Genular: Defining Cellular Identity and Function

Details for: Gpi1

Gene ID: 14751

Symbol: Gpi1

Ensembl ID: ENSMUSG00000036427

Description: glucose-6-phosphate isomerase 1

Associated with

Gene expression (transcription)
(R-MMU-74160)
Generic transcription pathway
(R-MMU-212436)
Glucose metabolism
(R-MMU-70326)
Glycolysis
(R-MMU-70171)
Immune system
(R-MMU-168256)
Innate immune system
(R-MMU-168249)
Metabolism
(R-MMU-1430728)
Metabolism of carbohydrates
(R-MMU-71387)
Neutrophil degranulation
(R-MMU-6798695)
Rna polymerase ii transcription
(R-MMU-73857)
Tp53 regulates metabolic genes
(R-MMU-5628897)
Transcriptional regulation by tp53
(R-MMU-3700989)
Canonical glycolysis
(GO:0061621)
Carbohydrate derivative binding
(GO:0097367)
Carbohydrate derivative metabolic process
(GO:1901135)
Ciliary membrane
(GO:0060170)
Cytokine activity
(GO:0005125)
Cytoplasm
(GO:0005737)
Cytosol
(GO:0005829)
Erythrocyte homeostasis
(GO:0034101)
Extracellular region
(GO:0005576)
Extracellular space
(GO:0005615)
Gluconeogenesis
(GO:0006094)
Glucose-6-phosphate isomerase activity
(GO:0004347)
Glucose 6-phosphate metabolic process
(GO:0051156)
Glucose homeostasis
(GO:0042593)
Glycolytic process
(GO:0006096)
Glycolytic process through glucose-6-phosphate
(GO:0061620)
Growth factor activity
(GO:0008083)
In utero embryonic development
(GO:0001701)
Isomerase activity
(GO:0016853)
Mesoderm formation
(GO:0001707)
Monosaccharide binding
(GO:0048029)
Myelin sheath
(GO:0043209)
Negative regulation of neuron apoptotic process
(GO:0043524)
Plasma membrane
(GO:0005886)
Positive regulation of endothelial cell migration
(GO:0010595)
Positive regulation of immunoglobulin production
(GO:0002639)
Protein binding
(GO:0005515)
Ubiquitin protein ligase binding
(GO:0031625)

Other Information

Proteins

G6PI_MOUSE

Genular Protein ID: 4127910186

Symbol: G6PI_MOUSE

Name: N/A

UniProtKB Accession Codes:

P06745 O89062 Q3TEE7 Q3TW50 Q3UUX1 Q3UY84 Q3UZJ1 Q5RJI3 Q8C675 Q9JM07

Database IDs:

Citations:

PubMed ID: 3764429

Title: Molecular cloning and expression of neuroleukin, a neurotrophic factor for spinal and sensory neurons.

PubMed ID: 3764429

DOI: 10.1126/science.3764429

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 19468303

Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.

PubMed ID: 19468303

DOI: 10.1371/journal.pbio.1000112

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 9798653

Title: Expressed genes in interleukin-4 treated B cells identified by cDNA representational difference analysis.

PubMed ID: 9798653

DOI: 10.1016/s0161-5890(98)00031-5

PubMed ID: 7545951

Title: Identification of a novel tandemly repeated sequence present in an intron of the glucose phosphate isomerase (GPI) gene in mouse and man.

PubMed ID: 7545951

DOI: 10.1006/geno.1994.1233

PubMed ID: 7277315

Title: An electrophoretically detectable modification of glucosephosphate isomerase in mouse spermatozoa.

PubMed ID: 7277315

DOI: 10.1530/jrf.0.0630169

PubMed ID: 3352745

Title: Mouse glucose-6-phosphate isomerase and neuroleukin have identical 3' sequences.

PubMed ID: 3352745

DOI: 10.1038/332455a0

PubMed ID: 2344351

Title: Glucose phosphate isomerase enzyme-activity mutants in Mus musculus: genetical and biochemical characterization.

PubMed ID: 2344351

DOI: 10.1007/bf00554824

PubMed ID: 8417789

Title: Glucose-6-phosphate isomerase deficiency associated with nonspherocytic hemolytic anemia in the mouse: an animal model for the human disease.

PubMed ID: 8417789

PubMed ID: 8922529

Title: Genetic evidence that glycolysis is necessary for gastrulation in the mouse.

PubMed ID: 8922529

DOI: 10.1002/(sici)1097-0177(199611)207:3<300::aid-aja7>3.0.co;2-l

PubMed ID: 8674049

Title: Tumor cell autocrine motility factor is the neuroleukin/phosphohexose isomerase polypeptide.

PubMed ID: 8674049

PubMed ID: 16139798

Title: Proteomic identification of proteins conjugated to ISG15 in mouse and human cells.

PubMed ID: 16139798

DOI: 10.1016/j.bbrc.2005.08.132

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

PubMed ID: 23806337

Title: SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways.

PubMed ID: 23806337

DOI: 10.1016/j.molcel.2013.06.001

PubMed ID: 15342241

Title: The crystal structure of mouse phosphoglucose isomerase at 1.6A resolution and its complex with glucose 6-phosphate reveals the catalytic mechanism of sugar ring opening.

PubMed ID: 15342241

DOI: 10.1016/j.jmb.2004.07.085

PubMed ID: 16375918

Title: Crystal structures of mouse autocrine motility factor in complex with carbohydrate phosphate inhibitors provide insight into structure-activity relationship of the inhibitors.

PubMed ID: 16375918

DOI: 10.1016/j.jmb.2005.11.076

Sequence Information:

Length: 558
Mass: 62767
Checksum: 7299E98B12B4C375
Sequence:

MAALTRNPQF QKLLEWHRAN SANLKLRELF EADPERFNNF SLNLNTNHGH ILVDYSKNLV 
NKEVMQMLVE LAKSRGVEAA RDNMFSGSKI NYTENRAVLH VALRNRSNTP IKVDGKDVMP 
EVNRVLDKMK SFCQRVRSGD WKGYTGKSIT DIINIGIGGS DLGPLMVTEA LKPYSKGGPR 
VWFVSNIDGT HIAKTLASLS PETSLFIIAS KTFTTQETIT NAETAKEWFL EAAKDPSAVA 
KHFVALSTNT AKVKEFGIDP QNMFEFWDWV GGRYSLWSAI GLSIALHVGF DHFEQLLSGA 
HWMDQHFLKT PLEKNAPVLL ALLGIWYINC YGCETHALLP YDQYMHRFAA YFQQGDMESN 
GKYITKSGAR VDHQTGPIVW GEPGTNGQHA FYQLIHQGTK MIPCDFLIPV QTQHPIRKGL 
HHKILLANFL AQTEALMKGK LPEEARKELQ AAGKSPEDLE KLLPHKVFEG NRPTNSIVFT 
KLTPFILGAL IAMYEHKIFV QGIMWDINSF DQWGVELGKQ LAKKIEPELE GSSAVTSHDS 
STNGLISFIK QQRDTKLE

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Gpi1

Associated with

Other Information

Molecular cloning and expression of neuroleukin, a neurotrophic factor for spinal and sensory neurons. PubMed ID: 3764429

The transcriptional landscape of the mammalian genome. PubMed ID: 16141072

Lineage-specific biology revealed by a finished genome assembly of the mouse. PubMed ID: 19468303

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Expressed genes in interleukin-4 treated B cells identified by cDNA representational difference analysis. PubMed ID: 9798653

Identification of a novel tandemly repeated sequence present in an intron of the glucose phosphate isomerase (GPI) gene in mouse and man. PubMed ID: 7545951

An electrophoretically detectable modification of glucosephosphate isomerase in mouse spermatozoa. PubMed ID: 7277315

Mouse glucose-6-phosphate isomerase and neuroleukin have identical 3' sequences. PubMed ID: 3352745

Glucose phosphate isomerase enzyme-activity mutants in Mus musculus: genetical and biochemical characterization. PubMed ID: 2344351

Glucose-6-phosphate isomerase deficiency associated with nonspherocytic hemolytic anemia in the mouse: an animal model for the human disease. PubMed ID: 8417789

Genetic evidence that glycolysis is necessary for gastrulation in the mouse. PubMed ID: 8922529

Tumor cell autocrine motility factor is the neuroleukin/phosphohexose isomerase polypeptide. PubMed ID: 8674049

Proteomic identification of proteins conjugated to ISG15 in mouse and human cells. PubMed ID: 16139798

A tissue-specific atlas of mouse protein phosphorylation and expression. PubMed ID: 21183079

SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways. PubMed ID: 23806337

The crystal structure of mouse phosphoglucose isomerase at 1.6A resolution and its complex with glucose 6-phosphate reveals the catalytic mechanism of sugar ring opening. PubMed ID: 15342241

Crystal structures of mouse autocrine motility factor in complex with carbohydrate phosphate inhibitors provide insight into structure-activity relationship of the inhibitors. PubMed ID: 16375918