Details for: CSNK2B

Gene ID: 1460

Symbol: CSNK2B

Ensembl ID: ENSG00000204435

Description: casein kinase 2 beta

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 344.2086
    Cell Significance Index: -53.5400
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 193.0269
    Cell Significance Index: -48.9600
  • Cell Name: embryonic stem cell (CL0002322)
    Fold Change: 151.7547
    Cell Significance Index: -62.5200
  • Cell Name: smooth muscle fiber of ileum (CL1000278)
    Fold Change: 150.4906
    Cell Significance Index: -71.0500
  • Cell Name: peripheral blood mononuclear cell (CL2000001)
    Fold Change: 131.4190
    Cell Significance Index: -67.6000
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 52.6134
    Cell Significance Index: -64.8700
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 17.4200
    Cell Significance Index: -68.7400
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 17.3208
    Cell Significance Index: -46.4000
  • Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
    Fold Change: 15.5529
    Cell Significance Index: -47.7700
  • Cell Name: kidney cell (CL1000497)
    Fold Change: 5.2566
    Cell Significance Index: 41.9700
  • Cell Name: fibroblast of dermis (CL0002551)
    Fold Change: 3.1679
    Cell Significance Index: 66.3100
  • Cell Name: skeletal muscle myoblast (CL0000515)
    Fold Change: 3.0962
    Cell Significance Index: 33.6600
  • Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
    Fold Change: 2.9438
    Cell Significance Index: 86.4600
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 2.4160
    Cell Significance Index: 392.9500
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: 2.3248
    Cell Significance Index: 149.9900
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 1.9933
    Cell Significance Index: 273.7300
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: 1.6669
    Cell Significance Index: 124.2300
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 1.5177
    Cell Significance Index: 671.0100
  • Cell Name: lactocyte (CL0002325)
    Fold Change: 1.5026
    Cell Significance Index: 194.1300
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: 1.4887
    Cell Significance Index: 69.4100
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: 1.4791
    Cell Significance Index: 69.5200
  • Cell Name: endothelial cell of venule (CL1000414)
    Fold Change: 1.4225
    Cell Significance Index: 16.1600
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: 1.4132
    Cell Significance Index: 99.9500
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: 1.3876
    Cell Significance Index: 48.2200
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 1.3025
    Cell Significance Index: 160.1500
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 1.2345
    Cell Significance Index: 674.1900
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 1.1946
    Cell Significance Index: 215.3400
  • Cell Name: odontoblast (CL0000060)
    Fold Change: 1.1916
    Cell Significance Index: 152.7600
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: 1.1691
    Cell Significance Index: 61.3800
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: 1.1128
    Cell Significance Index: 30.2900
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: 0.8802
    Cell Significance Index: 23.1500
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 0.7793
    Cell Significance Index: 40.4800
  • Cell Name: vascular lymphangioblast (CL0005022)
    Fold Change: 0.7659
    Cell Significance Index: 13.5400
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.7138
    Cell Significance Index: 70.6100
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: 0.6421
    Cell Significance Index: 13.9100
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 0.6280
    Cell Significance Index: 43.4300
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: 0.6141
    Cell Significance Index: 36.8700
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: 0.5551
    Cell Significance Index: 65.4700
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: 0.5124
    Cell Significance Index: 87.4900
  • Cell Name: peg cell (CL4033014)
    Fold Change: 0.3876
    Cell Significance Index: 8.9600
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.3415
    Cell Significance Index: 9.8400
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.2979
    Cell Significance Index: 56.6900
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: 0.2575
    Cell Significance Index: 7.3800
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 0.2350
    Cell Significance Index: 10.6500
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.2132
    Cell Significance Index: 192.4800
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: 0.2099
    Cell Significance Index: 13.2300
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 0.1815
    Cell Significance Index: 36.4100
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: 0.0918
    Cell Significance Index: 2.9400
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: 0.0768
    Cell Significance Index: 1.2900
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: 0.0698
    Cell Significance Index: 52.8700
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 0.0544
    Cell Significance Index: 19.5300
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: 0.0195
    Cell Significance Index: 0.5200
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: 0.0066
    Cell Significance Index: 4.8400
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0171
    Cell Significance Index: -12.6500
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: -0.0291
    Cell Significance Index: -54.8700
  • Cell Name: fibro/adipogenic progenitor cell (CL0009099)
    Fold Change: -0.0406
    Cell Significance Index: -2.0500
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0418
    Cell Significance Index: -26.0800
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: -0.0430
    Cell Significance Index: -1.5100
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: -0.0450
    Cell Significance Index: -82.9000
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: -0.0545
    Cell Significance Index: -83.8400
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: -0.0630
    Cell Significance Index: -85.6400
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0898
    Cell Significance Index: -50.6500
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.0918
    Cell Significance Index: -9.3800
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.0925
    Cell Significance Index: -10.6000
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: -0.0956
    Cell Significance Index: -60.7300
  • Cell Name: umbrella cell of urothelium (CL4030056)
    Fold Change: -0.0972
    Cell Significance Index: -0.9000
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.1432
    Cell Significance Index: -65.0100
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.1702
    Cell Significance Index: -35.8400
  • Cell Name: neuron associated cell (CL0000095)
    Fold Change: -0.2205
    Cell Significance Index: -9.0400
  • Cell Name: pro-T cell (CL0000827)
    Fold Change: -0.2953
    Cell Significance Index: -7.5500
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: -0.3255
    Cell Significance Index: -64.5900
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.3388
    Cell Significance Index: -39.4800
  • Cell Name: pancreatic endocrine cell (CL0008024)
    Fold Change: -0.4186
    Cell Significance Index: -47.7800
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.4209
    Cell Significance Index: -61.1800
  • Cell Name: paneth cell of colon (CL0009009)
    Fold Change: -0.4371
    Cell Significance Index: -6.5500
  • Cell Name: intestinal epithelial cell (CL0002563)
    Fold Change: -0.4661
    Cell Significance Index: -4.8300
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.5813
    Cell Significance Index: -46.0400
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: -0.6198
    Cell Significance Index: -17.3200
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: -0.6545
    Cell Significance Index: -13.9400
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.6686
    Cell Significance Index: -69.6200
  • Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
    Fold Change: -0.6747
    Cell Significance Index: -12.4700
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: -0.7933
    Cell Significance Index: -44.5200
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: -0.8111
    Cell Significance Index: -62.2400
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: -1.0408
    Cell Significance Index: -14.2000
  • Cell Name: kidney epithelial cell (CL0002518)
    Fold Change: -1.1051
    Cell Significance Index: -32.5500
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -1.1351
    Cell Significance Index: -69.5900
  • Cell Name: endothelial cell of placenta (CL0009092)
    Fold Change: -1.2298
    Cell Significance Index: -7.4300
  • Cell Name: microcirculation associated smooth muscle cell (CL0008035)
    Fold Change: -1.2643
    Cell Significance Index: -10.6200
  • Cell Name: stratified epithelial cell (CL0000079)
    Fold Change: -1.2874
    Cell Significance Index: -47.2600
  • Cell Name: luminal hormone-sensing cell of mammary gland (CL4033058)
    Fold Change: -1.3349
    Cell Significance Index: -8.2200
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: -1.4363
    Cell Significance Index: -63.5300
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: -1.5423
    Cell Significance Index: -54.0300
  • Cell Name: CD4-positive, alpha-beta thymocyte (CL0000810)
    Fold Change: -1.5471
    Cell Significance Index: -26.6700
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: -1.5569
    Cell Significance Index: -40.0200
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -1.6662
    Cell Significance Index: -54.5500
  • Cell Name: keratinocyte (CL0000312)
    Fold Change: -1.6748
    Cell Significance Index: -41.8300
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: -1.6933
    Cell Significance Index: -64.1200
  • Cell Name: extravillous trophoblast (CL0008036)
    Fold Change: -1.7366
    Cell Significance Index: -10.7900
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -1.7674
    Cell Significance Index: -56.2900
  • Cell Name: theca cell (CL0000503)
    Fold Change: -1.8128
    Cell Significance Index: -10.6500

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics** 1. **Casein Kinase 2 (CK2)**: The CSNK2B gene is part of the Casein Kinase 2 family, which is a serine/threonine kinase involved in various cellular processes. 2. **Dual-Specificity Kinase**: The CSNK2B protein exhibits dual-specificity kinase activity, allowing it to phosphorylate both serine and threonine residues on target proteins. 3. **Phosphorylation Reactions**: The CSNK2B enzyme is involved in a wide range of phosphorylation reactions, including the phosphorylation of transcription factors, signaling molecules, and structural proteins. 4. **Cellular Localization**: The CSNK2B protein is primarily localized to the cytosol and nucleus, where it regulates various cellular processes. **Pathways and Functions** 1. **Cell Cycle Regulation**: CSNK2B plays a crucial role in regulating the cell cycle, particularly in the G2/M phase, by phosphorylating key proteins involved in cell cycle progression. 2. **Apoptosis**: The CSNK2B protein is involved in regulating apoptosis by phosphorylating pro-apoptotic proteins and modulating the activity of anti-apoptotic proteins. 3. **Immune Response**: CSNK2B is expressed in immune cells and plays a role in regulating immune responses, including the activation of T cells and the regulation of cytokine production. 4. **Protein Folding**: The CSNK2B enzyme is involved in protein folding, particularly in the context of chaperone-mediated protein folding. 5. **Transcriptional Regulation**: CSNK2B regulates transcriptional activity by phosphorylating transcription factors and modulating the activity of RNA polymerase II. **Clinical Significance** 1. **Cancer Research**: The CSNK2B gene has been implicated in various cancers, including breast, lung, and colon cancer, where it is often overexpressed or mutated. 2. **Neurological Disorders**: CSNK2B has been linked to various neurological disorders, including Alzheimer's disease, Parkinson's disease, and amyotrophic lateral sclerosis (ALS). 3. **Immunological Disorders**: The CSNK2B protein is involved in regulating immune responses, and dysregulation of this gene has been implicated in autoimmune diseases, such as rheumatoid arthritis and multiple sclerosis. 4. **Infectious Diseases**: CSNK2B has been shown to play a role in regulating the replication of viruses, such as the respiratory syncytial virus (RSV). 5. **Developmental Biology**: The CSNK2B gene is involved in regulating developmental processes, including embryonic development and tissue homeostasis. In conclusion, the CSNK2B gene plays a critical role in regulating various cellular processes, including cell cycle progression, apoptosis, immune responses, protein folding, and transcriptional regulation. Its dysregulation has been implicated in various diseases, including cancer, neurological disorders, and immunological disorders, highlighting the importance of this gene in maintaining tissue homeostasis.

Genular Protein ID: 2593636872

Symbol: CSK2B_HUMAN

Name: Casein kinase II subunit beta

UniProtKB Accession Codes:

P67870 B0UXA9 P07312 P13862 Q4VX47

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BindingDB 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 1 CORUM 1 CTD 1 ChEBI 4 ChEMBL 1 ChiTaRS 1 ComplexPortal 3 DIP 1 DMDM 1 DNASU 1 DisGeNET 1 DrugBank 2 EMBL 20 Ensembl 21 EvolutionaryTrace 1 ExpressionAtlas 1 GO 34 Gene3D 2 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyGen 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 3 KEGG 1 MANE-Select 1 MIM 3 MINT 1 MalaCards 1 MassIVE 1 MetOSite 1 MoonDB 1 NCBI Taxonomy 1 OpenTargets 1 Orphanet 1 OrthoDB 1 PANTHER 2 PDB 10 PDBsum 10 PIR 1 PRINTS 1 PRO 1 PROSITE 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 1 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 1 Pumba 1 RNAct 1 Reactome 12 RefSeq 2 SIGNOR 1 SMART 1 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 SwissPalm 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 2666134

Title: Human phosvitin/casein kinase type II. Molecular cloning and sequencing of full-length cDNA encoding subunit beta.

PubMed ID: 2666134

DOI: 10.1111/j.1432-1033.1989.tb14917.x

PubMed ID: 1694965

Title: Expression of the cDNA for the beta subunit of human casein kinase II confers partial UV resistance on xeroderma pigmentosum cells.

PubMed ID: 1694965

DOI: 10.1016/0921-8777(90)90036-5

PubMed ID: 2513884

Title: Cloning and characterization of a cDNA encoding the beta subunit of human casein kinase II.

PubMed ID: 2513884

DOI: 10.1021/bi00449a014

PubMed ID: 1856204

Title: Structure of the gene encoding human casein kinase II subunit beta.

PubMed ID: 1856204

DOI: 10.1016/s0021-9258(18)92756-0

PubMed ID: 12102635

Title: Sequencing of full-length cDNA encoding the alpha and beta subunits of human casein kinase II from human platelets and megakaryocytic cells. Expression of the casein kinase IIalpha intronless gene in a megakaryocytic cell line.

PubMed ID: 12102635

DOI: 10.1021/bi025791r

PubMed ID: 14656967

Title: Analysis of the gene-dense major histocompatibility complex class III region and its comparison to mouse.

PubMed ID: 14656967

DOI: 10.1101/gr.1736803

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 14574404

Title: The DNA sequence and analysis of human chromosome 6.

PubMed ID: 14574404

DOI: 10.1038/nature02055

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 2300566

Title: Stimulation of casein kinase II by epidermal growth factor: relationship between the physiological activity of the kinase and the phosphorylation state of its beta subunit.

PubMed ID: 2300566

DOI: 10.1073/pnas.87.2.821

PubMed ID: 11298324

Title: Interaction of CD163 with the regulatory subunit of casein kinase II (CKII) and dependence of CD163 signaling on CKII and protein kinase C.

PubMed ID: 11298324

DOI: 10.1002/1521-4141(200104)31:4<999::aid-immu999>3.0.co;2-r

PubMed ID: 11239457

Title: A DNA damage-induced p53 serine 392 kinase complex contains CK2, hSpt16, and SSRP1.

PubMed ID: 11239457

DOI: 10.1016/s1097-2765(01)00176-9

PubMed ID: 11964394

Title: Identification of ribosome-binding protein p34 as an intracellular protein that binds acidic fibroblast growth factor.

PubMed ID: 11964394

DOI: 10.1074/jbc.m112193200

PubMed ID: 12393879

Title: p53 serine 392 phosphorylation increases after UV through induction of the assembly of the CK2.hSPT16.SSRP1 complex.

PubMed ID: 12393879

DOI: 10.1074/jbc.m209820200

PubMed ID: 17081983

Title: Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.

PubMed ID: 17081983

DOI: 10.1016/j.cell.2006.09.026

PubMed ID: 16818610

Title: Casein kinase 2-dependent serine phosphorylation of MuSK regulates acetylcholine receptor aggregation at the neuromuscular junction.

PubMed ID: 16818610

DOI: 10.1101/gad.375206

PubMed ID: 18691976

Title: Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle.

PubMed ID: 18691976

DOI: 10.1016/j.molcel.2008.07.007

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 19369195

Title: Large-scale proteomics analysis of the human kinome.

PubMed ID: 19369195

DOI: 10.1074/mcp.m800588-mcp200

PubMed ID: 19608861

Title: Lysine acetylation targets protein complexes and co-regulates major cellular functions.

PubMed ID: 19608861

DOI: 10.1126/science.1175371

PubMed ID: 20719947

Title: Epstein-Barr virus nuclear antigen 1 Hijacks the host kinase CK2 to disrupt PML nuclear bodies.

PubMed ID: 20719947

DOI: 10.1128/jvi.01183-10

PubMed ID: 20068231

Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.

PubMed ID: 20068231

DOI: 10.1126/scisignal.2000475

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 21406692

Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.

PubMed ID: 21406692

DOI: 10.1126/scisignal.2001570

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 24216761

Title: Identification of a novel protein interaction motif in the regulatory subunit of casein kinase 2.

PubMed ID: 24216761

DOI: 10.1128/mcb.00968-13

PubMed ID: 25755297

Title: System-wide analysis of SUMOylation dynamics in response to replication stress reveals novel small ubiquitin-like modified target proteins and acceptor lysines relevant for genome stability.

PubMed ID: 25755297

DOI: 10.1074/mcp.o114.044792

PubMed ID: 25944712

Title: N-terminome analysis of the human mitochondrial proteome.

PubMed ID: 25944712

DOI: 10.1002/pmic.201400617

PubMed ID: 28585349

Title: CSNK2B splice site mutations in patients cause intellectual disability with or without myoclonic epilepsy.

PubMed ID: 28585349

DOI: 10.1002/humu.23270

PubMed ID: 31341047

Title: Identification of ARKL1 as a Negative Regulator of Epstein-Barr Virus Reactivation.

PubMed ID: 31341047

DOI: 10.1128/jvi.00989-19

PubMed ID: 31784560

Title: Germline de novo variants in CSNK2B in Chinese patients with epilepsy.

PubMed ID: 31784560

DOI: 10.1038/s41598-019-53484-9

PubMed ID: 10357806

Title: Crystal structure of the human protein kinase CK2 regulatory subunit reveals its zinc finger-mediated dimerization.

PubMed ID: 10357806

DOI: 10.1093/emboj/18.11.2930

PubMed ID: 11574463

Title: Crystal structure of human protein kinase CK2: insights into basic properties of the CK2 holoenzyme.

PubMed ID: 11574463

DOI: 10.1093/emboj/20.19.5320

Sequence Information:

  • Length: 215
  • Mass: 24942
  • Checksum: E465B1E699B0E0EC
  • Sequence:
    • MSSSEEVSWI SWFCGLRGNE FFCEVDEDYI QDKFNLTGLN EQVPHYRQAL DMILDLEPDE 
ELEDNPNQSD LIEQAAEMLY GLIHARYILT NRGIAQMLEK YQQGDFGYCP RVYCENQPML 
PIGLSDIPGE AMVKLYCPKC MDVYTPKSSR HHHTDGAYFG TGFPHMLFMV HPEYRPKRPA 
NQFVPRLYGF KIHPMAYQLQ LQAASNFKSP VKTIR

Genular Protein ID: 2188601111

Symbol: A0A1U9X7J2_HUMAN

Name: N/A

UniProtKB Accession Codes:

A0A1U9X7J2

Database IDs:

ARBA 2 AlphaFoldDB 1 CTD 1 DNASU 1 DisGeNET 1 EMBL 3 GO 3 Gene3D 2 InterPro 3 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PRINTS 1 PeptideAtlas 1 Pfam 1 RefSeq 1 RuleBase 1 SMART 1 SMR 1 SUPFAM 1

Sequence Information:

  • Length: 212
  • Mass: 24685
  • Checksum: C3831FA07067DCF5
  • Sequence:
    • MSSSEEVSWI SWFCGLRGNE FFCEVDEDYI QDKFNLTGLN EQVPHYRQAL DMILDLEPDE 
ELEDNPNQSD LIEQAAEMLY GLIHARYILT NRGIAQMLEK YQQGDFGYCP RVYCENQPML 
PIDIPGEAMV KLYCPKCMDV YTPKSSRHHH TDGAYFGTGF PHMLFMVHPE YRPKRPANQF 
VPRLYGFKIH PMAYQLQLQA ASNFKSPVKT IR

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.