Genular: Defining Cellular Identity and Function

Details for: Grk4

Gene ID: 14772

Symbol: Grk4

Ensembl ID: ENSMUSG00000052783

Description: G protein-coupled receptor kinase 4

Associated with

Inactivation, recovery and regulation of the phototransduction cascade
(R-MMU-2514859)
Sensory perception
(R-MMU-9709957)
The phototransduction cascade
(R-MMU-2514856)
Visual phototransduction
(R-MMU-2187338)
Atp binding
(GO:0005524)
Cytoplasm
(GO:0005737)
Cytosol
(GO:0005829)
Dendrite
(GO:0030425)
Desensitization of g protein-coupled receptor signaling pathway
(GO:0002029)
G protein-coupled receptor internalization
(GO:0002031)
G protein-coupled receptor kinase activity
(GO:0004703)
Kinase activity
(GO:0016301)
Neuronal cell body
(GO:0043025)
Nucleotide binding
(GO:0000166)
Phosphorylation
(GO:0016310)
Plasma membrane
(GO:0005886)
Protein kinase activity
(GO:0004672)
Protein phosphorylation
(GO:0006468)
Protein serine/threonine kinase activity
(GO:0004674)
Receptor internalization
(GO:0031623)
Regulation of signal transduction
(GO:0009966)
Rhodopsin kinase activity
(GO:0050254)
Signal transduction
(GO:0007165)
Transferase activity
(GO:0016740)

Other Information

Proteins

G protein-coupled receptor kinase 4
Q8BP13_MOUSE

Genular Protein ID: 2290768706

Symbol: GRK4_MOUSE

Name: G protein-coupled receptor kinase 4

UniProtKB Accession Codes:

O70291 Q3V151

Database IDs:

Citations:

PubMed ID: 10506199

Title: The GRK4 subfamily of G protein-coupled receptor kinases. Alternative splicing, gene organization, and sequence conservation.

PubMed ID: 10506199

DOI: 10.1074/jbc.274.41.29381

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

Sequence Information:

Length: 574
Mass: 66928
Checksum: 7D7D6F46C9C044B6
Sequence:

MELENFVANN LLLKARLGFN KQTGRSKKWR ELLKFPPVSM CTELRWSIEK DFSSLCDKQP 
IGRLLFRQFC DTKPDLKRCI EFLDAVAEYE VTIEEEQREF GLAIFSRFFK EKSEVPLPEI 
PPDIVKECKW NLKQNSPSQN VFEECAGIVC KYLSETPFEE YQESTYFNRF LQWKWLERRP 
VTKNTFRQYR VLGKGGFGEV CACQVRATGK MYACKKLEKK RIKKRKGEAM ALNEKRILEK 
LHSRFVVSLA YTYETKDALC LVLTIMNGGD LKYHIYNLGD PGFEEPRAVF YAAELCCGLE 
DLQRKRIVYR DLKPENILLD DHGHIRISDL GLAMEVPEGE MVRGRVGTVG YMAPEIINHE 
KYTFSPDWWG LGCLIYEMIA GHSPFRKYKE KVNREELERR VKNETEEYSE RFSEDAKSIC 
SMLLIKDPSK RLGCQRDGVS AVKQHPIFKD INFSRLEANM LDPPFIPDPQ AIYCRNILDI 
GQFSVVKGVN LDTNDEIFYA EFATGSVTIP WQNEMIESGC FKDLNENEDD LSSLEKYKMC 
SSILRPKRNF FRRLFRRTGC LNIALSEERE PTEH

Genular Protein ID: 2568588904

Symbol: Q8BP13_MOUSE

Name: N/A

UniProtKB Accession Codes:

Q8BP13

Database IDs:

Citations:

PubMed ID: 10349636

Title: High-efficiency full-length cDNA cloning.

PubMed ID: 10349636

DOI: 10.1016/S0076-6879(99)03004-9

PubMed ID: 11042159

Title: Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes.

PubMed ID: 11042159

DOI: 10.1101/gr.145100

PubMed ID: 11076861

Title: RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer.

PubMed ID: 11076861

DOI: 10.1101/gr.152600

PubMed ID: 11217851

Title: Functional annotation of a full-length mouse cDNA collection.

PubMed ID: 11217851

DOI: 10.1038/35055500

PubMed ID: 12466851

Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.

PubMed ID: 12466851

DOI: 10.1038/nature01266

PubMed ID: 16141073

Title: Antisense Transcription in the Mammalian Transcriptome.

PubMed ID: 16141073

DOI: 10.1126/science.1112009

PubMed ID: 19468303

Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.

PubMed ID: 19468303

DOI: 10.1371/journal.pbio.1000112

Sequence Information:

Length: 177
Mass: 20686
Checksum: 4EE1D67CCA6CE279
Sequence:

MELENFVANN LLLKARLGFN KQTGRSKKWR ELLKFPPVSM CTELRWSIEK DFSSLCDKQP 
IGRLLFRQFC DTKPDLKRCI EFLDAVAEYE VTIEEEQREF GLAIFSRFFK EKSEVPLPEI 
PPDIVKECKW NLKQNSPSQN VFEECAGFSV SRVVSLWDPK RTQMPAQAYT QKNSQLP

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Grk4

Associated with

Other Information

The GRK4 subfamily of G protein-coupled receptor kinases. Alternative splicing, gene organization, and sequence conservation. PubMed ID: 10506199

The transcriptional landscape of the mammalian genome. PubMed ID: 16141072

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

High-efficiency full-length cDNA cloning. PubMed ID: 10349636

Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes. PubMed ID: 11042159

RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer. PubMed ID: 11076861

Functional annotation of a full-length mouse cDNA collection. PubMed ID: 11217851

Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. PubMed ID: 12466851

Antisense Transcription in the Mammalian Transcriptome. PubMed ID: 16141073

Lineage-specific biology revealed by a finished genome assembly of the mouse. PubMed ID: 19468303