Genular: Defining Cellular Identity and Function

Details for: Gpc4

Gene ID: 14735

Symbol: Gpc4

Ensembl ID: ENSMUSG00000031119

Description: glypican 4

Associated with

A tetrasaccharide linker sequence is required for gag synthesis
(R-MMU-1971475)
Chondroitin sulfate/dermatan sulfate metabolism
(R-MMU-1793185)
Glycosaminoglycan metabolism
(R-MMU-1630316)
Heparan sulfate/heparin (hs-gag) metabolism
(R-MMU-1638091)
Hs-gag biosynthesis
(R-MMU-2022928)
Hs-gag degradation
(R-MMU-2024096)
Metabolism
(R-MMU-1430728)
Metabolism of carbohydrates
(R-MMU-71387)
Metabolism of fat-soluble vitamins
(R-MMU-6806667)
Metabolism of vitamins and cofactors
(R-MMU-196854)
Retinoid metabolism and transport
(R-MMU-975634)
Sensory perception
(R-MMU-9709957)
Visual phototransduction
(R-MMU-2187338)
Cell migration
(GO:0016477)
Cell surface
(GO:0009986)
Collagen-containing extracellular matrix
(GO:0062023)
External side of plasma membrane
(GO:0009897)
Extracellular region
(GO:0005576)
Extracellular space
(GO:0005615)
Glutamatergic synapse
(GO:0098978)
Golgi lumen
(GO:0005796)
Membrane
(GO:0016020)
Plasma membrane
(GO:0005886)
Presynaptic membrane
(GO:0042734)
Regulation of neurotransmitter receptor localization to postsynaptic specialization membrane
(GO:0098696)
Regulation of presynapse assembly
(GO:1905606)
Regulation of signal transduction
(GO:0009966)
Side of membrane
(GO:0098552)
Synapse
(GO:0045202)
Synaptic membrane adhesion
(GO:0099560)
Wnt signaling pathway
(GO:0016055)

Other Information

Proteins

Glypican-4

Genular Protein ID: 2467147523

Symbol: GPC4_MOUSE

Name: Glypican-4

UniProtKB Accession Codes:

P51655 Q923C8

Database IDs:

Citations:

PubMed ID: 7657705

Title: K-glypican: a novel GPI-anchored heparan sulfate proteoglycan that is highly expressed in developing brain and kidney.

PubMed ID: 7657705

DOI: 10.1083/jcb.130.5.1207

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

PubMed ID: 30982611

Title: Pathogenic variants in GPC4 cause Keipert Syndrome.

PubMed ID: 30982611

DOI: 10.1016/j.ajhg.2019.02.026

Sequence Information:

Length: 557
Mass: 62586
Checksum: F216AA0FEF5ED840
Sequence:

MARLGLLALL CTLAALSASL LAAELKSKSC SEVRRLYVSK GFNKNDAPLY EINGDHLKIC 
PQDYTCCSQE MEEKYSLQSK DDFKTVVSEQ CNHLQAIFAS RYKKFDEFFK ELLENAEKSL 
NDMFVKTYGH LYMQNSELFK DLFVELKRYY VAGNVNLEEM LNDFWARLLE RMFRLVNSQY 
HFTDEYLECV SKYTEQLKPF GDVPRKLKLQ VTRAFVAART FAQGLAVARD VVSKVSVVNP 
TAQCTHALLK MIYCSHCRGL VTVKPCYNYC SNIMRGCLAN QGDLDFEWNN FIDAMLMVAE 
RLEGPFNIES VMDPIDVKIS DAIMNMQDNS VQVSQKVFQG CGPPKPLPAG RISRSISESA 
FSARFRPYHP EQRPTTAAGT SLDRLVTDVK EKLKQAKKFW SSLPSTVCND ERMAAGNENE 
DDCWNGKGKS RYLFAVTGNG LANQGNNPEV QVDTSKPDIL ILRQIMALRV MTSKMKNAYN 
GNDVDFFDIS DESSGEGSGS GCEYQQCPSE FEYNATDHSG KSANEKADSA GGAHAEAKPY 
LLAALCILFL AVQGEWR

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Gpc4

Associated with

Other Information

K-glypican: a novel GPI-anchored heparan sulfate proteoglycan that is highly expressed in developing brain and kidney. PubMed ID: 7657705

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

A tissue-specific atlas of mouse protein phosphorylation and expression. PubMed ID: 21183079

Pathogenic variants in GPC4 cause Keipert Syndrome. PubMed ID: 30982611

Database document:

PubMed ID: 7657705

PubMed ID: 15489334

PubMed ID: 21183079

PubMed ID: 30982611