Genular: Defining Cellular Identity and Function

Details for: Cmklr1

Gene ID: 14747

Symbol: Cmklr1

Ensembl ID: ENSMUSG00000042190

Description: chemerin chemokine-like receptor 1

Associated with

Class a/1 (rhodopsin-like receptors)
(R-MMU-373076)
Gpcr ligand binding
(R-MMU-500792)
Signaling by gpcr
(R-MMU-372790)
Adipokinetic hormone binding
(GO:0097004)
Adipokinetic hormone receptor activity
(GO:0097003)
Chemotaxis
(GO:0006935)
Complement receptor activity
(GO:0004875)
Complement receptor mediated signaling pathway
(GO:0002430)
G protein-coupled receptor activity
(GO:0004930)
G protein-coupled receptor signaling pathway
(GO:0007186)
Inflammatory response
(GO:0006954)
Membrane
(GO:0016020)
Negative regulation of interleukin-12 production
(GO:0032695)
Negative regulation of nf-kappab transcription factor activity
(GO:0032088)
Phospholipase c-activating g protein-coupled receptor signaling pathway
(GO:0007200)
Plasma membrane
(GO:0005886)
Positive regulation of cold-induced thermogenesis
(GO:0120162)
Positive regulation of cytosolic calcium ion concentration
(GO:0007204)
Positive regulation of fat cell differentiation
(GO:0045600)
Positive regulation of macrophage chemotaxis
(GO:0010759)
Regulation of calcium-mediated signaling
(GO:0050848)
Signal transduction
(GO:0007165)

Other Information

Proteins

Chemerin-like receptor 1

Genular Protein ID: 3821156775

Symbol: CML1_MOUSE

Name: Chemerin-like receptor 1

UniProtKB Accession Codes:

P97468

Database IDs:

Citations:

PubMed ID: 9144535

Title: A novel G protein-coupled receptor with homology to neuropeptide and chemoattractant receptors expressed during bone development.

PubMed ID: 9144535

DOI: 10.1006/bbrc.1997.6455

PubMed ID: 15753205

Title: Stereochemical assignment, antiinflammatory properties, and receptor for the omega-3 lipid mediator resolvin E1.

PubMed ID: 15753205

DOI: 10.1084/jem.20042031

PubMed ID: 16863918

Title: Chemokine-like receptor 1 expression by macrophages in vivo: regulation by TGF-beta and TLR ligands.

PubMed ID: 16863918

DOI: 10.1016/j.exphem.2006.03.011

PubMed ID: 17767914

Title: Chemerin--a new adipokine that modulates adipogenesis via its own receptor.

PubMed ID: 17767914

DOI: 10.1016/j.bbrc.2007.08.104

PubMed ID: 17635925

Title: Chemerin, a novel adipokine that regulates adipogenesis and adipocyte metabolism.

PubMed ID: 17635925

DOI: 10.1074/jbc.m700793200

PubMed ID: 18242188

Title: Chemerin enhances insulin signaling and potentiates insulin-stimulated glucose uptake in 3T3-L1 adipocytes.

PubMed ID: 18242188

DOI: 10.1016/j.febslet.2008.01.023

PubMed ID: 19841182

Title: Mouse ChemR23 is expressed in dendritic cell subsets and macrophages, and mediates an anti-inflammatory activity of chemerin in a lung disease model.

PubMed ID: 19841182

DOI: 10.4049/jimmunol.0901037

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

Sequence Information:

Length: 371
Mass: 41815
Checksum: CDBE19305244C0B3
Sequence:

MEYDAYNDSG IYDDEYSDGF GYFVDLEEAS PWEAKVAPVF LVVIYSLVCF LGLLGNGLVI 
VIATFKMKKT VNTVWFVNLA VADFLFNIFL PMHITYAAMD YHWVFGKAMC KISNFLLSHN 
MYTSVFLLTV ISFDRCISVL LPVWSQNHRS IRLAYMTCSA VWVLAFFLSS PSLVFRDTAN 
IHGKITCFNN FSLAAPESSP HPAHSQVVST GYSRHVAVTV TRFLCGFLIP VFIITACYLT 
IVFKLQRNRL AKNKKPFKII ITIIITFFLC WCPYHTLYLL ELHHTAVPSS VFSLGLPLAT 
AVAIANSCMN PILYVFMGHD FRKFKVALFS RLANALSEDT GPSSYPSHRS FTKMSSLNEK 
ASVNEKETST L

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Cmklr1

Associated with

Other Information

A novel G protein-coupled receptor with homology to neuropeptide and chemoattractant receptors expressed during bone development. PubMed ID: 9144535

Stereochemical assignment, antiinflammatory properties, and receptor for the omega-3 lipid mediator resolvin E1. PubMed ID: 15753205

Chemokine-like receptor 1 expression by macrophages in vivo: regulation by TGF-beta and TLR ligands. PubMed ID: 16863918

Chemerin--a new adipokine that modulates adipogenesis via its own receptor. PubMed ID: 17767914

Chemerin, a novel adipokine that regulates adipogenesis and adipocyte metabolism. PubMed ID: 17635925

Chemerin enhances insulin signaling and potentiates insulin-stimulated glucose uptake in 3T3-L1 adipocytes. PubMed ID: 18242188

Mouse ChemR23 is expressed in dendritic cell subsets and macrophages, and mediates an anti-inflammatory activity of chemerin in a lung disease model. PubMed ID: 19841182

A tissue-specific atlas of mouse protein phosphorylation and expression. PubMed ID: 21183079