Details for: CST6

Gene ID: 1474

Symbol: CST6

Ensembl ID: ENSG00000175315

Description: cystatin E/M

Associated with

Other Information

Genular Protein ID: 1532071121

Symbol: CYTM_HUMAN

Name: Cystatin-M

UniProtKB Accession Codes:

Q15828 Q540N7

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 1 CDD 1 CTD 1 DMDM 1 DNASU 1 DisGeNET 1 EMBL 4 Ensembl 1 GO 5 Gene3D 1 GeneCards 1 GeneTree 1 GeneWiki 1 Genevisible 1 GenomeRNAi 1 GlyCosmos 1 GlyGen 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 3 KEGG 1 MANE-Select 1 MEROPS 1 MIM 3 MINT 1 MalaCards 1 MassIVE 1 MaxQB 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PDB 7 PDBsum 5 PRO 1 PROSITE 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 1 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 1 RNAct 1 RefSeq 1 SMART 1 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 UCSC 1 UniProtKB 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 8995380

Title: Identification, cloning, and characterization of cystatin M, a novel cysteine proteinase inhibitor, down-regulated in breast cancer.

PubMed ID: 8995380

DOI: 10.1074/jbc.272.2.903

PubMed ID: 9099741

Title: Cystatin E is a novel human cysteine proteinase inhibitor with structural resemblance to family 2 cystatins.

PubMed ID: 9099741

DOI: 10.1074/jbc.272.16.10853

PubMed ID: 12839564

Title: The human cystatin M/E gene (CST6): exclusion candidate gene for harlequin ichthyosis.

PubMed ID: 12839564

DOI: 10.1046/j.1523-1747.2003.12312.x

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 11348457

Title: Cystatin M/E expression is restricted to differentiated epidermal keratinocytes and sweat glands: a new skin-specific proteinase inhibitor that is a target for cross-linking by transglutaminase.

PubMed ID: 11348457

DOI: 10.1046/j.1523-1747.2001.01309.x

PubMed ID: 30425301

Title: Deficiency of the human cysteine protease inhibitor cystatin M/E causes hypotrichosis and dry skin.

PubMed ID: 30425301

DOI: 10.1038/s41436-018-0355-3

Sequence Information:

  • Length: 149
  • Mass: 16511
  • Checksum: 2076A78BFC9FAC8C
  • Sequence:
    • MARSNLPLAL GLALVAFCLL ALPRDARARP QERMVGELRD LSPDDPQVQK AAQAAVASYN 
MGSNSIYYFR DTHIIKAQSQ LVAGIKYFLT MEMGSTDCRK TRVTGDHVDL TTCPLAAGAQ 
QEKLRCDFEV LVVPWQNSSQ LLKHNCVQM

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.