Details for: Gcnt1

Gene ID: 14537

Symbol: Gcnt1

Ensembl ID: ENSMUSG00000038843

Description: glucosaminyl (N-acetyl) transferase 1, core 2

Associated with

Other Information

Genular Protein ID: 1154412690

Symbol: GCNT1_MOUSE

Name: Beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase

UniProtKB Accession Codes:

Q09324 O35981 Q8BRB2

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 BRENDA 1 Bgee 1 BioGRID-ORCS 1 CAZy 1 CCDS 1 CTD 1 ChEBI 39 ChiTaRS 1 DNASU 1 EC 2 EMBL 4 EPD 1 Ensembl 4 EvolutionaryTrace 1 GO 14 GeneTree 1 Genevisible 1 GlyCosmos 1 GlyGen 1 HOGENOM 1 InParanoid 1 InterPro 1 KEGG 1 MGI 1 MaxQB 1 NCBI Taxonomy 1 OMA 1 OrthoDB 1 PANTHER 2 PDB 7 PDBsum 3 PRO 1 PaxDb 1 Pfam 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 1 RNAct 1 Reactome 1 RefSeq 3 Rhea 12 SMR 1 STRING 1 UCSC 1 UniPathway 1 UniProtKB 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1

Citations:

PubMed ID: 9341170

Title: Tissue-specific regulation of mouse core 2 beta-1,6-N-acetylglucosaminyltransferase.

PubMed ID: 9341170

DOI: 10.1074/jbc.272.43.27246

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 7983056

Title: Purification and characterization of UDP-GlcNAc:IV3 beta Gal-Gb4Cer beta-1,6-GlcNAc transferase from mouse kidney.

PubMed ID: 7983056

DOI: 10.1016/s0021-9258(18)47401-7

PubMed ID: 9881978

Title: Core 2 oligosaccharide biosynthesis distinguishes between selectin ligands essential for leukocyte homing and inflammation.

PubMed ID: 9881978

DOI: 10.1016/s1074-7613(00)80653-6

PubMed ID: 12954635

Title: Highly conserved cysteines of mouse core 2 beta1,6-N-acetylglucosaminyltransferase I form a network of disulfide bonds and include a thiol that affects enzyme activity.

PubMed ID: 12954635

DOI: 10.1074/jbc.m303851200

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

PubMed ID: 16829524

Title: X-ray crystal structure of leukocyte type core 2 beta1,6-N-acetylglucosaminyltransferase. Evidence for a convergence of metal ion-independent glycosyltransferase mechanism.

PubMed ID: 16829524

DOI: 10.1074/jbc.m603534200

PubMed ID: 22056345

Title: Structural and mechanistic characterization of leukocyte-type core 2 beta1,6-N-acetylglucosaminyltransferase: a metal-ion-independent GT-A glycosyltransferase.

PubMed ID: 22056345

DOI: 10.1016/j.jmb.2011.10.039

Sequence Information:

  • Length: 428
  • Mass: 49839
  • Checksum: 57E54F07AFFE640B
  • Sequence:
    • MLRNLFRRRL FSCPTKYYFM LLVLSLITFS VLRIHQKPEF FSVRHLELAG DDPYSNVNCT 
KILQGDPEEI QKVKLEILTV QFKKRPRRTP HDYINMTRDC ASFIRTRKYI VEPLTKEEVG 
FPIAYSIVVH HKIEMLDRLL RAIYMPQNFY CIHVDRKAEE SFLAAVQGIA SCFDNVFVAS 
QLESVVYASW SRVKADLNCM KDLYRMNANW KYLINLCGMD FPIKTNLEIV RKLKCSTGEN 
NLETEKMPPN KEERWKKRYT VVDGKLTNTG IVKAPPPLKT PLFSGSAYFV VTREYVGYVL 
ENENIQKLME WAQDTYSPDE FLWATIQRIP EVPGSFPSSN KYDLSDMNAI ARFVKWQYFE 
GHVSNGAPYP PCSGVHVRSV CVFGAGDLSW MLRQHHLFAN KFDMDVDPFA IQCLDEHLRH 
KALENLEH

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.