Details for: Gja5

Gene ID: 14613

Symbol: Gja5

Ensembl ID: ENSMUSG00000057123

Description: gap junction protein, alpha 5

Associated with

  • Gap junction trafficking
    (R-MMU-190828)
  • Gap junction trafficking and regulation
    (R-MMU-157858)
  • Membrane trafficking
    (R-MMU-199991)
  • Vesicle-mediated transport
    (R-MMU-5653656)
  • Anchoring junction
    (GO:0070161)
  • Artery morphogenesis
    (GO:0048844)
  • Atrial cardiac muscle cell to av node cell communication by electrical coupling
    (GO:0086044)
  • Atrial septum development
    (GO:0003283)
  • Atrial septum morphogenesis
    (GO:0060413)
  • Atrial ventricular junction remodeling
    (GO:0003294)
  • Av node cell to bundle of his cell communication
    (GO:0086067)
  • Av node cell to bundle of his cell communication by electrical coupling
    (GO:0086053)
  • Blood vessel development
    (GO:0001568)
  • Blood vessel diameter maintenance
    (GO:0097746)
  • Bundle of his cell to purkinje myocyte communication by electrical coupling
    (GO:0086054)
  • Cardiac conduction
    (GO:0061337)
  • Cardiac conduction system development
    (GO:0003161)
  • Cell-cell signaling
    (GO:0007267)
  • Cell communication
    (GO:0007154)
  • Cell communication by chemical coupling
    (GO:0010643)
  • Cell communication by electrical coupling
    (GO:0010644)
  • Cell communication by electrical coupling involved in cardiac conduction
    (GO:0086064)
  • Cell communication involved in cardiac conduction
    (GO:0086065)
  • Cell projection
    (GO:0042995)
  • Connexin binding
    (GO:0071253)
  • Connexin complex
    (GO:0005922)
  • Disordered domain specific binding
    (GO:0097718)
  • Embryonic heart tube development
    (GO:0035050)
  • Embryonic limb morphogenesis
    (GO:0030326)
  • Foramen ovale closure
    (GO:0035922)
  • Gap junction
    (GO:0005921)
  • Gap junction assembly
    (GO:0016264)
  • Gap junction channel activity
    (GO:0005243)
  • Gap junction channel activity involved in atrial cardiac muscle cell-av node cell electrical coupling
    (GO:0086076)
  • Gap junction channel activity involved in av node cell-bundle of his cell electrical coupling
    (GO:0086077)
  • Gap junction channel activity involved in bundle of his cell-purkinje myocyte electrical coupling
    (GO:0086078)
  • Gap junction channel activity involved in cardiac conduction electrical coupling
    (GO:0086075)
  • Gap junction hemi-channel activity
    (GO:0055077)
  • Heart development
    (GO:0007507)
  • Intercalated disc
    (GO:0014704)
  • Membrane
    (GO:0016020)
  • Mitral valve development
    (GO:0003174)
  • Negative regulation of blood pressure
    (GO:0045776)
  • Negative regulation of glomerular filtration
    (GO:0003105)
  • Outflow tract morphogenesis
    (GO:0003151)
  • Plasma membrane
    (GO:0005886)
  • Positive regulation of cell communication by chemical coupling
    (GO:0010652)
  • Positive regulation of vasoconstriction
    (GO:0045907)
  • Potassium ion transport
    (GO:0006813)
  • Pulmonary valve formation
    (GO:0003193)
  • Regulation of atrial cardiac muscle cell action potential
    (GO:0098910)
  • Regulation of atrial cardiac muscle cell membrane depolarization
    (GO:0060371)
  • Regulation of av node cell action potential
    (GO:0098904)
  • Regulation of bundle of his cell action potential
    (GO:0098905)
  • Regulation of cardiac muscle contraction
    (GO:0055117)
  • Regulation of cell communication by electrical coupling
    (GO:0010649)
  • Regulation of heart rate by cardiac conduction
    (GO:0086091)
  • Regulation of membrane depolarization during cardiac muscle cell action potential
    (GO:1900825)
  • Regulation of purkinje myocyte action potential
    (GO:0098906)
  • Regulation of renin secretion into blood stream
    (GO:1900133)
  • Regulation of systemic arterial blood pressure
    (GO:0003073)
  • Regulation of ventricular cardiac muscle cell membrane depolarization
    (GO:0060373)
  • Regulation of ventricular cardiac muscle cell membrane repolarization
    (GO:0060307)
  • Renal system process involved in regulation of systemic arterial blood pressure
    (GO:0003071)
  • Sa node cell action potential
    (GO:0086015)
  • Septum primum development
    (GO:0003284)
  • Skeletal system development
    (GO:0001501)
  • Vasodilation
    (GO:0042311)
  • Vasomotion
    (GO:1990029)
  • Ventricular cardiac muscle cell action potential
    (GO:0086005)
  • Ventricular septum development
    (GO:0003281)
  • Ventricular septum morphogenesis
    (GO:0060412)

Other Information

Genular Protein ID: 2365396352

Symbol: CXA5_MOUSE

Name: Gap junction alpha-5 protein

UniProtKB Accession Codes:

Q01231

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CCDS 1 CTD 1 ChiTaRS 1 DNASU 1 DisProt 1 EMBL 2 Ensembl 1 ExpressionAtlas 1 GO 65 Gene3D 1 GeneTree 1 Genevisible 1 GlyGen 1 HOGENOM 1 InParanoid 1 InterPro 8 KEGG 1 MGI 1 MaxQB 1 NCBI Taxonomy 1 OMA 1 OrthoDB 1 PANTHER 2 PIR 1 PRINTS 2 PRO 1 PROSITE 2 PaxDb 1 Pfam 2 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 1 RNAct 1 Reactome 1 RefSeq 2 SAM 1 SMART 2 SMR 1 STRING 1 SUPFAM 1 TreeFam 1 UCSC 1 UniProtKB 1 VEuPathDB 1 eggNOG 1 iPTMnet 1

Citations:

PubMed ID: 1318884

Title: Molecular cloning and functional expression of mouse connexin40, a second gap junction gene preferentially expressed in lung.

PubMed ID: 1318884

DOI: 10.1083/jcb.117.6.1299

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 28179430

Title: Polydom Is an Extracellular Matrix Protein Involved in Lymphatic Vessel Remodeling.

PubMed ID: 28179430

DOI: 10.1161/circresaha.116.308825

Sequence Information:

  • Length: 358
  • Mass: 40413
  • Checksum: C5418F657142896A
  • Sequence:
    • MGDWSFLGEF LEEVHKHSTV IGKVWLTVLF IFRMLVLGTA AESSWGDEQA DFRCDTIQPG 
CQNVCYDQAF PISHIRYWVL QIIFVSTPSL VYMGHAMHTV RMQEKQKLRD AEKAKEAHRT 
GAYEYPVAEK AELSCWKEVD GKIVLQGTLL NTYVCTILIR TTMEVAFIVG QYLLYGIFLD 
TLHVCRRSPC PHPVNCYVSR PTEKNVFIVF MMAVAGLSLF LSLAELYHLG WKKIRQRFGK 
SRQGVDKHQL PGPPTSLVQS LTPPPDFNQC LKNSSGEKFF SDFSNNMGSR KNPDALATGE 
VPNQEQIPGE GFIHMHYSQK PEYASGASAG HRLPQGYHSD KRRLSKASSK ARSDDLSV

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.