Genular: Defining Cellular Identity and Function

Details for: Glp1r

Gene ID: 14652

Symbol: Glp1r

Ensembl ID: ENSMUSG00000024027

Description: glucagon-like peptide 1 receptor

Associated with

Class b/2 (secretin family receptors)
(R-MMU-373080)
G alpha (s) signalling events
(R-MMU-418555)
Glucagon-like peptide-1 (glp1) regulates insulin secretion
(R-MMU-381676)
Glucagon-type ligand receptors
(R-MMU-420092)
Gpcr downstream signalling
(R-MMU-388396)
Gpcr ligand binding
(R-MMU-500792)
Integration of energy metabolism
(R-MMU-163685)
Metabolism
(R-MMU-1430728)
Regulation of insulin secretion
(R-MMU-422356)
Signaling by gpcr
(R-MMU-372790)
Adenylate cyclase-activating g protein-coupled receptor signaling pathway
(GO:0007189)
Associative learning
(GO:0008306)
Camp-mediated signaling
(GO:0019933)
Cell surface receptor signaling pathway
(GO:0007166)
Feeding behavior
(GO:0007631)
Glucagon-like peptide 1 receptor activity
(GO:0044508)
Glucagon receptor activity
(GO:0004967)
G protein-coupled peptide receptor activity
(GO:0008528)
G protein-coupled receptor activity
(GO:0004930)
G protein-coupled receptor signaling pathway
(GO:0007186)
Hormone secretion
(GO:0046879)
Insulin secretion
(GO:0030073)
Learning or memory
(GO:0007611)
Membrane
(GO:0016020)
Memory
(GO:0007613)
Negative regulation of apoptotic process
(GO:0043066)
Negative regulation of blood pressure
(GO:0045776)
Negative regulation of neuron apoptotic process
(GO:0043524)
Neuropeptide signaling pathway
(GO:0007218)
Peptide hormone binding
(GO:0017046)
Peptide receptor activity
(GO:0001653)
Plasma membrane
(GO:0005886)
Positive regulation of blood pressure
(GO:0045777)
Positive regulation of cell differentiation
(GO:0045597)
Positive regulation of cell population proliferation
(GO:0008284)
Positive regulation of cytosolic calcium ion concentration
(GO:0007204)
Positive regulation of insulin secretion
(GO:0032024)
Positive regulation of transcription by rna polymerase ii
(GO:0045944)
Post-translational protein targeting to membrane, translocation
(GO:0031204)
Regulation of calcium ion transport
(GO:0051924)
Regulation of heart contraction
(GO:0008016)
Release of sequestered calcium ion into cytosol
(GO:0051209)
Response to glucose
(GO:0009749)
Response to psychosocial stress
(GO:1990911)
Signaling receptor activity
(GO:0038023)
Signal transduction
(GO:0007165)
Transmembrane signaling receptor activity
(GO:0004888)

Other Information

Proteins

Glucagon-like peptide 1 receptor

Genular Protein ID: 3074053864

Symbol: GLP1R_MOUSE

Name: Glucagon-like peptide 1 receptor

UniProtKB Accession Codes:

O35659 Q1JQR8

Database IDs:

Citations:

PubMed ID: 9568699

Title: Mouse pancreatic beta-cells exhibit preserved glucose competence after disruption of the glucagon-like peptide-1 receptor gene.

PubMed ID: 9568699

DOI: 10.2337/diabetes.47.4.646

PubMed ID: 16946080

Title: Quantitative trait loci for carbohydrate and total energy intake on mouse chromosome 17: congenic strain confirmation and candidate gene analyses (Glo1, Glp1r).

PubMed ID: 16946080

DOI: 10.1152/ajpregu.00491.2006

PubMed ID: 19468303

Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.

PubMed ID: 19468303

DOI: 10.1371/journal.pbio.1000112

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

Sequence Information:

Length: 463
Mass: 53028
Checksum: FBA3D9D79A30E9C3
Sequence:

MASTPSLLRL ALLLLGAVGR AGPRPQGTTV SLSETVQKWR EYRRQCQRFL TEAPLLATGL 
FCNRTFDDYA CWPDGPPGSF VNVSCPWYLP WASSVLQGHV YRFCTAEGLW LHKDNSSLPW 
RDLSECEESK RGERNFPEEQ LLSLYIIYTV GYALSFSALV IASAILVGFR HLHCTRNYIH 
LNLFASFILR ALSVFIKDAA LKWMYSTAAQ QHQWDGLLSY QDSLGCRLVF LLMQYCVAAN 
YYWLLVEGVY LYTLLAFSVF SEQRIFKLYL SIGWGVPLLF VIPWGIVKYL YEDEGCWTRN 
SNMNYWLIIR LPILFAIGVN FLIFIRVICI VVSKLKANLM CKTDIKCRLA KSTLTLIPLL 
GTHEVIFAFV MDEHARGTLR FIKLFTELSF TSFQGLMVAI LYCFVNNEVQ MEFRKCWERW 
RLEHLNIQRD CSMKPLKCPT SSVSSGATVG SSVYAATCQS SYS

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Glp1r

Associated with

Other Information

Mouse pancreatic beta-cells exhibit preserved glucose competence after disruption of the glucagon-like peptide-1 receptor gene. PubMed ID: 9568699

Quantitative trait loci for carbohydrate and total energy intake on mouse chromosome 17: congenic strain confirmation and candidate gene analyses (Glo1, Glp1r). PubMed ID: 16946080

Lineage-specific biology revealed by a finished genome assembly of the mouse. PubMed ID: 19468303

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Database document:

PubMed ID: 9568699

PubMed ID: 16946080

PubMed ID: 19468303

PubMed ID: 15489334