Details for: Gpr50

Gene ID: 14765

Symbol: Gpr50

Ensembl ID: ENSMUSG00000056380

Description: G-protein-coupled receptor 50

Associated with

Other Information

Genular Protein ID: 4132558600

Symbol: MTR1L_MOUSE

Name: Melatonin-related receptor

UniProtKB Accession Codes:

O88495 Q3V1S8

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CCDS 1 CTD 1 DNASU 1 EMBL 5 Ensembl 1 GO 5 Gene3D 1 GeneTree 1 Genevisible 1 GlyGen 1 HOGENOM 1 InParanoid 1 IntAct 1 InterPro 4 KEGG 1 MGI 1 NCBI Taxonomy 1 OMA 1 OrthoDB 1 PANTHER 2 PRINTS 3 PRO 1 PROSITE 2 PROSITE-ProRule 1 PaxDb 1 PeptideAtlas 1 Pfam 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 1 RNAct 1 RefSeq 2 SAM 1 SMART 1 SMR 1 STRING 1 SUPFAM 1 TreeFam 1 UCSC 1 UniProtKB 1 VEuPathDB 1 eggNOG 1 iPTMnet 1

Citations:

PubMed ID: 9933574

Title: Assignment of the melatonin-related receptor to human chromosome X (GPR50) and mouse chromosome X (Gpr50).

PubMed ID: 9933574

DOI: 10.1006/geno.1998.5661

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 19468303

Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.

PubMed ID: 19468303

DOI: 10.1371/journal.pbio.1000112

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 17957037

Title: Altered metabolism in the melatonin-related receptor (GPR50) knockout mouse.

PubMed ID: 17957037

DOI: 10.1152/ajpendo.00199.2007

PubMed ID: 19699797

Title: GPR50 interacts with neuronal NOGO-A and affects neurite outgrowth.

PubMed ID: 19699797

DOI: 10.1016/j.mcn.2009.08.007

PubMed ID: 21858214

Title: GPR50 interacts with TIP60 to modulate glucocorticoid receptor signalling.

PubMed ID: 21858214

DOI: 10.1371/journal.pone.0023725

PubMed ID: 25689717

Title: G protein coupled receptor 50 promotes self-renewal and neuronal differentiation of embryonic neural progenitor cells through regulation of notch and wnt/beta-catenin signalings.

PubMed ID: 25689717

DOI: 10.1016/j.bbrc.2015.02.040

PubMed ID: 29572483

Title: The orphan GPR50 receptor promotes constitutive TGFbeta receptor signaling and protects against cancer development.

PubMed ID: 29572483

DOI: 10.1038/s41467-018-03609-x

Sequence Information:

  • Length: 591
  • Mass: 65130
  • Checksum: 12576D50C20E216A
  • Sequence:
    • MATVPKSNMG PTKAVPTPFG CIGCKLPKPD YPPALIIFMF CAMVITVVVD LIGNSMVILA 
VTKNKKLRNS GNIFVASLSV ADMLVAIYPY PLMLYAMSVG GWDLSQLQCQ MVGLVTGLSV 
VGSIFNITAI AINRYCYICH SLQYKRIFSL RNTCIYLVVT WVMTVLAVLP NMYIGTIEYD 
PRTYTCIFNY VNNPAFTVTI VCIHFVLPLI IVGYCYTKIW IKVLAARDPA GQNPDNQFAE 
VRNFLTMFVI FLLFAVCWCP VNVLTVLVAV IPKEMAGKIP NWLYLAAYCI AYFNSCLNAI 
IYGILNESFR REYWTIFHAM RHPILFISHL ISDIRETWET RALTRARVRA RDQVREQERA 
RACVAVEGTP RNVRNVLLPG DASAPHSDRA SVRPKPQTRS TSVYRKPASI HHKSISGHPK 
SASVYPKPAS SVHCKPASVH FKPASVHFKG DSVYFKGDTV HYRAASKLVT SHRISAGPST 
SHPTSMAGYI KSGTSHPATT TVDYLEPATT SHSVLTAVDL PEVSASHCLE MTSTGHLRAD 
ISASVLPSVP FELAATPPDT TAIPIASGDY RKVVLIDDDS DDSDCSDEMA V

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.