Genular: Defining Cellular Identity and Function

Details for: Gclm

Gene ID: 14630

Symbol: Gclm

Ensembl ID: ENSMUSG00000028124

Description: glutamate-cysteine ligase, modifier subunit

Associated with

Biological oxidations
(R-MMU-211859)
Glutathione conjugation
(R-MMU-156590)
Glutathione synthesis and recycling
(R-MMU-174403)
Metabolism
(R-MMU-1430728)
Phase ii - conjugation of compounds
(R-MMU-156580)
Apoptotic mitochondrial changes
(GO:0008637)
Blood vessel diameter maintenance
(GO:0097746)
Cellular response to leukemia inhibitory factor
(GO:1990830)
Cysteine metabolic process
(GO:0006534)
Enzyme regulator activity
(GO:0030234)
Glutamate-cysteine ligase activity
(GO:0004357)
Glutamate-cysteine ligase catalytic subunit binding
(GO:0035226)
Glutamate-cysteine ligase complex
(GO:0017109)
Glutamate metabolic process
(GO:0006536)
Glutathione biosynthetic process
(GO:0006750)
Glutathione metabolic process
(GO:0006749)
Negative regulation of extrinsic apoptotic signaling pathway
(GO:2001237)
Negative regulation of neuron apoptotic process
(GO:0043524)
Positive regulation of glutamate-cysteine ligase activity
(GO:0035229)
Protein-containing complex binding
(GO:0044877)
Protein binding
(GO:0005515)
Regulation of mitochondrial depolarization
(GO:0051900)
Response to nitrosative stress
(GO:0051409)
Response to oxidative stress
(GO:0006979)
Response to xenobiotic stimulus
(GO:0009410)

Other Information

Proteins

Glutamate--cysteine ligase regulatory subunit

Genular Protein ID: 2104989894

Symbol: GSH0_MOUSE

Name: Glutamate--cysteine ligase regulatory subunit

UniProtKB Accession Codes:

O09172

Database IDs:

Citations:

PubMed ID: 9294003

Title: Molecular cloning and sequencing of the cDNA encoding mouse glutamate-cysteine ligase regulatory subunit.

PubMed ID: 9294003

DOI: 10.1016/s0167-4781(97)00092-4

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

Sequence Information:

Length: 274
Mass: 30535
Checksum: E1D591CAB71CEA11
Sequence:

MGTDSRAAGA LLARASTLHL QTGNLLNWGR LRKKCPSTHS EELRDCIQKT LNEWSSQISP 
DLVREFPDVL ECTMSHAVEK INPDEREEMK VSAKLFIVGS NSSSSTRSAV DMACSVLGVA 
QLDSVIMASP PIEDGVNLSL EHLQPYWEEL ENLVQSKKIV AIGTSDLDKT QLEQLYQWAQ 
VKPNSNQVNL ASCCVMPPDL TAFAKQFDIQ LLTHNDPKEL LSEASFQEAL QESIPDIEAQ 
DWVPLWLLRY SVIVKSRGII KSKGYILQAK RRGS

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.