Details for: Gdf11

Gene ID: 14561

Symbol: Gdf11

Ensembl ID: ENSMUSG00000025352

Description: growth differentiation factor 11

Associated with

Other Information

Genular Protein ID: 1440459106

Symbol: GDF11_MOUSE

Name: Growth/differentiation factor 11

UniProtKB Accession Codes:

Q9Z1W4 Q9QX55 Q9R221

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 CCDS 1 CDD 1 CTD 1 DIP 1 DNASU 1 EMBL 7 Ensembl 1 GO 23 Gene3D 2 GeneTree 1 GlyCosmos 1 GlyGen 1 HOGENOM 1 InParanoid 1 IntAct 1 InterPro 5 KEGG 1 MGI 1 MINT 1 NCBI Taxonomy 1 OMA 1 OrthoDB 1 PANTHER 2 PRO 1 PROSITE 2 PaxDb 1 PeptideAtlas 1 Pfam 2 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 1 RNAct 1 RefSeq 1 SMART 1 SMR 1 STRING 1 SUPFAM 1 TreeFam 1 UCSC 1 UniProtKB 1 VEuPathDB 1 eggNOG 1 iPTMnet 1

Citations:

PubMed ID: 10075854

Title: A novel BMP expressed in developing mouse limb, spinal cord, and tail bud is a potent mesoderm inducer in Xenopus embryos.

PubMed ID: 10075854

DOI: 10.1006/dbio.1998.9191

PubMed ID: 10391213

Title: Regulation of anterior/posterior patterning of the axial skeleton by growth/differentiation factor 11.

PubMed ID: 10391213

DOI: 10.1038/10320

PubMed ID: 10072786

Title: Expression of growth/differentiation factor 11, a new member of the BMP/TGFbeta superfamily during mouse embryogenesis.

PubMed ID: 10072786

DOI: 10.1016/s0925-4773(98)00205-6

PubMed ID: 15988002

Title: GDF11 forms a bone morphogenetic protein 1-activated latent complex that can modulate nerve growth factor-induced differentiation of PC12 cells.

PubMed ID: 15988002

DOI: 10.1128/mcb.25.14.5846-5858.2005

PubMed ID: 12414726

Title: Activin type IIA and IIB receptors mediate Gdf11 signaling in axial vertebral patterning.

PubMed ID: 12414726

DOI: 10.1101/gad.1021802

PubMed ID: 16845371

Title: Growth differentiation factor 11 signals through the transforming growth factor-beta receptor ALK5 to regionalize the anterior-posterior axis.

PubMed ID: 16845371

DOI: 10.1038/sj.embor.7400752

Sequence Information:

  • Length: 405
  • Mass: 44947
  • Checksum: A74E382710A14781
  • Sequence:
    • MVLAAPLLLG FLLLALELRP RGEAAEGPAA AAAAAAAAAG VGGERSSRPA PSAPPEPDGC 
PVCVWRQHSR ELRLESIKSQ ILSKLRLKEA PNISREVVKQ LLPKAPPLQQ ILDLHDFQGD 
ALQPEDFLEE DEYHATTETV ISMAQETDPA VQTDGSPLCC HFHFSPKVMF TKVLKAQLWV 
YLRPVPRPAT VYLQILRLKP LTGEGTAGGG GGGRRHIRIR SLKIELHSRS GHWQSIDFKQ 
VLHSWFRQPQ SNWGIEINAF DPSGTDLAVT SLGPGAEGLH PFMELRVLEN TKRSRRNLGL 
DCDEHSSESR CCRYPLTVDF EAFGWDWIIA PKRYKANYCS GQCEYMFMQK YPHTHLVQQA 
NPRGSAGPCC TPTKMSPINM LYFNDKQQII YGKIPGMVVD RCGCS

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.