Genular: Defining Cellular Identity and Function

Details for: Got1

Gene ID: 14718

Symbol: Got1

Ensembl ID: ENSMUSG00000025190

Description: glutamic-oxaloacetic transaminase 1, soluble

Associated with

Aspartate and asparagine metabolism
(R-MMU-8963693)
Glucose metabolism
(R-MMU-70326)
Metabolism
(R-MMU-1430728)
Metabolism of amino acids and derivatives
(R-MMU-71291)
Metabolism of carbohydrates
(R-MMU-71387)
Amino acid biosynthetic process
(GO:0008652)
Amino acid metabolic process
(GO:0006520)
Aspartate biosynthetic process
(GO:0006532)
Aspartate catabolic process
(GO:0006533)
Aspartate metabolic process
(GO:0006531)
Axon terminus
(GO:0043679)
Biosynthetic process
(GO:0009058)
Carboxylic acid binding
(GO:0031406)
Catalytic activity
(GO:0003824)
Cellular response to mechanical stimulus
(GO:0071260)
Cytoplasm
(GO:0005737)
Cytosol
(GO:0005829)
Dicarboxylic acid metabolic process
(GO:0043648)
Fatty acid homeostasis
(GO:0055089)
Gluconeogenesis
(GO:0006094)
Glutamate catabolic process to 2-oxoglutarate
(GO:0019551)
Glutamate catabolic process to aspartate
(GO:0019550)
Glycerol biosynthetic process
(GO:0006114)
L-aspartate:2-oxoglutarate aminotransferase activity
(GO:0004069)
L-cysteine transaminase activity
(GO:0047801)
Negative regulation of collagen biosynthetic process
(GO:0032966)
Negative regulation of cytosolic calcium ion concentration
(GO:0051481)
Negative regulation of mitochondrial depolarization
(GO:0051902)
Notch signaling pathway
(GO:0007219)
Oxaloacetate metabolic process
(GO:0006107)
Phosphatidylserine decarboxylase activity
(GO:0004609)
Positive regulation of transforming growth factor beta receptor signaling pathway
(GO:0030511)
Pyridoxal phosphate binding
(GO:0030170)
Response to transition metal nanoparticle
(GO:1990267)
Transaminase activity
(GO:0008483)
Transdifferentiation
(GO:0060290)
Transferase activity
(GO:0016740)

Other Information

Proteins

Cysteine aminotransferase, cytoplasmic

Genular Protein ID: 813852397

Symbol: AATC_MOUSE

Name: Cysteine aminotransferase, cytoplasmic

UniProtKB Accession Codes:

P05201 Q3UJH8

Database IDs:

Citations:

PubMed ID: 3782150

Title: Cloning and sequence analysis of mRNA for mouse aspartate aminotransferase isoenzymes.

PubMed ID: 3782150

DOI: 10.1016/s0021-9258(19)75987-0

PubMed ID: 3379636

Title: Structural organization of the mouse aspartate aminotransferase isoenzyme genes. Introns antedate the divergence of cytosolic and mitochondrial isoenzyme genes.

PubMed ID: 3379636

DOI: 10.1016/0022-2836(88)90329-4

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 18034455

Title: Large-scale identification and evolution indexing of tyrosine phosphorylation sites from murine brain.

PubMed ID: 18034455

DOI: 10.1021/pr0701254

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

PubMed ID: 21937432

Title: Hydrogen sulfide protects the retina from light-induced degeneration by the modulation of Ca2+ influx.

PubMed ID: 21937432

DOI: 10.1074/jbc.m111.298208

PubMed ID: 23806337

Title: SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways.

PubMed ID: 23806337

DOI: 10.1016/j.molcel.2013.06.001

Sequence Information:

Length: 413
Mass: 46248
Checksum: 0E37C763155EA6B5
Sequence:

MAPPSVFAQV PQAPPVLVFK LTADFRDDPD PRKVNLGVGA YRTDESQPWV LPVVRKVEQK 
IANDNSLNHE YLPILGLAEF RSCASRLVLG DNSLAIRENR VGGVQSLGGT GALRIGADFL 
GRWYNGTDNK NTPIYVSSPT WENHNAVFSA AGFKDIRPYC YWDAEKRGLD LQGFLNDLEN 
APEFSIFVLH ACAHNPTGTD PTPEQWKQIA AVMQRRFLFP FFDSAYQGFA SGDLEKDAWA 
IRYFVSEGFE LFCAQSFSKN FGLYNERVGN LTVVGKESDS VLRVLSQMEK IVRITWSNPP 
AQGARIVAAT LSDPELFKEW KGNVKTMADR ILTMRSELRA RLEALKTPGT WSHITEQIGM 
FSFTGLNPKQ VEYLVNEKHI YLLPSGRINM CGLTTKNLDY VATSIHEAVT KIQ

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Got1

Associated with

Other Information

Cloning and sequence analysis of mRNA for mouse aspartate aminotransferase isoenzymes. PubMed ID: 3782150

Structural organization of the mouse aspartate aminotransferase isoenzyme genes. Introns antedate the divergence of cytosolic and mitochondrial isoenzyme genes. PubMed ID: 3379636

The transcriptional landscape of the mammalian genome. PubMed ID: 16141072

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Large-scale identification and evolution indexing of tyrosine phosphorylation sites from murine brain. PubMed ID: 18034455

A tissue-specific atlas of mouse protein phosphorylation and expression. PubMed ID: 21183079

Hydrogen sulfide protects the retina from light-induced degeneration by the modulation of Ca2+ influx. PubMed ID: 21937432

SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways. PubMed ID: 23806337