CST4 | ENSG00000101441 | NCBI 1472

Details for: CST4

Gene ID: 1472

Symbol: CST4

Ensembl ID: ENSG00000101441

Description: cystatin S

Associated with

Cysteine-type endopeptidase inhibitor activity
(GO:0004869)
Cytoplasm
(GO:0005737)
Detection of chemical stimulus involved in sensory perception of bitter taste
(GO:0001580)
Extracellular exosome
(GO:0070062)
Extracellular space
(GO:0005615)
Negative regulation of cysteine-type endopeptidase activity
(GO:2000117)
Negative regulation of proteolysis
(GO:0045861)
Protein binding
(GO:0005515)
Vesicle
(GO:0031982)

Other Information

Proteins

Cystatin-S

Genular Protein ID: 1736355651

Symbol: CYTS_HUMAN

Name: Cystatin-S

UniProtKB Accession Codes:

P01036 Q9UBI5 Q9UCS9

Database IDs:

Citations:

PubMed ID: 1898352

Title: Human salivary cystatin S. Cloning, sequence analysis, hybridization in situ and immunocytochemistry.

PubMed ID: 1898352

DOI: 10.1042/bj2780627

PubMed ID: 1334620

Title: Characterization of two members (CST4 and CST5) of the cystatin gene family and molecular evolution of cystatin genes.

PubMed ID: 1334620

DOI: 10.1007/978-3-0348-7321-5_43

PubMed ID: 11780052

Title: The DNA sequence and comparative analysis of human chromosome 20.

PubMed ID: 11780052

DOI: 10.1038/414865a

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 3496880

Title: Identification of a long form of cystatin from human saliva by rapid microbore HPLC mapping.

PubMed ID: 3496880

DOI: 10.1016/0006-291x(87)91571-3

PubMed ID: 1747107

Title: Large-scale purification and characterization of the major phosphoproteins and mucins of human submandibular-sublingual saliva.

PubMed ID: 1747107

DOI: 10.1042/bj2800341

PubMed ID: 1778989

Title: Identification of full-sized forms of salivary (S-type) cystatins (cystatin SN, cystatin SA, cystatin S, and two phosphorylated forms of cystatin S) in human whole saliva and determination of phosphorylation sites of cystatin S.

PubMed ID: 1778989

DOI: 10.1093/oxfordjournals.jbchem.a123634

PubMed ID: 1741693

Title: The effects of human salivary cystatins and statherin on hydroxyapatite crystallization.

PubMed ID: 1741693

DOI: 10.1016/0003-9969(91)90014-l

PubMed ID: 6501254

Title: Isolation and amino acid sequence of SAP-1, an acidic protein of human whole saliva, and sequence homology with human gamma-trace.

PubMed ID: 6501254

DOI: 10.1093/oxfordjournals.jbchem.a134861

PubMed ID: 25946035

Title: Human basal tear peptidome characterization by CID, HCD, and ETD followed by in silico and in vitro analyses for antimicrobial peptide identification.

PubMed ID: 25946035

DOI: 10.1021/acs.jproteome.5b00179

PubMed ID: 6394600

Title: Cystatin S: a cysteine proteinase inhibitor of human saliva.

PubMed ID: 6394600

DOI: 10.1093/oxfordjournals.jbchem.a134952

PubMed ID: 1898055

Title: Salivary cystatin SA-III, a potential precursor of the acquired enamel pellicle, is phosphorylated at both its amino- and carboxyl-terminal regions.

PubMed ID: 1898055

DOI: 10.1016/0003-9861(91)90249-i

PubMed ID: 20189825

Title: Confident assignment of intact mass tags to human salivary cystatins using top-down Fourier-transform ion cyclotron resonance mass spectrometry.

PubMed ID: 20189825

DOI: 10.1016/j.jasms.2010.01.025

PubMed ID: 16959974

Title: The consensus coding sequences of human breast and colorectal cancers.

PubMed ID: 16959974

DOI: 10.1126/science.1133427

Sequence Information:

Length: 141
Mass: 16214
Checksum: 65B1FEB8F074DEA6
Sequence:

MARPLCTLLL LMATLAGALA SSSKEENRII PGGIYDADLN DEWVQRALHF AISEYNKATE 
DEYYRRPLQV LRAREQTFGG VNYFFDVEVG RTICTKSQPN LDTCAFHEQP ELQKKQLCSF 
EIYEVPWEDR MSLVNSRCQE A

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: CST4

Associated with

Other Information

Human salivary cystatin S. Cloning, sequence analysis, hybridization in situ and immunocytochemistry. PubMed ID: 1898352

Characterization of two members (CST4 and CST5) of the cystatin gene family and molecular evolution of cystatin genes. PubMed ID: 1334620

The DNA sequence and comparative analysis of human chromosome 20. PubMed ID: 11780052

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Identification of a long form of cystatin from human saliva by rapid microbore HPLC mapping. PubMed ID: 3496880

Large-scale purification and characterization of the major phosphoproteins and mucins of human submandibular-sublingual saliva. PubMed ID: 1747107

Identification of full-sized forms of salivary (S-type) cystatins (cystatin SN, cystatin SA, cystatin S, and two phosphorylated forms of cystatin S) in human whole saliva and determination of phosphorylation sites of cystatin S. PubMed ID: 1778989

The effects of human salivary cystatins and statherin on hydroxyapatite crystallization. PubMed ID: 1741693

Isolation and amino acid sequence of SAP-1, an acidic protein of human whole saliva, and sequence homology with human gamma-trace. PubMed ID: 6501254

Human basal tear peptidome characterization by CID, HCD, and ETD followed by in silico and in vitro analyses for antimicrobial peptide identification. PubMed ID: 25946035

Cystatin S: a cysteine proteinase inhibitor of human saliva. PubMed ID: 6394600

Salivary cystatin SA-III, a potential precursor of the acquired enamel pellicle, is phosphorylated at both its amino- and carboxyl-terminal regions. PubMed ID: 1898055

Confident assignment of intact mass tags to human salivary cystatins using top-down Fourier-transform ion cyclotron resonance mass spectrometry. PubMed ID: 20189825

The consensus coding sequences of human breast and colorectal cancers. PubMed ID: 16959974