Genular: Defining Cellular Identity and Function

Details for: Ggt1

Gene ID: 14598

Symbol: Ggt1

Ensembl ID: ENSMUSG00000006345

Description: gamma-glutamyltransferase 1

Associated with

Aflatoxin activation and detoxification
(R-MMU-5423646)
Arachidonic acid metabolism
(R-MMU-2142753)
Biological oxidations
(R-MMU-211859)
Drug adme
(R-MMU-9748784)
Fatty acid metabolism
(R-MMU-8978868)
Glutathione conjugation
(R-MMU-156590)
Glutathione synthesis and recycling
(R-MMU-174403)
Metabolism
(R-MMU-1430728)
Metabolism of lipids
(R-MMU-556833)
Paracetamol adme
(R-MMU-9753281)
Phase ii - conjugation of compounds
(R-MMU-156580)
Synthesis of leukotrienes (lt) and eoxins (ex)
(R-MMU-2142691)
Acyltransferase activity
(GO:0016746)
Aminoacyltransferase activity
(GO:0016755)
Cysteine biosynthetic process
(GO:0019344)
Endoplasmic reticulum
(GO:0005783)
Extracellular space
(GO:0005615)
Glutathione biosynthetic process
(GO:0006750)
Glutathione catabolic process
(GO:0006751)
Glutathione hydrolase activity
(GO:0036374)
Glutathione metabolic process
(GO:0006749)
Hydrolase activity
(GO:0016787)
Leukotriene-c(4) hydrolase
(GO:0002951)
Leukotriene c4 gamma-glutamyl transferase activity
(GO:0103068)
Membrane
(GO:0016020)
Peptidase activity
(GO:0008233)
Peptide modification
(GO:0031179)
Peptidyltransferase activity
(GO:0000048)
Perinuclear region of cytoplasm
(GO:0048471)
Plasma membrane
(GO:0005886)
Proteolysis
(GO:0006508)
Regulation of immune system process
(GO:0002682)
Regulation of inflammatory response
(GO:0050727)
Spermatogenesis
(GO:0007283)
Transferase activity
(GO:0016740)
Vesicle
(GO:0031982)

Other Information

Proteins

Glutathione hydrolase 1 proenzyme

Genular Protein ID: 673789173

Symbol: GGT1_MOUSE

Name: Glutathione hydrolase 1 proenzyme

UniProtKB Accession Codes:

Q60928

Database IDs:

Citations:

PubMed ID: 8566783

Title: Cloning of cDNA and genomic structure of the mouse gamma-glutamyl transpeptidase-encoding gene.

PubMed ID: 8566783

DOI: 10.1016/0378-1119(95)00618-4

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 8755578

Title: Growth retardation and cysteine deficiency in gamma-glutamyl transpeptidase-deficient mice.

PubMed ID: 8755578

DOI: 10.1073/pnas.93.15.7923

PubMed ID: 10392451

Title: Gamma-glutamyl transpeptidase gene organization and expression: a comparative analysis in rat, mouse, pig and human species.

PubMed ID: 10392451

DOI: 10.1016/s0305-0491(99)00013-9

PubMed ID: 9139708

Title: Mice with genetic gamma-glutamyl transpeptidase deficiency exhibit glutathionuria, severe growth failure, reduced life spans, and infertility.

PubMed ID: 9139708

DOI: 10.1074/jbc.272.19.12560

PubMed ID: 12810527

Title: Reversible skeletal abnormalities in gamma-glutamyl transpeptidase-deficient mice.

PubMed ID: 12810527

DOI: 10.1210/en.2002-0071

PubMed ID: 19349973

Title: Mass-spectrometric identification and relative quantification of N-linked cell surface glycoproteins.

PubMed ID: 19349973

DOI: 10.1038/nbt.1532

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

Sequence Information:

Length: 568
Mass: 61563
Checksum: 293C6E224FDC0766
Sequence:

MKNRFLVLGL VAVVLVFVII GLCIWLPYTS GKPDHVYSRA AVATDAKRCS EIGRDILQEG 
GSVVDAAIAS LLCMGLMNAH SMGIGGGLFF TIYNSTTGKV EVINAREVAP RLANTTMFNN 
SKDSEEGGLS VAVPGEIRGY ELAHQRHGRL PWARLFQPSI QLARHGFPVG KGLAIALDKK 
RDVIEKTPAL CEVFCRQGKV LQEGETVTMP KLADTLQILA QEGAKAFYNG SLTAQIVKDI 
QEAGGIMTVE DLNNYRAELI EHPMSIGLGD ATLYVPSAPL SGPVLILILN ILKGYNFSPK 
SVATPEQKAL TYHRIVEAFR FAYAKRTMLG DPKFVDVSQV IRNMSSEFYA TQLRARITDE 
TTHPAAYYEP EFYLQDDGGT AHLSAVSEDG SAVAATSTIN LYFGSKVLSR VSGILFNDEM 
DDFSSPNFIN QFRVAPSPAN FIKPGKQPLS SMCPSIILDK DGQVRMVVGA SGGTQITTSV 
ALAIINSLWF GYDVKRAVEE PRLHNQLLPN TTTVEKDIDQ VVTAGLKIRH HHTEVTPTFI 
AVVQAVVRAS GGWAAASDSR KGGEPAGY

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Ggt1

Associated with

Other Information

Cloning of cDNA and genomic structure of the mouse gamma-glutamyl transpeptidase-encoding gene. PubMed ID: 8566783

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Growth retardation and cysteine deficiency in gamma-glutamyl transpeptidase-deficient mice. PubMed ID: 8755578

Gamma-glutamyl transpeptidase gene organization and expression: a comparative analysis in rat, mouse, pig and human species. PubMed ID: 10392451

Mice with genetic gamma-glutamyl transpeptidase deficiency exhibit glutathionuria, severe growth failure, reduced life spans, and infertility. PubMed ID: 9139708

Reversible skeletal abnormalities in gamma-glutamyl transpeptidase-deficient mice. PubMed ID: 12810527

Mass-spectrometric identification and relative quantification of N-linked cell surface glycoproteins. PubMed ID: 19349973

A tissue-specific atlas of mouse protein phosphorylation and expression. PubMed ID: 21183079