Genular: Defining Cellular Identity and Function

Details for: Gnai2

Gene ID: 14678

Symbol: Gnai2

Ensembl ID: ENSMUSG00000032562

Description: G protein subunit alpha i2

Associated with

Activation of gabab receptors
(R-MMU-991365)
Adenylate cyclase inhibitory pathway
(R-MMU-170670)
Adp signalling through p2y purinoceptor 12
(R-MMU-392170)
Adrenaline,noradrenaline inhibits insulin secretion
(R-MMU-400042)
Esr-mediated signaling
(R-MMU-8939211)
Extra-nuclear estrogen signaling
(R-MMU-9009391)
G-protein mediated events
(R-MMU-112040)
Gaba b receptor activation
(R-MMU-977444)
Gaba receptor activation
(R-MMU-977443)
G alpha (i) signalling events
(R-MMU-418594)
Gpcr downstream signalling
(R-MMU-388396)
Hemostasis
(R-MMU-109582)
Integration of energy metabolism
(R-MMU-163685)
Metabolism
(R-MMU-1430728)
Neuronal system
(R-MMU-112316)
Neurotransmitter receptors and postsynaptic signal transmission
(R-MMU-112314)
Opioid signalling
(R-MMU-111885)
Platelet activation, signaling and aggregation
(R-MMU-76002)
Regulation of insulin secretion
(R-MMU-422356)
Signal amplification
(R-MMU-392518)
Signaling by gpcr
(R-MMU-372790)
Signaling by nuclear receptors
(R-MMU-9006931)
Transmission across chemical synapses
(R-MMU-112315)
Adenylate cyclase-activating g protein-coupled receptor signaling pathway
(GO:0007189)
Adenylate cyclase-inhibiting g protein-coupled receptor signaling pathway
(GO:0007193)
Adenylate cyclase-modulating g protein-coupled receptor signaling pathway
(GO:0007188)
Cell body
(GO:0044297)
Cell cycle
(GO:0007049)
Cell division
(GO:0051301)
Cell population proliferation
(GO:0008283)
Centrosome
(GO:0005813)
Cytoplasm
(GO:0005737)
Cytoskeleton
(GO:0005856)
Cytosol
(GO:0005829)
Dendrite
(GO:0030425)
G-protein beta/gamma-subunit complex binding
(GO:0031683)
Gamma-aminobutyric acid signaling pathway
(GO:0007214)
G protein-coupled acetylcholine receptor signaling pathway
(GO:0007213)
G protein-coupled adenosine receptor signaling pathway
(GO:0001973)
G protein-coupled receptor binding
(GO:0001664)
G protein-coupled receptor signaling pathway
(GO:0007186)
Gtpase activity
(GO:0003924)
Gtp binding
(GO:0005525)
Guanyl nucleotide binding
(GO:0019001)
Heterotrimeric g-protein complex
(GO:0005834)
Membrane
(GO:0016020)
Metal ion binding
(GO:0046872)
Midbody
(GO:0030496)
Negative regulation of adenylate cyclase-activating adrenergic receptor signaling pathway involved in heart process
(GO:0140199)
Negative regulation of apoptotic signaling pathway
(GO:2001234)
Negative regulation of calcium ion-dependent exocytosis
(GO:0045955)
Negative regulation of synaptic transmission
(GO:0050805)
Neuronal dense core vesicle
(GO:0098992)
Nucleoplasm
(GO:0005654)
Nucleotide binding
(GO:0000166)
Plasma membrane
(GO:0005886)
Positive regulation of cell migration
(GO:0030335)
Positive regulation of cell population proliferation
(GO:0008284)
Positive regulation of erk1 and erk2 cascade
(GO:0070374)
Positive regulation of insulin receptor signaling pathway
(GO:0046628)
Positive regulation of neural precursor cell proliferation
(GO:2000179)
Positive regulation of superoxide anion generation
(GO:0032930)
Positive regulation of urine volume
(GO:0035810)
Positive regulation of vascular associated smooth muscle cell proliferation
(GO:1904707)
Protein binding
(GO:0005515)
Regulation of calcium ion transport
(GO:0051924)
Regulation of heart contraction
(GO:0008016)
Signal transduction
(GO:0007165)

Other Information

Proteins

Guanine nucleotide-binding protein G(i) subunit alpha-2

Genular Protein ID: 1447280177

Symbol: GNAI2_MOUSE

Name: Guanine nucleotide-binding protein G(i) subunit alpha-2

UniProtKB Accession Codes:

P08752 Q3TXK7 Q6P1C0

Database IDs:

Citations:

PubMed ID: 3092218

Title: Inhibitory and stimulatory G proteins of adenylate cyclase: cDNA and amino acid sequences of the alpha chains.

PubMed ID: 3092218

DOI: 10.1073/pnas.83.18.6687

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 8170357

Title: G protein Gi2 alpha in the cochlea: cloning and selective occurrence in receptor cells.

PubMed ID: 8170357

DOI: 10.1016/0169-328x(94)90267-4

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

Sequence Information:

Length: 355
Mass: 40489
Checksum: 90AC64AFA713493E
Sequence:

MGCTVSAEDK AAAERSKMID KNLREDGEKA AREVKLLLLG AGESGKSTIV KQMKIIHEDG 
YSEEECRQYR AVVYSNTIQS IMAIVKAMGN LQIDFADPQR ADDARQLFAL SCAAEEQGML 
PEDLSGVIRR LWADHGVQAC FGRSREYQLN DSAAYYLNDL ERIAQSDYIP TQQDVLRTRV 
KTTGIVETHF TFKDLHFKMF DVGGQRSERK KWIHCFEGVT AIIFCVALSA YDLVLAEDEE 
MNRMHESMKL FDSICNNKWF TDTSIILFLN KKDLFEEKIT QSSLTICFPE YTGANKYDEA 
ASYIQSKFED LNKRKDTKEI YTHFTCATDT KNVQFVFDAV TDVIIKNNLK DCGLF

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Gnai2

Associated with

Other Information

Inhibitory and stimulatory G proteins of adenylate cyclase: cDNA and amino acid sequences of the alpha chains. PubMed ID: 3092218

The transcriptional landscape of the mammalian genome. PubMed ID: 16141072

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334