Associated with
Cells (max top 100)
(Marker Score score is uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: early promyelocyte (CL0002154)
Fold Change: 5.11
Marker Score: 4087 - Cell Name: secretory cell (CL0000151)
Fold Change: 4.95
Marker Score: 9033 - Cell Name: mature astrocyte (CL0002627)
Fold Change: 4.62
Marker Score: 3038 - Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
Fold Change: 4.51
Marker Score: 252199 - Cell Name: foveolar cell of stomach (CL0002179)
Fold Change: 4.25
Marker Score: 27102 - Cell Name: fibroblast of connective tissue of nonglandular part of prostate (CL1000304)
Fold Change: 4.15
Marker Score: 3534 - Cell Name: acinar cell of salivary gland (CL0002623)
Fold Change: 4.11
Marker Score: 9373 - Cell Name: epithelial cell of lung (CL0000082)
Fold Change: 4.04
Marker Score: 21220 - Cell Name: skeletal muscle satellite stem cell (CL0008011)
Fold Change: 4.02
Marker Score: 4298 - Cell Name: kidney loop of Henle thick ascending limb epithelial cell (CL1001106)
Fold Change: 3.98
Marker Score: 10654 - Cell Name: lung macrophage (CL1001603)
Fold Change: 3.93
Marker Score: 4492 - Cell Name: endocrine cell (CL0000163)
Fold Change: 3.91
Marker Score: 2023 - Cell Name: acinar cell (CL0000622)
Fold Change: 3.9
Marker Score: 2753 - Cell Name: type I pneumocyte (CL0002062)
Fold Change: 3.82
Marker Score: 4607 - Cell Name: supporting cell (CL0000630)
Fold Change: 3.72
Marker Score: 6982 - Cell Name: mucous neck cell (CL0000651)
Fold Change: 3.67
Marker Score: 8317 - Cell Name: non-classical monocyte (CL0000875)
Fold Change: 3.64
Marker Score: 8791 - Cell Name: type G enteroendocrine cell (CL0000508)
Fold Change: 3.61
Marker Score: 1245 - Cell Name: colon epithelial cell (CL0011108)
Fold Change: 3.61
Marker Score: 11338.5 - Cell Name: type II pneumocyte (CL0002063)
Fold Change: 3.58
Marker Score: 23318 - Cell Name: fibroblast of lung (CL0002553)
Fold Change: 3.57
Marker Score: 9348 - Cell Name: epithelial cell (CL0000066)
Fold Change: 3.52
Marker Score: 5605.5 - Cell Name: basal cell of prostate epithelium (CL0002341)
Fold Change: 3.52
Marker Score: 8605 - Cell Name: kidney collecting duct principal cell (CL1001431)
Fold Change: 3.5
Marker Score: 8832 - Cell Name: myelocyte (CL0002193)
Fold Change: 3.5
Marker Score: 1512 - Cell Name: CD14-positive, CD16-positive monocyte (CL0002397)
Fold Change: 3.49
Marker Score: 6797 - Cell Name: intestine goblet cell (CL0019031)
Fold Change: 3.46
Marker Score: 3319 - Cell Name: fibroblast of mammary gland (CL0002555)
Fold Change: 3.45
Marker Score: 117497 - Cell Name: medullary thymic epithelial cell (CL0002365)
Fold Change: 3.42
Marker Score: 5605.5 - Cell Name: Sertoli cell (CL0000216)
Fold Change: 3.41
Marker Score: 20236 - Cell Name: lung secretory cell (CL1000272)
Fold Change: 3.41
Marker Score: 3039 - Cell Name: fibroblast of connective tissue of glandular part of prostate (CL1000305)
Fold Change: 3.4
Marker Score: 1415 - Cell Name: fibroblast (CL0000057)
Fold Change: 3.35
Marker Score: 3231 - Cell Name: bronchus fibroblast of lung (CL2000093)
Fold Change: 3.34
Marker Score: 4586 - Cell Name: mesothelial cell of epicardium (CL0011019)
Fold Change: 3.33
Marker Score: 1069 - Cell Name: peptic cell (CL0000155)
Fold Change: 3.32
Marker Score: 1390 - Cell Name: CD1c-positive myeloid dendritic cell (CL0002399)
Fold Change: 3.3
Marker Score: 8559 - Cell Name: epithelial cell of proximal tubule (CL0002306)
Fold Change: 3.3
Marker Score: 11715 - Cell Name: basal cell of epithelium of trachea (CL1000348)
Fold Change: 3.29
Marker Score: 24496 - Cell Name: serous secreting cell (CL0000313)
Fold Change: 3.29
Marker Score: 1312 - Cell Name: Kupffer cell (CL0000091)
Fold Change: 3.29
Marker Score: 3287.5 - Cell Name: enterocyte (CL0000584)
Fold Change: 3.26
Marker Score: 15667 - Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
Fold Change: 3.22
Marker Score: 12421 - Cell Name: tracheobronchial goblet cell (CL0019003)
Fold Change: 3.22
Marker Score: 882 - Cell Name: cell in vitro (CL0001034)
Fold Change: 3.21
Marker Score: 111088 - Cell Name: CD14-positive monocyte (CL0001054)
Fold Change: 3.21
Marker Score: 7987 - Cell Name: late promyelocyte (CL0002151)
Fold Change: 3.19
Marker Score: 801 - Cell Name: stratified epithelial cell (CL0000079)
Fold Change: 3.18
Marker Score: 24814.5 - Cell Name: inflammatory cell (CL0009002)
Fold Change: 3.17
Marker Score: 1363 - Cell Name: basophil (CL0000767)
Fold Change: 3.14
Marker Score: 1493 - Cell Name: ciliated columnar cell of tracheobronchial tree (CL0002145)
Fold Change: 3.14
Marker Score: 27243 - Cell Name: kidney loop of Henle thin ascending limb epithelial cell (CL1001107)
Fold Change: 3.13
Marker Score: 3176 - Cell Name: luminal cell of prostate epithelium (CL0002340)
Fold Change: 3.13
Marker Score: 1823 - Cell Name: endothelial cell of uterus (CL0009095)
Fold Change: 3.1
Marker Score: 6183 - Cell Name: epithelial cell of urethra (CL1000296)
Fold Change: 3.09
Marker Score: 2434 - Cell Name: kidney interstitial cell (CL1000500)
Fold Change: 3.06
Marker Score: 2176 - Cell Name: vascular lymphangioblast (CL0005022)
Fold Change: 3.03
Marker Score: 5126.5 - Cell Name: alveolar macrophage (CL0000583)
Fold Change: 3.03
Marker Score: 77546 - Cell Name: glandular cell of esophagus (CL0002657)
Fold Change: 3.02
Marker Score: 957 - Cell Name: club cell (CL0000158)
Fold Change: 3.02
Marker Score: 3523 - Cell Name: paneth cell (CL0000510)
Fold Change: 3.02
Marker Score: 2099 - Cell Name: kidney collecting duct intercalated cell (CL1001432)
Fold Change: 3.01
Marker Score: 4992 - Cell Name: uterine smooth muscle cell (CL0002601)
Fold Change: 3
Marker Score: 3905 - Cell Name: enteroendocrine cell (CL0000164)
Fold Change: 2.99
Marker Score: 1546 - Cell Name: rod bipolar cell (CL0000751)
Fold Change: 2.98
Marker Score: 1559 - Cell Name: reticular cell (CL0000432)
Fold Change: 2.97
Marker Score: 1083 - Cell Name: capillary endothelial cell (CL0002144)
Fold Change: 2.93
Marker Score: 3153 - Cell Name: stromal cell of ovary (CL0002132)
Fold Change: 2.92
Marker Score: 32924 - Cell Name: astrocyte (CL0000127)
Fold Change: 2.91
Marker Score: 2525 - Cell Name: decidual cell (CL2000002)
Fold Change: 2.91
Marker Score: 12547 - Cell Name: fibroblast of breast (CL4006000)
Fold Change: 2.88
Marker Score: 1644 - Cell Name: alternatively activated macrophage (CL0000890)
Fold Change: 2.87
Marker Score: 1197 - Cell Name: pneumocyte (CL0000322)
Fold Change: 2.87
Marker Score: 4607 - Cell Name: smooth muscle cell (CL0000192)
Fold Change: 2.86
Marker Score: 1884 - Cell Name: eurydendroid cell (CL0000253)
Fold Change: 2.84
Marker Score: 1161 - Cell Name: epithelial cell of esophagus (CL0002252)
Fold Change: 2.84
Marker Score: 24458 - Cell Name: duct epithelial cell (CL0000068)
Fold Change: 2.82
Marker Score: 1315 - Cell Name: eukaryotic cell (CL0000255)
Fold Change: 2.81
Marker Score: 1446 - Cell Name: kidney distal convoluted tubule epithelial cell (CL1000849)
Fold Change: 2.8
Marker Score: 2973 - Cell Name: bronchial goblet cell (CL1000312)
Fold Change: 2.79
Marker Score: 1378 - Cell Name: P/D1 enteroendocrine cell (CL0002268)
Fold Change: 2.79
Marker Score: 1039 - Cell Name: myofibroblast cell (CL0000186)
Fold Change: 2.78
Marker Score: 3437 - Cell Name: pericyte (CL0000669)
Fold Change: 2.77
Marker Score: 1620 - Cell Name: blood cell (CL0000081)
Fold Change: 2.76
Marker Score: 32136 - Cell Name: skeletal muscle fibroblast (CL0011027)
Fold Change: 2.73
Marker Score: 1799 - Cell Name: conjunctival epithelial cell (CL1000432)
Fold Change: 2.72
Marker Score: 2868 - Cell Name: elicited macrophage (CL0000861)
Fold Change: 2.72
Marker Score: 16503 - Cell Name: epithelial cell of lower respiratory tract (CL0002632)
Fold Change: 2.7
Marker Score: 11277 - Cell Name: kidney connecting tubule epithelial cell (CL1000768)
Fold Change: 2.7
Marker Score: 3824 - Cell Name: enterocyte of colon (CL1000347)
Fold Change: 2.7
Marker Score: 4160 - Cell Name: lung ciliated cell (CL1000271)
Fold Change: 2.65
Marker Score: 1257 - Cell Name: PP cell (CL0000696)
Fold Change: 2.65
Marker Score: 596 - Cell Name: tracheobronchial serous cell (CL0019001)
Fold Change: 2.63
Marker Score: 962 - Cell Name: professional antigen presenting cell (CL0000145)
Fold Change: 2.6
Marker Score: 1341 - Cell Name: thyroid follicular cell (CL0002258)
Fold Change: 2.59
Marker Score: 2030 - Cell Name: vein endothelial cell (CL0002543)
Fold Change: 2.59
Marker Score: 2342 - Cell Name: dendritic cell (CL0000451)
Fold Change: 2.59
Marker Score: 1776 - Cell Name: fibroblast of connective tissue of prostate (CL1000299)
Fold Change: 2.59
Marker Score: 644 - Cell Name: pulmonary artery endothelial cell (CL1001568)
Fold Change: 2.58
Marker Score: 2222 - Cell Name: granulocyte (CL0000094)
Fold Change: 2.58
Marker Score: 1155
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Other Information
Genular Protein ID: 2360737090
Symbol: CYTC_HUMAN
Name: Cystatin-C
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 3495457
Title: Molecular cloning and sequence analysis of cDNA coding for the precursor of the human cysteine proteinase inhibitor cystatin C.
PubMed ID: 3495457
PubMed ID: 2764935
Title: The human cystatin C gene (CST3) is a member of the cystatin gene family which is localized on chromosome 20.
PubMed ID: 2764935
PubMed ID: 2541223
Title: Stroke in Icelandic patients with hereditary amyloid angiopathy is related to a mutation in the cystatin C gene, an inhibitor of cysteine proteases.
PubMed ID: 2541223
PubMed ID: 2363674
Title: Structure and expression of the human cystatin C gene.
PubMed ID: 2363674
DOI: 10.1042/bj2680287
PubMed ID: 14702039
Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.
PubMed ID: 14702039
DOI: 10.1038/ng1285
PubMed ID: 11780052
Title: The DNA sequence and comparative analysis of human chromosome 20.
PubMed ID: 11780052
DOI: 10.1038/414865a
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 6283552
Title: Human gamma-trace, a basic microprotein: amino acid sequence and presence in the adenohypophysis.
PubMed ID: 6283552
PubMed ID: 6365094
Title: Human cystatin, a new protein inhibitor of cysteine proteinases.
PubMed ID: 6365094
PubMed ID: 6662498
Title: Protein inhibitors of cysteine proteinases. III. Amino-acid sequence of cystatin from chicken egg white.
PubMed ID: 6662498
PubMed ID: 15340161
Title: Signal peptide prediction based on analysis of experimentally verified cleavage sites.
PubMed ID: 15340161
DOI: 10.1110/ps.04682504
PubMed ID: 15274116
Title: Cystatin C as a potential cerebrospinal fluid marker for the diagnosis of Creutzfeldt-Jakob disease.
PubMed ID: 15274116
PubMed ID: 16635487
Title: A dual Golgi- and mitochondria-localised Ala25Ser precursor cystatin C: an additional tool for characterising intracellular mis-localisation leading to increased AMD susceptibility.
PubMed ID: 16635487
PubMed ID: 19838169
Title: Enrichment of glycopeptides for glycan structure and attachment site identification.
PubMed ID: 19838169
DOI: 10.1038/nmeth.1392
PubMed ID: 20189825
Title: Confident assignment of intact mass tags to human salivary cystatins using top-down Fourier-transform ion cyclotron resonance mass spectrometry.
PubMed ID: 20189825
PubMed ID: 21269460
Title: Initial characterization of the human central proteome.
PubMed ID: 21269460
PubMed ID: 22905912
Title: Resveratrol-induced changes of the human adipocyte secretion profile.
PubMed ID: 22905912
DOI: 10.1021/pr300539b
PubMed ID: 26091039
Title: A single kinase generates the majority of the secreted phosphoproteome.
PubMed ID: 26091039
PubMed ID: 25944712
Title: N-terminome analysis of the human mitochondrial proteome.
PubMed ID: 25944712
PubMed ID: 11276250
Title: Human cystatin C, an amyloidogenic protein, dimerizes through three-dimensional domain swapping.
PubMed ID: 11276250
DOI: 10.1038/86188
PubMed ID: 16170782
Title: 3D domain-swapped human cystatin C with amyloid-like intermolecular beta-sheets.
PubMed ID: 16170782
DOI: 10.1002/prot.20633
PubMed ID: 1352269
Title: Hereditary cystatin C amyloid angiopathy: identification of the disease-causing mutation and specific diagnosis by polymerase chain reaction based analysis.
PubMed ID: 1352269
DOI: 10.1007/bf00194306
PubMed ID: 11815350
Title: CST3 genotype associated with exudative age related macular degeneration.
PubMed ID: 11815350
DOI: 10.1136/bjo.86.2.214
Sequence Information:
- Length: 146
- Mass: 15799
- Checksum: 75EF049CAE2E8B2B
- Sequence:
MAGPLRAPLL LLAILAVALA VSPAAGSSPG KPPRLVGGPM DASVEEEGVR RALDFAVGEY NKASNDMYHS RALQVVRARK QIVAGVNYFL DVELGRTTCT KTQPNLDNCP FHDQPHLKRK AFCSFQIYAV PWQGTMTLSK STCQDA
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. For the full schema, download it here.