Genular: Defining Cellular Identity and Function

Details for: Gp1ba

Gene ID: 14723

Symbol: Gp1ba

Ensembl ID: ENSMUSG00000050675

Description: glycoprotein 1b, alpha polypeptide

Associated with

Formation of fibrin clot (clotting cascade)
(R-MMU-140877)
Gp1b-ix-v activation signalling
(R-MMU-430116)
Intrinsic pathway of fibrin clot formation
(R-MMU-140837)
Platelet activation, signaling and aggregation
(R-MMU-76002)
Platelet adhesion to exposed collagen
(R-MMU-75892)
Platelet aggregation (plug formation)
(R-MMU-76009)
Blood coagulation
(GO:0007596)
Blood coagulation, intrinsic pathway
(GO:0007597)
Cell adhesion
(GO:0007155)
Cell morphogenesis
(GO:0000902)
Cell surface
(GO:0009986)
External side of plasma membrane
(GO:0009897)
Extracellular matrix
(GO:0031012)
Extracellular space
(GO:0005615)
Fibrinolysis
(GO:0042730)
Glycoprotein ib-ix-v complex
(GO:1990779)
Hemostasis
(GO:0007599)
Megakaryocyte development
(GO:0035855)
Membrane
(GO:0016020)
Plasma membrane
(GO:0005886)
Positive regulation of leukocyte tethering or rolling
(GO:1903238)
Positive regulation of platelet activation
(GO:0010572)
Release of sequestered calcium ion into cytosol
(GO:0051209)

Other Information

Proteins

Platelet glycoprotein Ib alpha chain

Genular Protein ID: 1275186730

Symbol: GP1BA_MOUSE

Name: Platelet glycoprotein Ib alpha chain

UniProtKB Accession Codes:

O35930 Q5SX47

Database IDs:

Citations:

PubMed ID: 9410473

Title: Cloning of the murine platelet glycoprotein Ib(alpha) gene highlighting species-specific platelet adhesion.

PubMed ID: 9410473

DOI: 10.1006/bcmd.1997.0146

PubMed ID: 19468303

Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.

PubMed ID: 19468303

DOI: 10.1371/journal.pbio.1000112

PubMed ID: 12907434

Title: Metalloproteinase inhibitors improve the recovery and hemostatic function of in vitro-aged or -injured mouse platelets.

PubMed ID: 12907434

DOI: 10.1182/blood-2003-04-1305

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

PubMed ID: 11858495

Title: Molecular modeling of the seven tandem leucine-rich repeats within the ligand-binding region of platelet glycoprotein Ib alpha.

PubMed ID: 11858495

Sequence Information:

Length: 734
Mass: 80055
Checksum: FA42553EC2ED4D0A
Sequence:

MALLILLFLL PSPLHSQHTC SISKVTSLLE VNCENKKLTA LPADLPADTG ILHLGENQLG 
TFSTASLVHF THLTYLYLDR CELTSLQTNG KLIKLENLDL SHNNLKSLPS LGWALPALTT 
LDVSFNKLGS LSPGVLDGLS QLQELYLQNN DLKSLPPGLL LPTTKLKKLN LANNKLRELP 
SGLLDGLEDL DTLYLQRNWL RTIPKGFFGT LLLPFVFLHA NSWYCDCEIL YFRHWLQENA 
NNVYLWKQGV DVKDTTPNVA SVRCANLDNA PVYSYPGKGC PTSSGDTDYD DYDDIPDVPA 
TRTEVKFSTN TKVHTTHWSL LAAAPSTSQD SQMISLPPTH KPTKKQSTFI HTQSPGFTTL 
PETMESNPTF YSLKLNTVLI PSPTTLEPTS TQATPEPNIQ PMLTTSTLTT PEHSTTPVPT 
TTILTTPEHS TIPVPTTAIL TTPKPSTIPV PTTATLTTLE PSTTPVPTTA TLTTPEPSTT 
LVPTTATLTT PEHSTTPVPT TATLTTPEHS TTPVPTTATL TTPEPSTTLT NLVSTISPVL 
TTTLTTPEST PIETILEQFF TTELTLLPTL ESTTTIIPEQ NSFLNLPEVA LVSSDTSESS 
PFLNSDFCCF LPLGFYVLGL LWLLFASVVL ILLLTWTWHV TPHSLDMEQS AALATSTHTT 
SLEVQRARQV TMPRAWLLFL QGSLPTFRSS LFLWVRPNGR VGPLVAGRRP SALSQGRGQD 
LLGTVGIRYS GHSL

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Gp1ba

Associated with

Other Information

Cloning of the murine platelet glycoprotein Ib(alpha) gene highlighting species-specific platelet adhesion. PubMed ID: 9410473

Lineage-specific biology revealed by a finished genome assembly of the mouse. PubMed ID: 19468303

Metalloproteinase inhibitors improve the recovery and hemostatic function of in vitro-aged or -injured mouse platelets. PubMed ID: 12907434