ADRA1B | ENSG00000170214 | NCBI 147

Details for: ADRA1B

Gene ID: 147

Symbol: ADRA1B

Ensembl ID: ENSG00000170214

Description: adrenoceptor alpha 1B

Associated with

Adrenoceptors
(R-HSA-390696)
Amine ligand-binding receptors
(R-HSA-375280)
Class a/1 (rhodopsin-like receptors)
(R-HSA-373076)
G alpha (12/13) signalling events
(R-HSA-416482)
G alpha (q) signalling events
(R-HSA-416476)
Gpcr downstream signalling
(R-HSA-388396)
Gpcr ligand binding
(R-HSA-500792)
Signaling by gpcr
(R-HSA-372790)
Signal transduction
(R-HSA-162582)
Adenylate cyclase-activating adrenergic receptor signaling pathway
(GO:0071880)
Adenylate cyclase-modulating g protein-coupled receptor signaling pathway
(GO:0007188)
Alpha1-adrenergic receptor activity
(GO:0004937)
Caveola
(GO:0005901)
Cell-cell signaling
(GO:0007267)
Cytoplasm
(GO:0005737)
G protein-coupled receptor signaling pathway
(GO:0007186)
Intracellular signal transduction
(GO:0035556)
Neuron-glial cell signaling
(GO:0150099)
Nuclear membrane
(GO:0031965)
Nucleus
(GO:0005634)
Phospholipase c-activating g protein-coupled receptor signaling pathway
(GO:0007200)
Plasma membrane
(GO:0005886)
Positive regulation of cytosolic calcium ion concentration
(GO:0007204)
Positive regulation of heart rate by epinephrine-norepinephrine
(GO:0001996)
Positive regulation of mapk cascade
(GO:0043410)
Protein binding
(GO:0005515)
Protein heterodimerization activity
(GO:0046982)
Regulation of cardiac muscle contraction
(GO:0055117)
Regulation of vasoconstriction
(GO:0019229)

Other Information

Proteins

Alpha-1B adrenergic receptor

Genular Protein ID: 3379519419

Symbol: ADA1B_HUMAN

Name: Alpha-1B adrenergic receptor

UniProtKB Accession Codes:

P35368 B0LPE1

Database IDs:

Citations:

PubMed ID: 1328250

Title: Genomic organization and expression of the human alpha 1B-adrenergic receptor.

PubMed ID: 1328250

DOI: 10.1016/s0021-9258(19)36703-1

PubMed ID: 8183249

Title: The alpha 1-adrenergic receptor that mediates smooth muscle contraction in human prostate has the pharmacological properties of the cloned human alpha 1c subtype.

PubMed ID: 8183249

PubMed ID: 7815325

Title: Cloning and pharmacological characterization of human alpha-1 adrenergic receptors: sequence corrections and direct comparison with other species homologues.

PubMed ID: 7815325

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 18802028

Title: Nuclear alpha1-adrenergic receptors signal activated ERK localization to caveolae in adult cardiac myocytes.

PubMed ID: 18802028

DOI: 10.1161/circresaha.108.176024

PubMed ID: 22120526

Title: Nuclear localization drives alpha1-adrenergic receptor oligomerization and signaling in cardiac myocytes.

PubMed ID: 22120526

DOI: 10.1016/j.cellsig.2011.11.014

PubMed ID: 24567387

Title: MURC/Cavin-4 facilitates recruitment of ERK to caveolae and concentric cardiac hypertrophy induced by alpha1-adrenergic receptors.

PubMed ID: 24567387

DOI: 10.1073/pnas.1315359111

Sequence Information:

Length: 520
Mass: 56836
Checksum: F081A23D2F943F7F
Sequence:

MNPDLDTGHN TSAPAHWGEL KNANFTGPNQ TSSNSTLPQL DITRAISVGL VLGAFILFAI 
VGNILVILSV ACNRHLRTPT NYFIVNLAMA DLLLSFTVLP FSAALEVLGY WVLGRIFCDI 
WAAVDVLCCT ASILSLCAIS IDRYIGVRYS LQYPTLVTRR KAILALLSVW VLSTVISIGP 
LLGWKEPAPN DDKECGVTEE PFYALFSSLG SFYIPLAVIL VMYCRVYIVA KRTTKNLEAG 
VMKEMSNSKE LTLRIHSKNF HEDTLSSTKA KGHNPRSSIA VKLFKFSREK KAAKTLGIVV 
GMFILCWLPF FIALPLGSLF STLKPPDAVF KVVFWLGYFN SCLNPIIYPC SSKEFKRAFV 
RILGCQCRGR GRRRRRRRRR LGGCAYTYRP WTRGGSLERS QSRKDSLDDS GSCLSGSQRT 
LPSASPSPGY LGRGAPPPVE LCAFPEWKAP GALLSLPAPE PPGRRGRHDS GPLFTFKLLT 
EPESPGTDGG ASNGGCEAAA DVANGQPGFK SNMPLAPGQF

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: ADRA1B

Associated with

Other Information

Genomic organization and expression of the human alpha 1B-adrenergic receptor. PubMed ID: 1328250

The alpha 1-adrenergic receptor that mediates smooth muscle contraction in human prostate has the pharmacological properties of the cloned human alpha 1c subtype. PubMed ID: 8183249

Cloning and pharmacological characterization of human alpha-1 adrenergic receptors: sequence corrections and direct comparison with other species homologues. PubMed ID: 7815325

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Nuclear alpha1-adrenergic receptors signal activated ERK localization to caveolae in adult cardiac myocytes. PubMed ID: 18802028

Nuclear localization drives alpha1-adrenergic receptor oligomerization and signaling in cardiac myocytes. PubMed ID: 22120526

MURC/Cavin-4 facilitates recruitment of ERK to caveolae and concentric cardiac hypertrophy induced by alpha1-adrenergic receptors. PubMed ID: 24567387