by plasma membrane fusion
    (GO:0000768)
  • Transcription by rna polymerase ii
    (GO:0006366)
  • Transcription factor binding
    (GO:0008134)
  • Transcription regulator complex
    (GO:0005667)
  • Zinc ion binding
    (GO:0008270)

Other Information

Genular Protein ID: 4160194077

Symbol: GCM1_MOUSE

Name: Chorion-specific transcription factor GCMa

UniProtKB Accession Codes:

P70348 O09103

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CCDS 1 CTD 1 ChEBI 8 ChiTaRS 1 DNASU 1 EMBL 3 Ensembl 1 EvolutionaryTrace 1 ExpressionAtlas 1 GO 22 Gene3D 2 GeneTree 1 Genevisible 1 HOGENOM 1 InParanoid 1 InterPro 5 KEGG 1 MGI 1 NCBI Taxonomy 1 OMA 1 OrthoDB 1 PANTHER 2 PDB 2 PDBsum 1 PIR 1 PRO 1 PROSITE 1 PROSITE-ProRule 1 PaxDb 1 Pfam 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 RNAct 1 RefSeq 1 SMR 1 STRING 1 SUPFAM 1 TreeFam 1 UCSC 1 UniProtKB 1 VEuPathDB 1 eggNOG 1 iPTMnet 1

Citations:

PubMed ID: 8814290

Title: Gcm1, a mammalian homolog of Drosophila glial cells missing.

PubMed ID: 8814290

DOI: 10.1016/0014-5793(96)00890-3

PubMed ID: 8962155

Title: The gcm-motif: a novel DNA binding motif conserved in Drosophila and mammals.

PubMed ID: 8962155

DOI: 10.1073/pnas.93.25.14912

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 12682016

Title: Structure of the GCM domain-DNA complex: a DNA-binding domain with a novel fold and mode of target site recognition.

PubMed ID: 12682016

DOI: 10.1093/emboj/cdg182

Sequence Information:

  • Length: 436
  • Mass: 49589
  • Checksum: 99F4E441800582DB
  • Sequence:
    • MELDDFDPED KEILSWDIND VKLPQNVKTT DWFQEWPDSY VKHIYSSDDR NAQRHLSSWA 
MRNTNNHNSR ILKKSCLGVV VCSRDCSTEE GRKIYLRPAI CDKARQKQQR KSCPNCNGPL 
KLIPCRGHGG FPVTNFWRHD GRFIFFQSKG EHDHPRPETK LEAEARRAMK KVHMASASNS 
LRMKGRPAAK ALPAEIPSQG SLPLTWSFQE GVQLPGTYST PLIANAPQQN SLNDCLSFPK 
SYDLGGSTEL EDPTSTLDSM KFYERCKFSS SRIYGSEEQF QPPVPGTYGD YEDLQTWNKN 
VALGRNPSDD IYYPAYPLPV ASWPYDYFPS QNSLEHLPQQ VPSEPPAAQP GCHPLWSNPG 
GEPYEEKVSV DLSSYVPSLT YHPPQQDPFL LTYGSPTQQQ HALPGKSNRW DFDEEMACMG 
LDHFNNEMLL NFCSLR

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.